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Research to investigate the effect of skeletal muscle pump action on edema development using a new quantitative evaluation method

Research Project

Project/Area Number 19K20169
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 59040:Nutrition science and health science-related
Research InstitutionReiwa Heath Sciences University (2022)
Nishikyushu University (2019-2021)

Principal Investigator

Kogo Haruki  令和健康科学大学, リハビリテーション学部, 教授 (90640821)

Project Period (FY) 2019-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2021: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords浮腫 / 圧痕深度 / 皮膚微小循環血流量 / 再灌流圧 / 水分量 / 皮膚微小循環血流 / 骨格筋ポンプ作用 / 定量的評価法 / 微小循環血流量 / 脳卒中
Outline of Research at the Start

むくみ(浮腫)発生の危険因子として,筋のポンプ機能低下が影響していることを明らかにするために,浮腫の圧痕の深さ,静脈還流量・還流速度,および毛細血管の血流量を指標として評価する研究である.
被験者に足関節の筋収縮運動を約2秒間で上げ下げする速さで,1回(10分間)/日,5日/週,1ヶ月間行わせて,筋収縮運動直後・1ヶ月後・2ヶ月後・3ヶ月後を横断的・縦断的に調査する.

Outline of Final Research Achievements

In this study, we investigated the depth of indentation of edema by a new edema gauge method, skin blood flow rate by laser The aim was to examine perfusion pressure and body composition by the Inbody as indicators.
The cutoff value for distinguishing the presence or absence of edema was determined by the edema gauge method, and it was clarified that the edema indentation depth was 2.25 mm.
In addition, we investigated exercise habits, measured body composition, and cutaneous microcirculatory blood flow, and investigated the factors that exercise habits have, and found that they affect body fat thickness. In addition, body water content and cutaneous microcirculatory blood flow, which are closely related to edema, were not related to exercise habits.

Academic Significance and Societal Importance of the Research Achievements

浮腫を呈する疾患としては,心疾患,腎疾患,内分泌疾患,肝疾患の内部疾患から,脳卒中,整形外科疾患,悪性腫瘍など多岐にわたっているが,浮腫は日常生活の場面においても見られる身体症状の一つである.浮腫の発生機序として静脈がうっ滞している場合があるが,静脈うっ滞が起こる要因には不動があり,不動は深部静脈血栓や肺塞栓症の危険因子にもなる.しかしながら,浮腫は不明な点が多く,コンセンサスが得られていないため,浮腫発生における筋の静脈ポンプ低下の影響を解明することは社会的意義がある.さらに,浮腫有無を識別するカットオフ値を明らかにすることは学術的意義が大きいと思われる.

Report

(5 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (2 results)

All 2022 2020

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results)

  • [Journal Article] Associations of Exercise Habits and Circulatory Dynamics with Peripheral Lower Limb Body Composition in Healthy Community-dwelling Older Individuals2022

    • Author(s)
      Kogo H, Yamashita Y, Murata J
    • Journal Title

      Journal of Community Medicine and Health Solutions

      Volume: 3 Issue: 1 Pages: 27-34

    • DOI

      10.29328/journal.jcmhs.1001017

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 圧痕性浮腫の病態を識別する圧痕深度評価法におけるカットオフ値2020

    • Author(s)
      古後晴基,山下裕,村田伸,鳥山海樹,村田潤,東登志夫
    • Journal Title

      ヘルスプロモーション理学療法研究

      Volume: 10 Pages: 55-60

    • NAID

      130007884562

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access

URL: 

Published: 2019-04-18   Modified: 2024-01-30  

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