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Neural basis of impairment of face recognition in children with attention-deficit/hyperactivity (ADHD)

Research Project

Project/Area Number 19K14492
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 10040:Experimental psychology-related
Research InstitutionNiigata University (2022)
Institute for Developmental Research Aichi Developmental Disability Center (2019-2021)

Principal Investigator

Kobayashi Megumi  新潟大学, 人文社会科学系, 准教授 (70781227)

Project Period (FY) 2019-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2021: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2020: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords顔認知 / 注意欠如・多動症 / 神経基盤 / 発達障害
Outline of Research at the Start

本研究では、学童期の注意欠如・多動症(Attention-Deficit/Hyperactivity Disorder: ADHD)における顔認知障害の神経基盤とその個人差を、脳活動計測によって実験的に検討する。特に、腹側経路の“顔の変化しない情報(人物)”の処理と背側経路の“顔の変化し得る情報(表情)”の処理に焦点を当て、ADHD児における顔処理の特性を明らかにする。

Outline of Final Research Achievements

The aim of this study was to examine the neural basis of disorders in face recognition in ADHD children by using non-invasive neuroimaging, functional NIRS. The most significant result was that we found that acute administration of MPH enhanced cortical processing of the left occipitotemporal area which is involved in face processing when ADHD children observed angry expressions. This result was published in the peer-reviewed international journal, Neurophotonics, in 2020. In addition, based on our studies, I published a review article in Japanese. Also, I was active in social contribution activities: for example, I gave some online lectures to the general public about visual processing in developmental disorders

Academic Significance and Societal Importance of the Research Achievements

最も大きな成果は、1つ目に幸福表情の処理においても、定型発達がSTSに依存するのと異なり、ADHDでは後頭葉顔領域の活動が優位になるという、非定型なパタンを示したことである。この結果は、これまで障害がないとされてきた表情においても、定型とは異なる見方をしている(手がかりや注目する情報が異なる)可能性を示唆するものである。2つ目は、治療薬(塩酸メチルフェニデート)の服薬によって怒り顔に対する後頭葉顔領域の脳活動が有意に上昇した点で、実行機能などの前頭葉の認知機能以外の脳内処理においても治療薬が奏効する可能性を示唆する。これらの知見は、ADHDに特有の視覚認知の理解の一助になると考えられる。

Report

(5 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (12 results)

All 2022 2021 2020 2019

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (10 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results)

  • [Journal Article] Acute administration of methylphenidate differentially affects cortial processing of emotional facial expressions in ADHD children as studied by functional near infrared spectroscopy.2020

    • Author(s)
      Kobayashi M, Ikeda T, Tokuda T, Monden Y, Nagashima M, Mizushima SG, Inoue T, Shimamura K, UjiieY, Arakawa A, Kuroiwa C, Ishijima M, Kishimoto Y, Kanazawa S, Yamagata T, Yamaguchi MK, Sakuta R, Dan I
    • Journal Title

      Neurophotonics

      Volume: Apr;7 Issue: 02 Pages: 025003-025003

    • DOI

      10.1117/1.nph.7.2.025003

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 顔処理の発達と障害ー近赤外分光法を用いた研究から2020

    • Author(s)
      小林恵
    • Journal Title

      ベビーサイエンス

      Volume: 20 Pages: 2-21

    • NAID

      40022595869

    • Related Report
      2020 Research-status Report
  • [Presentation] 表情認知の定型・非定型発達2022

    • Author(s)
      小林恵
    • Organizer
      日本赤ちゃん学会第22回学術集会
    • Related Report
      2022 Annual Research Report
  • [Presentation] The neural responses to bodies and faces in motion in infants' brain investigated by fNIRS.2021

    • Author(s)
      Megumi Kobayashi
    • Organizer
      日本赤ちゃん学会第21回学術集会
    • Related Report
      2021 Research-status Report
  • [Presentation] 乳児はカリカチュアから母親顔を認識できるか.2021

    • Author(s)
      小林恵
    • Organizer
      第26回日本顔学会大会(フォーラム顔学2021)
    • Related Report
      2021 Research-status Report
  • [Presentation] 身体処理の神経基盤の初期発達:顔処理との比較と倒立効果2021

    • Author(s)
      小林恵,O'Toole, Alice J.,金沢創,山口真美
    • Organizer
      日本基礎心理学会第40回大会
    • Related Report
      2021 Research-status Report
  • [Presentation] Spatial biases in infants' learning of serial order: evidence for the role of cultural experience2020

    • Author(s)
      Macchi Cassia, V., Shirai, N., Kobayashi, M., Arioli, M., Bulf, H., Yamaguchi, M. K.
    • Organizer
      International Congress of Infant Studies
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] Development of face processing in infancy2020

    • Author(s)
      Kobayashi, M.
    • Organizer
      Workshop- Dyadic interactions in a comparative perspective
    • Related Report
      2020 Research-status Report
  • [Presentation] The neural basis underlying impaired recognition of angry expression in ADHD children measured by near-infrared spectroscopy2019

    • Author(s)
      Kobayashi, M., Nagashima, M., Tokuda, T., Ikeda, T., Monden, Y., Kanazawa, S., Yamaguchi, M. K., Sakuta, R., Yamagata, T., & Dan. I.
    • Organizer
      Vision Sciences Society 19th Annual Meeting
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Identifying cortical area for processing of emotional facial expressions in ADHD children measured by near-infrared spectroscopy2019

    • Author(s)
      Kobayashi, M., Nagashima, M., Tokuda, T., Ikeda, T., Monden, Y., Kanazawa, S., Yamaguchi, M. K., Sakuta, R., Yamagata, T., & Dan, I.
    • Organizer
      15th Asia-Pacific Conference on Vision
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] fNIRSを用いた顔認知の発達と障害の検討2019

    • Author(s)
      小林恵
    • Organizer
      日本心理学会第83回大会
    • Related Report
      2019 Research-status Report
    • Invited
  • [Presentation] ADHD児童における表情認知の神経基盤-近赤外分光法による検討2019

    • Author(s)
      小林恵,池田尚広,徳田竜也,長嶋雅子,門田行史,金沢創,山口真美,作田亮一,山形崇倫,檀一平太
    • Organizer
      日本心理学会第83回大会
    • Related Report
      2019 Research-status Report

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Published: 2019-04-18   Modified: 2024-01-30  

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