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Understanding How The Environment Shapes Mutualism

Research Project

Project/Area Number 19K06795
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 45020:Evolutionary biology-related
Research InstitutionOkinawa Institute of Science and Technology Graduate University

Principal Investigator

Denton Jai  沖縄科学技術大学院大学, ゲノム・遺伝子制御システム科学ユニット, 客員研究員 (10795389)

Project Period (FY) 2019-04-01 – 2021-03-31
Project Status Discontinued (Fiscal Year 2020)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2021: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2020: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2019: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
KeywordsSymbiosis / Yeast / Drosophila / Gene regulation / Evolution / Outreach / Mutualism / Synthetic Biology / Population Dynamics
Outline of Research at the Start

Which ecosystem changes (environmental factors or the behavior or abundance of resident organisms) disrupt the delicate balance? Are there clear thresholds at which these changes have a strong detrimental effect on an ecosystem?

Outline of Annual Research Achievements

As I have now left Japan I have suspended the grant.
However, prior to this suspension several pieces of work have been completed. This year saw the publication of an mSystems paper exploring yeast symbiosis. Moreover, additional pieces of work are currently in submission with the hope of submitting the final pieces in quarter 2 of 2021.
More specifically, work detailing Drosophila gene regulation is current under review and a paper detailing high school student outreach is also under review. Currently there are 4 additional manuscripts relating to this grant that will be submitted as soon as possible. One will detail 4-strain yeast system and the associated modelling. Unfortunately the publication of the work sooner was complicated by COVID-mediated difficulties in collaboration but it is now on track again. There is also two gene regulation papers and a policy paper that was supported by this grant.
I feel that all research needs to have wide public impact. In addition to the hard laboratory-based science I am thrilled that this work has also included both outreach and policy pieces. This has facilitated the communication of our results and contributed to science discussion beyond the niche of symbiosis researchers.

Report

(2 results)
  • 2020 Annual Research Report
  • 2019 Research-status Report
  • Research Products

    (3 results)

All 2020

All Journal Article (3 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 1 results,  Open Access: 2 results)

  • [Journal Article] Synthetic Symbiosis under Environmental Disturbances2020

    • Author(s)
      Denton Jai A.、Gokhale Chaitanya S.
    • Journal Title

      mSystems

      Volume: 5 Issue: 3

    • DOI

      10.1128/msystems.00187-20

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cross-species Transcriptomic Network Analysis Reveals Links Between Ribosomal Protein Mutation and Cancer2020

    • Author(s)
      Denton Jai A、Velasque Mariana、Reed Floyd A
    • Journal Title

      bioRxiv

      Volume: -

    • DOI

      10.1101/2020.12.11.420604

    • Related Report
      2020 Annual Research Report
    • Open Access / Int'l Joint Research
  • [Journal Article] Synthetic symbiosis under environmental disturbances2020

    • Author(s)
      Jai Denton Chaitanya Gokhale
    • Journal Title

      mSystems

      Volume: In Press

    • Related Report
      2019 Research-status Report

URL: 

Published: 2019-04-18   Modified: 2021-12-27  

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