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3D dose measurement using Tailar-made scintillation detector

Research Project

Project/Area Number 19K17181
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 52040:Radiological sciences-related
Research InstitutionFujita Health University

Principal Investigator

Keisuke Yasui  藤田医科大学, 医療科学部, 講師 (50804514)

Project Period (FY) 2019-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2021: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords放射線計測 / 放射線治療 / 陽子線治療 / 治療計画 / 医学物理 / ガラス線量計 / CT再構成 / 線量計測 / 3Dプリンタ / 二次元検出器 / シンチレーション / 精度管理 / CCDカメラ
Outline of Research at the Start

本研究の目的は、患者個別の形状を再現したテーラーメイド型シンチレーション検出器の作成及びそれを利用した高精度な三次元線量計測の実現である。これまでの放射線がん治療における精度検証では、患者個々の形状による影響まで加味した高精度な三次元計測は実現されておらず、高精度化・個別化が進む医療において、新たな線量検証手法が必要とされている。本研究では、医療への応用が進む三次元造形プリンタに適応した放射線感受性の造形素材を開発し、三次元造形機能を活かした患者個々の形状の再現、シンチレーション光を利用した三次元計測と計測を基にした治療効果予測システムを構築する。

Outline of Final Research Achievements

In this study, we investigated the development of a three-dimensional dosimetry system using a 3D printer in order to realize the prediction of treatment effect based on the measured dose distribution.
We have developed a 3D printer-based dosimetry system using scintillation detector, and reported the results at the American Association of Physicists in Medicine (AAPM).
In the process of aiming at three-dimensional dosimetry and treatment effect prediction, we published the results of our research on the performance evaluation of glass dosimeters and two-dimensional detectors, and the results of our research using a treatment planning system in an English-language journal.

Academic Significance and Societal Importance of the Research Achievements

本研究期間を通じ、1)ガラス線量計を用いた陽子線の応答特性の検証、2)新型のダイオード二次元検出器の基礎性能特性の評価、3)前立腺がんの陽子線治療計画の堅牢性の評価、4)新たなCT再構成アルゴリズムの陽子線治療に対する有用性の検証、を主題として5編の英語論文を公開した。英語論文としての学術的意義に加え、これらの研究成果は放射線治療の発展に寄与し社会的意義もあるものと考えている。
また本研究で目標としていた三次元計測と治療経過予測については現在も検討を続けており、上記の研究成果がその基盤となるものである。

Report

(4 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (12 results)

All 2021 2020 2019 Other

All Journal Article (6 results) (of which Peer Reviewed: 6 results,  Open Access: 3 results) Presentation (5 results) (of which Int'l Joint Research: 1 results) Remarks (1 results)

  • [Journal Article] Evaluating the usefulness of the direct density reconstruction algorithm for intensity modulated and passively scattered proton therapy: Validation using an anthropomorphic phantom2021

    • Author(s)
      Yasui Keisuke、Muramatsu Rie、Kamomae Takeshi、Toshito Toshiyuki、Kawabata Fumitaka、Hayashi Naoki
    • Journal Title

      Physica Medica

      Volume: 92 Pages: 95-101

    • DOI

      10.1016/j.ejmp.2021.11.008

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dosimetric characterization of a new two-dimensional diode detector array used for stereotactic radiosurgery quality assurance2021

    • Author(s)
      Yasui K.、Saito Y.、Ogawa S.、Hayashi N.
    • Journal Title

      International Journal of Radiation Research

      Volume: 19 Issue: 2 Pages: 281-289

    • DOI

      10.52547/ijrr.19.2.5

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dosimetric effects of quality assurance-related setup errors in passive proton therapy for prostate cancer with and without a hydrogel spacer2021

    • Author(s)
      Omi Yuta、Yasui Keisuke、Shimomura Akira、Muramatsu Rie、Iwata Hiromitsu、Ogino Hiroyuki、Furukawa Akari、Hayashi Naoki
    • Journal Title

      Radiological Physics and Technology

      Volume: 14 Issue: 3 Pages: 328-335

    • DOI

      10.1007/s12194-021-00632-4

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of radiophotoluminescent glass dosimeter response for therapeutic spot scanning proton beam: suggestion of linear energy transfer‐based correction2021

    • Author(s)
      Nagata Junya、Yasui Keisuke、Omachi Chihiro、Toshiyuki Toshito、Shimizu Hidetoshi、Aoyama Takahiro、Hayashi Naoki
    • Journal Title

      Journal of Applied Clinical Medical Physics

      Volume: 22 Issue: 8 Pages: 265-272

    • DOI

      10.1002/acm2.13378

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dosimetric response of a glass dosimeter in proton beams: LET-dependence and correction factor2021

    • Author(s)
      Keisuke Yasui , Chihiro Omachi , Junya Nagata, Toshiyuki Toshito, Hidetoshi Shimizu,Takahiro Aoyama, Naoki Hayashi
    • Journal Title

      Physica Medica

      Volume: 81 Pages: 147-154

    • DOI

      10.1016/j.ejmp.2020.12.001

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Periodic Measurements of Passive Proton Beam Width Using Radiochromic Film in Fixed Gantry System2019

    • Author(s)
      Shimozato Tomohiro、Yasui Keisuke、Kinou Hireto、Komatsu Fumiaki
    • Journal Title

      International Journal of Medical Physics, Clinical Engineering and Radiation Oncology

      Volume: 08 Issue: 04 Pages: 193-203

    • DOI

      10.4236/ijmpcero.2019.84017

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Feasibility study of 3D-printed scintillation detector for quality assurance2020

    • Author(s)
      Keisuke Yasui
    • Organizer
      2020 Joint AAPM | COMP Meeting
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] 三次元プリンタを用いたシンチレーション検出器の開発2020

    • Author(s)
      安井啓祐、齊藤泰紀、寺倉万結、櫟原誠也、小川柊太、林直樹
    • Organizer
      第36回日本診療放射線技師学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 新型二次元ダイオード検出器の線量特性の検証2019

    • Author(s)
      安井啓祐、齊藤泰紀、小川柊太、林直樹
    • Organizer
      第12回中部放射線医療技術学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] Impact of Spot Position Errors for Three Optimization Algorithms in Spot Scanning Proton Therapy2019

    • Author(s)
      Y Omi, N Hayashi, A Shimomura, K Yasui, T Nakanishi
    • Organizer
      61st AAPM Annual Meeting
    • Related Report
      2019 Research-status Report
  • [Presentation] 3Dプリンタを用いたシンチレーション検出器作成に関する基礎検討2019

    • Author(s)
      寺倉万結、安井啓祐、齊藤泰紀、小川柊太、櫟原誠也
    • Organizer
      第12回中部放射線医療技術学術大会
    • Related Report
      2019 Research-status Report
  • [Remarks] 研究紹介HP

    • URL

      http://info.fujita-hu.ac.jp/~k-yasui/news.html

    • Related Report
      2019 Research-status Report

URL: 

Published: 2019-04-18   Modified: 2023-01-30  

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