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Understanding muscle-tendon architecture and function in-vivo human

Research Project

Project/Area Number 19K19998
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 59020:Sports sciences-related
Research InstitutionNiigata University (2022-2023)
Osaka University of Health and Sport Sciences (2019-2020)

Principal Investigator

Kunimasa Yoko  新潟大学, 人文社会科学系, 助教 (20804355)

Project Period (FY) 2021-11-01 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2021: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2020: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords筋代謝 / 筋機能 / 近赤外線分光法 / NIRS / 皮膚血流 / 骨格筋 / 筋酸素動態 / 効率 / TRS-NIRS / CW-NIRS / 超音波 / 筋構造 / 走運動 / ランニングエコノミー / 筋腱複合体 / 筋酸素飽和度 / 弾性利用 / 生体データ / 運動効率 / 弾性
Outline of Research at the Start

これまでに約6000名のヒト生体ビッグデータを構築し、同一種のヒト内においても身体運動能力の異なる母集団によって多様な骨格・筋腱の形態的特徴が存在することを明らかにしてきた。本研究では、これらの知見を発展させ、特徴的な形態を有するヒトの身体運動中の筋の力発揮効率や弾性利用を明らかにすることで、骨格・筋腱の形態的特徴と身体運動中の機能との関係を検討していく。

Outline of Final Research Achievements

The initial objective of this study was to investigate the relationship between specific muscle-tendon architecture and their function during human movement. However, some problems arose that were not anticipated in the original plan in the muscle metabolism evaluation method, which is necessary for clarifying the relationship between skeletal and muscle tendon morphology and muscle force production and metabolic characteristics during movement. Therefore, we developed a method to evaluate muscle oxygenation and deoxygenation during exercise by using both a noninvasive skin vasoconstrictor transcutaneous administration and a near-infrared spectroscopy (TRS-NIRS) that can measure absolute and relative values of muscle oxygenation and deoxygenation.

Academic Significance and Societal Importance of the Research Achievements

本研究で開発された皮膚血流の影響を受けない筋酸素化・脱酸素化評価法によって,安静時だけでなく運動時や暑熱環境下等の熱ストレスが加わる状況においても筋代謝を評価することができるようになった.これによって,これまで困難であった様々な環境下,条件下での運動中の筋の生理学的機能評価が筋間や個人間で比較できるようになり,今後の筋機能研究に大いに貢献することが期待できる.

Report

(5 results)
  • 2023 Annual Research Report   Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2020 Annual Research Report
  • 2019 Research-status Report
  • Research Products

    (14 results)

All 2024 2023 2021 2020 2019 Other

All Int'l Joint Research (1 results) Journal Article (4 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 4 results,  Open Access: 4 results) Presentation (8 results) (of which Int'l Joint Research: 5 results) Remarks (1 results)

  • [Int'l Joint Research] Aix-Marseille University(フランス)

    • Related Report
      2023 Annual Research Report
  • [Journal Article] Is the muscle-tendon architecture of non-athletic Kenyans different from that of Japanese and French males?2023

    • Author(s)
      Kunimasa Y. Sano K, Nicol C, Barthelemy J, Ishikawa M
    • Journal Title

      Journal of Physiological Anthropology

      Volume: 42 Issue: 1 Pages: 9-9

    • DOI

      10.1186/s40101-023-00326-3

    • Related Report
      2023 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Sex Influence on the Functional Recovery Pattern After a Graded Running Race: Original Analysis to Identify the Recovery Profiles2021

    • Author(s)
      Macchi Robin、Vercruyssen Fabrice、Hays Arnaud、Aubert Gaetan、Exubis Gaetan、Chavet Pascale、Goubert Emmanuelle、Souron Robin、Kunimasa Yoko、Nicol Caroline
    • Journal Title

      Frontiers in Physiology

      Volume: 12

    • DOI

      10.3389/fphys.2021.649396

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Lower complexity of motor primitives ensures robust control of high-speed human locomotion2020

    • Author(s)
      Santuz Alessandro、Ekizos Antonis、Kunimasa Yoko、Kijima Kota、Ishikawa Masaki、Arampatzis Adamantios
    • Journal Title

      Heliyon

      Volume: 6 Issue: 10 Pages: e05377-e05377

    • DOI

      10.1016/j.heliyon.2020.e05377

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Limb-Specific Features and Asymmetry of Nerve Conduction Velocity and Nerve Trunk Size in Human2020

    • Author(s)
      Nobue Ayaka、Kunimasa Yoko、Tsuneishi Hiromu、Sano Kanae、Oda Hiroyuki、Ishikawa Masaki
    • Journal Title

      Frontiers in Physiology

      Volume: 11 Pages: 1-9

    • DOI

      10.3389/fphys.2020.609006

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Cutaneous blood flow modulates assessments of muscle oxygenations: comparisons of continuous-wave and time-resolved near-infrared spectroscopy.2024

    • Author(s)
      Kunimasa Y, Amano T, Okushima D, Koga S.
    • Organizer
      29th annual Congress of the European College of Sport Science
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Reliability of ultrasound-based muscle cross-sectional area in lower-limb: A comparative analysis between ultrasound and MRI.2023

    • Author(s)
      Kunimasa Y, Macchi R, Corcelle, Michel CP, Hostin MA, Bendahan D, Nicol C.
    • Organizer
      XXIX Congress of the International Society of Biomechanics
    • Related Report
      2023 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Application of assisted sprint with and without assisted loads.2020

    • Author(s)
      Tsuneishi H, Ohashi R, Kitano Y, Kunimasa Y, Okamoto T, Hirashima, Kijima, Ngahara R, Ishikawa M.
    • Organizer
      25th annual Congress of the European College of Sport Science
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Lower complexity of motor primitives ensures robust control of high-speed human locomotion.2020

    • Author(s)
      Santuz A, Ekizos A, Kunimasa Y, Kijima K, Ishikawa M, Arampatzis A.
    • Organizer
      25th annual Congress of the European College of Sport Science
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Neuromechanical modulation during bilateral hopping in patients with unilateral Achilles tendon rupture2019

    • Author(s)
      Ishikawa M, Oda H, Sano K, Kunimasa Y
    • Organizer
      XXVII Congress of the International Society of Biomechanics
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Characteristics of lower limb tendons and their relationships with the javelin throw performance2019

    • Author(s)
      Kunimasa Y, Iwasaki M, Ishikawa M
    • Organizer
      24th annual Congress of the European College of Sport Science
    • Related Report
      2019 Research-status Report
  • [Presentation] Characteristics of sprint running with the horizontal resisted loads2019

    • Author(s)
      Kitano Y, Makino A, Arai A, Kunimasa Y, Sano K, Ishikawa M
    • Organizer
      24th annual Congress of the European College of Sport Science
    • Related Report
      2019 Research-status Report
  • [Presentation] Mechanics of effective propulsion movements for the wheelchair sprint start2019

    • Author(s)
      Kijima K, Kishizawa H, Kataoka S, Kunimasa Y, Makino A, Ishikawa M, Ito A
    • Organizer
      24th annual Congress of the European College of Sport Science
    • Related Report
      2019 Research-status Report
  • [Remarks] 研究室HP

    • URL

      https://yokokunimasa.wixsite.com/kunimasa-lab

    • Related Report
      2023 Annual Research Report

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Published: 2019-04-18   Modified: 2025-01-30  

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