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Sleep facilitation by Artificial carbonated bathing in healthy elderly

Research Project

Project/Area Number 19K11294
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 59010:Rehabilitation science-related
Research InstitutionAkita University

Principal Investigator

Ito Uemura Sachiko  秋田大学, 医学系研究科, 准教授 (40271829)

Co-Investigator(Kenkyū-buntansha) 神林 崇  筑波大学, 国際統合睡眠医科学研究機構, 教授 (50323150)
長谷川 裕晃  宇都宮大学, 工学部, 教授 (90344770)
Project Period (FY) 2019-04-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2021: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords人工炭酸泉 / 睡眠促進効果 / 高齢者 / 認知機能 / 体温 / 睡眠 / 認知症予防 / 末梢血流量
Outline of Research at the Start

認知症、特にアルツハイマー型認知症(AD)では、睡眠障害がAD発祥の一因になっている可能性がある。規則正しい生活や十分な睡眠時間、睡眠構築(脳波上における徐波睡眠の増加)によってAD発症は軽減される可能性がある。
古来より入浴とりわけ、温泉浴は入眠促進・熟眠効果をもたらすことが知られているが、その理由は、温泉浴による深部体温上昇後に下降する際、入眠効果がみられ、さらなる体温の下降が、熟眠を引き起こすためだと説明されている。
今回我々は、健常高齢者を対象に人工炭酸泉が睡眠促進に効果的であることを、深部体温や脳波、末梢血流量を用いて検証し、その睡眠構築に人工炭酸泉浴が効果的であることを検証する。

Outline of Final Research Achievements

We evaluated the effects of normal (plain hot water; PH) and artificial carbonated bathing (ACB) on sleep using clinical thermometers and EEG in healthy elderly subjects. Nine healthy elderly women (average age 71.3 years old) were divided into 2 groups. Each group took ACB and PH with one week intervals between the two baths. Subjects soaked in the bath (38°C) for 10 min.Subjects were told to sleep from 23:00-6:00. Then, subjects were examined with visual analog scale (VAS) and critical flicker fusion test (CFF).
There was no significant difference in body temperature (proximal, distal, distal-proximal temperature gradient: DPG) before and during sleep between ACB and PH. The condition of the ACB tended to have less light sleep compared to PH (150min vs 201min, p=0.08), but there was no significant difference in the SWS (44.1min vs 39.1min, ns), EEG delta power analysis, VAS and CFF.

Academic Significance and Societal Importance of the Research Achievements

高齢者の不完全な睡眠を、人工炭酸泉浴による体温調節によってメリハリをつけることで、睡眠そのものがもつ回復的な役割を十分に発揮させ、認知症の発症を抑制する戦略は、前例のない独創的な試みである一方で、十分な見込みがあると期待される。また、簡便な人工炭酸泉浴の睡眠への効果を、高齢者に応用できれば、睡眠導入剤を減量しながら医療費の削減にも貢献できると考える。

Report

(6 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (5 results)

All 2022 2020

All Presentation (5 results) (of which Int'l Joint Research: 2 results)

  • [Presentation] 簡易脳波と体温からみた人工炭酸泉浴による高齢者の睡眠促進効果:パイロットスタディ2022

    • Author(s)
      上村佐知子、照井佳乃、佐竹將宏、今西彩、塩谷隆信、神林 崇、西野精治
    • Organizer
      日本睡眠学会第47回定期学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] Sleep facilitation by Artificial carbonated bathing in healthy elderly: EEG, proximal and distal temperature evaluations.2020

    • Author(s)
      Uemura S, Kanbayashi T, Imanishi A, Terui Y, Satake M, Shioya T, Nishino S
    • Organizer
      SLEEP 2020, Virtual Meeting of the Associated Professional Sleep Societies, August 27-30
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] 簡易脳波と体温からみた人工炭酸泉浴による高齢者の睡眠促進効果.2020

    • Author(s)
      上村佐知子,藤浦涼,石谷柊真,竹田有希,照井佳乃,佐竹將宏
    • Organizer
      第57回日本リハビリテーション医学会学術集会,8月,京都
    • Related Report
      2020 Research-status Report
  • [Presentation] Sleep facilitation by Artificial carbonated bathing in healthy elderly: EEG, proximal and distal temperature evaluations.2020

    • Author(s)
      Uemura S, Kanbayashi T, Imanishi A, Terui Y, Satake M, Shioya T, Nishino S
    • Organizer
      SLEEP 2020, the 31th Annual Meeting of the Associated Professional Sleep Societies
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 簡易脳波と体温からみた人工炭酸泉浴による高齢者の睡眠促進効果2020

    • Author(s)
      上村佐知子、藤浦涼、石谷柊真、竹田有希、照井佳乃、佐竹將宏
    • Organizer
      第57回日本リハビリテーション医学会学術集会
    • Related Report
      2019 Research-status Report

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Published: 2019-04-18   Modified: 2025-01-30  

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