| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2021: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
It was speculated that UVSs contained in cosmetics and sunscreen as an environmental factor for the pathogenesis of atopic dermatitis may be involved in the exacerbation of atopic dermatitis. In this study, we collected basic information on the skin toxicity evaluation of UVSs using skin allergy model mice for the effects of UVSs on immediate and delayed skin reactions in mice. As a result, it was suggested that some UVSs exacerbate or alleviate allergic reactions. It is expected that detailed analysis of this mechanism of action will provide information on the safety of UVSs contained in cosmetics.
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