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Brain mechanism for object recognition by audiovisual integration

Research Project

Project/Area Number 19K16192
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
Research InstitutionKanazawa Medical University

Principal Investigator

FURUYAMA TAKAFUMI  金沢医科大学, 医学部, 助教 (20802268)

Project Period (FY) 2019-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2021: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2020: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords視聴覚統合 / 光学計測 / クロスモーダル知覚
Outline of Research at the Start

本研究の目的は、視聴覚統合による物体認識に重要な脳内機構を解明することである。多くの動物は複数感覚から得た情報を脳内で統合し、周囲の環境を把握している。複数感覚の統合は、円滑なコミュニケーションや適切な物体認識に重要である。本研究では、動物を被験体として、視覚―聴覚間の神経回路を明らかにし、その神経活動を任意操作することで、視聴覚統合による物体認識行動にどのような変化を与えているかを明らかにしていく。

Outline of Final Research Achievements

The purpose of this study was to investigate the brain mechanisms for object recognition by audiovisual integration. In this study, optical and field potential measurement experiments in multiple regions were conducted in rodents and bats. The results revealed that the auditory cortex of bats was extensively activated by echolocation sounds. In contrast, in gerbils, the presentation of species-specific sounds did not alter the breadth of activity. Furthermore, the retinal map of bats was found to be similar to that of mice and gerbils. These results suggest that the basic information processing in vision is similar to that of other animals, but that there is specialization in the processing mechanism of echolocation sounds in the auditory cortex.

Academic Significance and Societal Importance of the Research Achievements

多感覚情報の統合機能は高次脳機能の1つであり、感覚統合の異常は自閉症などの発達障害に密接に関係している。特にヒトにおいて視聴覚統合は、音声と事物を対応させる言語発達に重要である。本研究では、広範囲の光学計測法を用いて、コウモリの基礎的な視覚情報処理機構およびエコーロケーションに特殊化した聴覚野の処理機構を明らかにした。今後、視覚野におけるエコーロケーション音の処理機構が明らかになることで、視聴覚統合による物体認識の生物学的基盤の解明だけでなく、ヒトの言語発達障害のメカニズム解明や治療法につながると期待される。

Report

(4 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (9 results)

All 2021 2020 2019

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (6 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] How frequency processing affects the sound-induced flash illusion?2020

    • Author(s)
      Yuki Ito, Yu Masago, Takafumi Furuyama, Kohta I. Kobayasi
    • Journal Title

      Acoustical Science and Technology

      Volume: 41 Issue: 1 Pages: 334-336

    • DOI

      10.1250/ast.41.334

    • NAID

      130007782664

    • ISSN
      0369-4232, 1346-3969, 1347-5177
    • Year and Date
      2020-01-01
    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Auditory cortical activity elicited by infrared laser irradiation from the outer ear in Mongolian gerbils.2020

    • Author(s)
      Tamai Y, Ito Y, Furuyama T, Horinouchi K, Murashima N, Michimoto I, Hishida R, Shibuki K, Hiryu S, Kobayasi KI
    • Journal Title

      PLoS One

      Volume: 15 Issue: 10 Pages: 1-13

    • DOI

      10.1371/journal.pone.0240227

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Serotonergic control of GABAergic inhibition in the lateral amygdala2020

    • Author(s)
      Yamamoto Ryo、Furuyama Takafumi、Sugai Tokio、Ono Munenori、Pare Denis、Kato Nobuo
    • Journal Title

      Journal of Neurophysiology

      Volume: 123 Issue: 2 Pages: 670-681

    • DOI

      10.1152/jn.00500.2019

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Activities of dopamine transporter positive neurons in the dorsal raphe region during the head-fixed fear conditioning2021

    • Author(s)
      Takafumi Furuyama, Ryo Yamamoto, Qin Zhao, Munenori Ono, and Nobuo Kato
    • Organizer
      動物心理学会 第81回大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 音圧レベルが恐怖条件づけ時の防御行動に及ぼす影響2021

    • Author(s)
      古山貴文,山本亮,小野宗範, 加藤伸郎
    • Organizer
      第68回 中部日本生理学会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 機能的に同定したマウス聴覚野サブ領野への聴覚視床を経由した2シナプス経路の可視化2020

    • Author(s)
      伊藤 哲史, 劉 麗, 古山 貴文, 小野 宗範
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 聴神経へのレーザー照射は聴覚知覚を生み出すか?2020

    • Author(s)
      玉井 湧太, 上中 望生, 伊藤 優樹, 兎田 幸司, 古山 貴文, 飛龍 志津子, 小林 耕太
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Research-status Report
  • [Presentation] MAP2遺伝子の欠損が聴覚に与える影響2020

    • Author(s)
      田中 一樹, 宮坂 知宏, 原田 彰宏, 伊藤 優樹, 古山 貴文, 小林 耕太
    • Organizer
      第43回日本神経科学大会
    • Related Report
      2020 Research-status Report
  • [Presentation] The selective response to communication sounds in auditory cortex of Mongolian gerbils2019

    • Author(s)
      Takafumi Furuyama, Taisei Minei, Rina Hayase, Kohta I Kobayasi
    • Organizer
      Neuro2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research

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Published: 2019-04-18   Modified: 2023-01-30  

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