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Exploring the mechanism of oral and systemic health disparities caused by socioeconomic factors

Research Project

Project/Area Number 19K19312
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 57080:Social dentistry-related
Research InstitutionKyoto University

Principal Investigator

Asai Keita  京都大学, 医学研究科, 客員研究員 (10646376)

Project Period (FY) 2019-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2021: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordseducational attainment / number of missing teeth / depressive symptoms / 教育歴 / 喪失歯数 / 全身疾患 / 心不全 / BNP / 歯周病 / 抑うつ状態 / 社会経済因子 / 口腔清掃習慣 / 歯周疾患 / 健康格差
Outline of Research at the Start

今回の研究の目的は、口腔の健康格差が、社会経済因子にともなう健康リテラシー行動を、どの様に介して全身疾患に結びついているのかを、約1万人規模のながはまコホート事業のデータを用いて統計学的に解析し、臨床や政策に応用出来るエビデンスをつくることである。今回の研究の目的は、口腔の健康格差が、社会経済因子にともなう健康リテラシー行動を、どの様に介して全身疾患に結びついているのかを、約1万人規模のながはまコホート事業のデータを用いて統計学的に解析し、臨床や政策に応用出来るエビデンスをつくることである。

Outline of Final Research Achievements

The purpose of this study was to clarify the independent and interactive effects of educational attainment and depressive symptoms on the number of tooth loss. We collected cross-sectional data from 9,647 individuals from the Japanese general population. Multivariate analysis identified educational attainment as an independent determinant of tooth loss. Analyzes including an interaction term revealed that the relationship between educational history and the number of missing teeth varied with depressive symptoms, indicating a positive interaction. This study suggests the existence of a significant association between educational history and tooth loss, and the existence of a correlation between '9 years or less of educational history' and 'depressive symptoms'. In addition, we also showed that low educational attainment, especially among women, is significantly associated with the number of missing teeth.

Academic Significance and Societal Importance of the Research Achievements

今回の結果は、歯を失うリスクの高いグループに口腔ケアの指導を行うことの重要性を示唆している。 また、臨床的対策として、歯科医と精神科医の相互理解の必要性が挙げられる。 2者間のより緊密な連携は、抑うつ症状や不安、および/または口腔衛生の知識の欠如のために十分な口腔ケアが出来なかったり歯科医院へ通院出来ない患者の障壁を取り除くために重要である。さらに、本研究は歯の喪失のハイリスクグループの口腔リテラシーを高めるための政策に役立つと考えられる。

Report

(5 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (3 results)

All 2021 2020

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (1 results)

  • [Journal Article] Association Between Tooth Loss and Longitudinal Changes in B-Type Natriuretic Peptide Over 5 Years in Postmenopausal Women: The Nagahama Study2021

    • Author(s)
      Fukuhara Shizuko、Asai Keita、Fukuhara Takehisa、Kakeno Asumi、Yamanaka Shigeki、Nakao Kazumasa、Watanabe Takuma、Takahashi Katsu、Yamazaki Toru、Umebachi Chisa、Kashiwagi Marina、Setoh Kazuya、Kawaguchi Takahisa、Tabara Yasuharu、Morita Satoshi、Nakayama Takeo、Matsuda Fumihiko、Nakao Kazuwa、Bessho Kazuhisa
    • Journal Title

      Current Problems in Cardiology

      Volume: - Issue: 10 Pages: 100997-100997

    • DOI

      10.1016/j.cpcardiol.2021.100997

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of Education and Depressive Symptoms with Tooth Loss2020

    • Author(s)
      Fukuhara S.、Asai K.、Kakeno A.、Umebachi C.、Yamanaka S.、Watanabe T.、Yamazaki T.、Nakao K.、Setoh K.、Kawaguchi T.、Morita S.、Nakayama T.、Matsuda F.、Bessho K.、Tabara Yasuharu、Kawaguchi Takahisa、Setoh Kazuya、Takahashi Yoshimitsu、Kosugi Shinji、Nakayama Takeo、Matsuda Fumihiko
    • Journal Title

      Journal of Dental Research

      Volume: 100 Issue: 4 Pages: 361-368

    • DOI

      10.1177/0022034520969129

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 血漿B型ナトリウム利尿ペプチド値と喪失歯数の関連についてのコホート研究2021

    • Author(s)
      福原紫津子、浅井啓太、中尾一祐、別所和久
    • Organizer
      第66回 日本口腔外科学会総会
    • Related Report
      2021 Research-status Report

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Published: 2019-04-18   Modified: 2024-01-30  

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