Evaluation of Potential Role of Olive Leaf Extract as A Natural Way to Prevent and Improve Anemia: A randomized Clinical Trial in Japan and Tunisia
Project/Area Number |
19K20106
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Research Category |
Grant-in-Aid for Early-Career Scientists
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Allocation Type | Multi-year Fund |
Review Section |
Basic Section 59040:Nutrition science and health science-related
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Research Institution | University of Tsukuba |
Principal Investigator |
FERDOUSI FARHANA 筑波大学, 地中海・北アフリカ研究センター, 主任研究員 (80820927)
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Project Period (FY) |
2019-04-01 – 2024-03-31
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Project Status |
Granted (Fiscal Year 2022)
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Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2021: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2020: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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Keywords | Olive leaf extract / Anemia / Hemoglobin / Natural compound / anemia / hematological parameter / hemoglobin / Olive leaf tea / Clinical trial |
Outline of Research at the Start |
A randomized controlled trial will be conducted in Japan and Tunisia to evaluate the effect of long term consumption of olive leaf tea on hematological parameters in apparently healthy young adults and elderly with mild or borderline anemia.
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Outline of Annual Research Achievements |
Total 333 participants have been assessed for eligibility for the olive leaf extract intervention study. Among them 273 were qualified for baseline hematological assessment. Finally, 165 participants were randomized in three groups, including one placebo and two intervention groups. Total 157 participants completed 12-weeks of intervention.
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Current Status of Research Progress |
Current Status of Research Progress
1: Research has progressed more than it was originally planned.
Reason
Clinical trial has been completed for 165 study participants. All laboratory investigation data have been received.
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Strategy for Future Research Activity |
All data regarding the study have been received. Data cleaning and management are ongoing. After completeing the data analysis, results will be submitted to a high impact journal and will be presented at national/international conferences.
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Report
(4 results)
Research Products
(16 results)
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[Presentation] Effects of Oral Intake of Olive Leaf Extract on Hematological Parameters: A Double-Blinded, Randomized, Placebo-Controlled Trial in Progress2022
Author(s)
Farhana Ferdousi, Masud Alam, Risa Araki, Sofya Suidasari, Miki Yokozawa, Ken Yamauchi, Koichi Hashimoto, Rashidul Haque, Hiroko Isoda
Organizer
The 63rd American Society of Hematology Annual Meeting
Related Report
Int'l Joint Research
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