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Discrete mathematical approach for suitable coding scheme on DNA strorage

Research Project

Project/Area Number 19K11833
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Review Section Basic Section 60010:Theory of informatics-related
Research InstitutionNagaoka University of Technology (2021-2022)
Shonan Institute of Technology (2019-2020)

Principal Investigator

Manada Akiko  長岡技術科学大学, 工学研究科, 准教授 (20631138)

Co-Investigator(Kenkyū-buntansha) 太田 隆博  専修大学, ネットワーク情報学部, 教授 (60579001)
Project Period (FY) 2019-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2021: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2020: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
KeywordsDNAストレージ / グラフ理論 / データ系列制約 / キャパシティ / データ圧縮 / 制約符号 / バランス制約 / 連長制約 / 最大符号化率 / 部分系列の頻度 / 禁止語 / DNA / ラン長制約 / 離散数学 / データ保存・データ圧縮 / 符号化・復号 / 制約付き記号列
Outline of Research at the Start

DNA を用いた記録メディア(DNAストレージ)の「データの保存・読み出しコスト」や突然変異による「データの誤りや欠落」を考慮すべく,低コストで誤りなくデータの読み書き可能な手法を提案するための基礎的研究を行う.グラフ(点と線で物のつながりを表すモデル)を軸として,DNAストレージに適した符号の理論的解析とシミュレーションを行い,実用化に向けての礎を築く.

Outline of Final Research Achievements

DNA storage media, storage media consisting of DNA strands, are promising data storage media in the next generation from the perspective of ultra long lifespan and high density. On the other hand, “the low cost in reading/writing data” and “error robustness performances” are important issues, and suitable methods to approach these issues are highly demanded for the practical use of the media.
In this study, we proposed suitable coding schemes by concerning constraints on data sequences and data compression schemes. More precisely, we utilized the concepts of constrained coding and data compression based on circular strings, and evaluated their effectiveness.

Academic Significance and Societal Importance of the Research Achievements

DNAストレージの実用化に向けての「低コスト」かつ「信頼性」の観点から,主としてDNAの系列に関した研究成果をあげている.具体的には,DNAに適したデータ系列を考慮し,その系列にどのように符号化するか着目した成果である.つまり,系列の観点から「効率的に誤り耐性を持たせる」ことを論じているため,単体として使用した場合はもちろんのこと,ランダムに起きた誤りを修正する「誤り訂正」と融合させることで更なる有効性が期待できる.このような基礎的研究を基盤としてDNAストレージが実用化されれば,ビッグデータをコンパクトに保存することが現実的となり,社会的貢献は非常に高いと言える.

Report

(5 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (13 results)

All 2023 2022 2021 2020 2019

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (8 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results)

  • [Journal Article] A Necessary and Sufficient Condition for Reconstruction of Circular Binary String based on the Lengths of Substrings with Weights2022

    • Author(s)
      Takahiro OTA, Akiko MANADA
    • Journal Title

      Proceedings of International Symposium on Information Theory and Its Applications

      Volume: 0 Pages: 118-122

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The Maximum Run-Length Constrained Balanced Codes for Random-Access DNA Storage2022

    • Author(s)
      Akiko MANADA, Takahiro OTA, Hiroyoshi MORITA
    • Journal Title

      Proceedings of International Symposium on Information Theory and Its Applications

      Volume: 0 Pages: 123-127

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Addressing Information Using Data Hiding for DNA-based Storage Systems2020

    • Author(s)
      Takahiro Ota and Akiko Manada
    • Journal Title

      IEICE Proceeding Series

      Volume: 65 Pages: 509-513

    • DOI

      10.34385/proc.65.C07-1

    • NAID

      230000012705

    • ISSN
      2188-5079
    • Year and Date
      2020-10-18
    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Bonds of Constrained Systems and Their Characteristics2020

    • Author(s)
      Akiko Manada, Takahiro Ota and Hiroyoshi Morita
    • Journal Title

      IEICE Proceeding Series

      Volume: 65 Pages: 240-244

    • DOI

      10.34385/proc.65.B05-1

    • NAID

      230000012708

    • ISSN
      2188-5079
    • Year and Date
      2020-10-18
    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Compression by Substring Enumeration Using Sorted Contingency Tables2020

    • Author(s)
      Takahiro Ota, Hiroyoshi Morita, Akiko Manada
    • Journal Title

      IEICE Trans. Fundamentals

      Volume: Vol. E103-A, No. 6

    • NAID

      130007849972

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Presentation] q元連長制約符号に特化した特性方程式について2023

    • Author(s)
      安納 直毅, 眞田 亜紀子, 山内 陸, 太田 隆博
    • Organizer
      情報理論研究会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Introduction on Constrained Coding for DNA Storage2022

    • Author(s)
      Akiko MANADA
    • Organizer
      The 12th Vietnam Japan Scientific Exchange Meeting
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Graph Theoretical Reviews on Constrained Coding for Data Storage Media2022

    • Author(s)
      Akiko Manada
    • Organizer
      2022年電子情報通信学会総合大会 企画セッション
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] 反辞書符号化法における一意復号可能な重み付き部分列の十分条件2021

    • Author(s)
      太田隆博,眞田亜紀子
    • Organizer
      第44回情報理論とその応用シンポジウム
    • Related Report
      2021 Research-status Report
  • [Presentation] A survey on coding for DNA storage2020

    • Author(s)
      眞田亜紀子,太田隆博
    • Organizer
      第9回誤り訂正符号のワークショップ
    • Related Report
      2020 Research-status Report
  • [Presentation] On the Existence of Bonds for Constrained Systems2020

    • Author(s)
      Akiko Manada, Takahiro Ota, Hiroyoshi Morita
    • Organizer
      情報理論研究会
    • Related Report
      2019 Research-status Report
  • [Presentation] Maximum Sum-Rates of Input-Constrained Repeatable WOM Codes2019

    • Author(s)
      Akiko Manada, Takahiro Ota, Hiroyoshi Morita
    • Organizer
      第42回情報理論とその応用シンポジウム
    • Related Report
      2019 Research-status Report
  • [Presentation] DNAストレージのデータ圧縮に関する検討2019

    • Author(s)
      太田 隆博, 眞田 亜紀子
    • Organizer
      第42回情報理論とその応用シンポジウム
    • Related Report
      2019 Research-status Report

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Published: 2019-04-18   Modified: 2024-01-30  

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