| Project/Area Number |
19K19338
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 57080:Social dentistry-related
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| Research Institution | Kanagawa Dental College |
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Principal Investigator |
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| Project Period (FY) |
2019-04-01 – 2024-03-31
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| Project Status |
Completed (Fiscal Year 2023)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2021: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2020: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2019: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 歯周病 / 糖尿病 / 心血管疾患 |
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| Outline of Research at the Start |
本研究では，糖尿病の人が、糖尿病でない人に比べて歯周病が重度であるかどうかを調べます。また、糖尿病の人において歯周病が重症化する原因を調べます。さらに、糖尿病の人において、歯周病が重症であると心筋梗塞や脳梗塞がおこりやすいかどうかを調べます。
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| Outline of Final Research Achievements |
Significant associations with periodontal indices were found in patients with type 1 and type 2 diabetes, placing type 1 diabetics in between non-diabetics and type 2 diabetics. In addition, significant differences in periodontal disease indices, particularly in the rates of deep periodontal pockets, deep periodontal pocket sites, and upset tooth rates, were suggested in patients with diabetes mellitus.
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| Academic Significance and Societal Importance of the Research Achievements |
2型糖尿病と非糖尿病の歯周組織の状態の比較は多く報告されているが、日本における1型糖尿病の情報は少ない。本研究を行ったことで1型・２型糖尿病患者の歯周組織の現状を把握し、歯周病治療，あるいは歯周病予防を行うことで糖尿病や心血管疾患といった全身疾患の予防、QOL向上に寄与できる可能性がある。
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