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Genome-wide analysis on a hybrid gibbon population in the wild

Research Project

Project/Area Number 19K16240
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 45050:Physical anthropology-related
Research InstitutionKyoto University (2021-2022)
The University of Tokyo (2019-2020)

Principal Investigator

Matsudaira Kazunari  京都大学, アジア・アフリカ地域研究研究科, 研究員 (60813441)

Project Period (FY) 2019-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywordsテナガザル / 交雑 / 遺伝子浸透 / 類人猿進化 / 人類進化 / ゲノム
Outline of Research at the Start

ネアンデルタール人などの異なる人類集団との混血が、現生人類の進化に寄与してきたことが明らかになりつつある。本研究では、人類集団間の混血のモデルとして、一夫一妻の社会構造をつくり、現生類人猿で唯一、自然交雑が観察されているテナガザル、特にシロテテナガザルとボウシテナガザルの交雑集団を対象に、エクソーム解析(タンパク質コード領域のDNA塩基配列の網羅的解析)を行い、種間で異なるゲノム領域を明らかにする。加えて、現在、そして過去の種間交雑の様相と、交雑が両種のゲノム構成の進化に与えてきた影響を明らかにする。

Outline of Final Research Achievements

Phylogenetic relationship, divergence time, hybridization, and introgression of Hylobates gibbons were studied by GRAS-Di and whole genome sequencing analyses. The study revealed that the common ancestor of Hylobates species originated in the mainland of Southeast Asia, and the gibbons expanded their distribution to the Sunda islands with speciation. Introgression was detected between the many pairs of species including the species currently hybridizing in the wild, which suggested that Hylobates species have repeatedly experienced hybridization through their evolution.

Academic Significance and Societal Importance of the Research Achievements

ヒトに近縁な類人猿であるテナガザルの進化における交雑の様相の一端が解明されたことは、人類進化においける交雑・混血の様相の理解の一助になったと考えられる。今後、テナガザルについて更に詳細な研究を進めることで、人類進化の理解がより深まると考えられる。

Report

(5 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (1 results)

All 2021

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results)

  • [Journal Article] Divergence and introgression in small apes, the genus Hylobates, revealed by reduced representation sequencing2021

    • Author(s)
      Matsudaira, K. and Ishida, T.
    • Journal Title

      Heredity

      Volume: 127 Issue: 3 Pages: 312-322

    • DOI

      10.1038/s41437-021-00452-7

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access

URL: 

Published: 2019-04-18   Modified: 2024-01-30  

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