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Development of sealed radioactive phantoms for PET system QA/QC

Research Project

Project/Area Number 19K17185
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 52040:Radiological sciences-related
Research InstitutionNational Institutes for Quantum and Radiological Science and Technology

Principal Investigator

Akamatsu Go  国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所 先進核医学基盤研究部, 研究員(任常) (00726557)

Project Period (FY) 2019-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2019: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
KeywordsPET / ファントム / 密封放射線源 / 核医学 / QA/QC / 放射線 / Na-22
Outline of Research at the Start

これまでにない形状(例えば中空ドーム型、柔軟なチューブ型、円柱多孔型)に半減期が比較的長い放射線源(例えば22Na)を密封することにより、PET装置品質保証・品質管理(QA/QC)用の新しいファントムの開発を目指す。上記ファントムを開発できれば、(1)いつでもどこでも誰でも同じようにPET装置のQA/QCができるようになり、利便性と再現性が飛躍的に向上する(2)円筒形状ではない次世代のPET装置にも適用できる任意形状のファントム製作が可能になる(3)開発したファントムを製品化することにより、核医学分野(PET/SPECT)のみならず、他分野(例えば放射線計測分野)への応用も期待できる。

Outline of Final Research Achievements

We have developed novel-shape sealed radioactive (Na-22) phantoms for PET system quality assurance and quality control (QA/QC). The phantoms showed good uniformity of radioactivity distributions and enough stability for PET system evaluation. They enable us to evaluate and calibrate PET systems without radioactive solutions.

Academic Significance and Societal Importance of the Research Achievements

液体状の放射線源を手動で封入する(従来方法)必要がなくなり、いつでもどこでも誰でも同じようにPET装置の品質管理・品質保証(QA/QC)ができるようになった。PET用放射線検出器の評価検証にも応用でき、次世代核医学イメージング装置の研究開発を加速することができた。

Report

(3 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • Research Products

    (4 results)

All 2021 2020 2019

All Journal Article (2 results) (of which Peer Reviewed: 1 results) Presentation (2 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] First imaging demonstration of a crosshair light-sharing PET detector2021

    • Author(s)
      Yoshida Eiji、Akamatsu Go、Tashima Hideaki、Kamada Kei、Yoshikawa Akira、Yamaya Taiga
    • Journal Title

      Physics in Medicine & Biology

      Volume: 66 Issue: 6 Pages: 065013-065013

    • DOI

      10.1088/1361-6560/abe839

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Development of sealed 22Na phantoms for PET system QA/QC: uniformity and stability evaluation2020

    • Author(s)
      Go Akamatsu, Eiji Yoshida, Takahiro Mikamoto, Takamasa Maeda, Hidekatsu Wakizaka, Hideaki Tashima, Yuichiro Wakitani, Mikio Matsumoto, Taiga Yamaya
    • Journal Title

      2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)

      Volume: 2019 Pages: 1-3

    • DOI

      10.1109/nss/mic42101.2019.9059761

    • Related Report
      2020 Annual Research Report
  • [Presentation] Initial evaluation of novel shape radioactive sample sources with 22Na and 68Ge2019

    • Author(s)
      Go Akamatsu, Eiji Yoshida, Takamasa Maeda, Hidekatsu Wakizaka, Hideaki Tashima, Takahiro Mikamoto, Taiga Yamaya
    • Organizer
      第75回日本放射線技術学会総会学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] Development of sealed 22Na phantoms for PET system QA/QC: uniformity and stability evaluation2019

    • Author(s)
      Go Akamatsu, Eiji Yoshida, Takahiro Mikamoto, Takamasa Maeda, Hidekatsu Wakizaka, Hideaki Tashima, Yuichiro Wakitani, Mikio Matsumoto, Taiga Yamaya
    • Organizer
      2019 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC)
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research

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Published: 2019-04-18   Modified: 2022-01-27  

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