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Theoretical research on spatiotemporal information processing in the brain

Research Project

Project/Area Number 19K20365
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 61040:Soft computing-related
Research InstitutionThe University of Tokyo (2021-2022)
Institute of Physical and Chemical Research (2019-2020)

Principal Investigator

Terada Yu  東京大学, 大学院理学系研究科(理学部), 客員共同研究員 (40815338)

Project Period (FY) 2019-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2022: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2021: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Keywordsリカレントニューラルネットワーク / 神経データ / 結合推定 / 非線形動力学 / カオス / ニューラルネットワーク / 平均場理論 / 位相振動子系 / 線形応答理論 / 神経ゆらぎ / ベイズ計算 / アトラクターニューラルネットワーク / 場の理論 / 格子細胞 / 場所細胞 / 理論神経科学 / 嗅内皮質 / 学習 / 海馬
Outline of Research at the Start

脳神経系が行っている時空間情報処理のメカニズムを数理的に解明することを目指し,リズムの観点を取り入れた数理モデルを用いて理論解析を行う.具体的には,海馬における場所細胞や嗅内皮質における格子細胞といった神経細胞が示す固有のダイナミクスをうまく表現する位相縮約に基づく位相モデルや発火率モデルを構築する.そしてそれら結合系が示すダイナミクスを解析し,計算能力を評価し,ダイナミクスと情報処理能力の関係を調べる.リズムと乱雑な活動が共存する系に記憶容量や時空間に関するタスクを行わせることで,リズムの持つ計算論的役割を明らかにする.実データとの整合性も取りながら理論研究を進めていく.

Outline of Final Research Achievements

In this research project, we develop statistical inference methods for reconstrcucting neuronal couplings from spiking data and study theoretical/computational models for neural dynamics and computations. Our methods were shown to exhibit high accuracny and efficiency in inferring synaptic couplings. We also bulit a linear response theory in coupled oscillators to study the properties of macroscopic and mesoscopic activity in the brain.We applied the theory to develop an inference method in coupled oscillators. Finally, we study the computational roles of deterministic activity in neural networks and demonstrated that the choatic neural activity may serve as a neural substrate for reprepsentations of probability distributions.

Academic Significance and Societal Importance of the Research Achievements

提案した結合推定手法は現状得られているデータだけでなく今後得られるよりサイズの大きいデータに対しても適用が期待される.神経回路網のモデルは神経科学の問題だけでなく,機械学習やAIといった関連分野への波及効果も期待できる.

Report

(5 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (22 results)

All 2023 2022 2021 2020 2019 Other

All Int'l Joint Research (9 results) Journal Article (3 results) (of which Peer Reviewed: 3 results,  Open Access: 3 results) Presentation (9 results) (of which Int'l Joint Research: 4 results,  Invited: 1 results) Book (1 results)

  • [Int'l Joint Research] カリフォルニア大学サンディエゴ校(米国)

    • Related Report
      2022 Annual Research Report
  • [Int'l Joint Research] ノルウェー科学技術大学(ノルウェー)

    • Related Report
      2021 Research-status Report
  • [Int'l Joint Research] コペンハーゲン大学(デンマーク)

    • Related Report
      2021 Research-status Report
  • [Int'l Joint Research] ペンシルベニア大学(米国)

    • Related Report
      2021 Research-status Report
  • [Int'l Joint Research] ノルウェー科学技術大学(ノルウェー)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] コペンハーゲン大学(デンマーク)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] ペンシルベニア大学(米国)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] ノルウェー科学技術大学(ノルウェー)

    • Related Report
      2019 Research-status Report
  • [Int'l Joint Research] コペンハーゲン大学(デンマーク)

    • Related Report
      2019 Research-status Report
  • [Journal Article] Inferring Neuronal Couplings From Spiking Data Using a Systematic Procedure With a Statistical Criterion2020

    • Author(s)
      Terada Yu、Obuchi Tomoyuki、Isomura Takuya、Kabashima Yoshiyuki
    • Journal Title

      Neural Computation

      Volume: 32 Issue: 11 Pages: 2187-2211

    • DOI

      10.1162/neco_a_01324

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Linear response theory for coupled phase oscillators with general coupling functions2020

    • Author(s)
      Y. Terada and Y. Y. Yamaguchi
    • Journal Title

      Journal of Physics A: Mathematical and Theoretical

      Volume: 53 Issue: 4 Pages: 044001-044001

    • DOI

      10.1088/1751-8121/ab5eaf

    • NAID

      120006778256

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Objective and efficient inference for couplings in neuronal network2019

    • Author(s)
      Terada Yu、Obuchi Tomoyuki、Isomura Takuya、Kabashima Yoshiyuki
    • Journal Title

      Journal of Statistical Mechanics: Theory and Experiment

      Volume: 2019 Issue: 12 Pages: 124010-124010

    • DOI

      10.1088/1742-5468/ab3219

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Stable coding in gated recurrent neural networks2023

    • Author(s)
      Yu Terada, Johnatan Aljadeff
    • Organizer
      COSYNE 2023
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 確率計算におけるカオス的な神経活動の役割2022

    • Author(s)
      寺田裕,豊泉太郎
    • Organizer
      NEURO 2022
    • Related Report
      2022 Annual Research Report
  • [Presentation] Chaotic neural dynamics facilitate representations for probabilistic computation through their intrinsic variability,2022

    • Author(s)
      Yu Terada, Taro Toyoizumi
    • Organizer
      Neuroscience 2022
    • Related Report
      2022 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 多点同時計測データからの結合の統計的推定法と神経データへの適用2021

    • Author(s)
      寺田裕
    • Organizer
      第13回 数理モデリング研究会 on Zoom: Workshop on multitrack event-trains in neural, social, seismological, and financial data
    • Related Report
      2021 Research-status Report
    • Invited
  • [Presentation] ニューラルネットにおける短期記憶の1ビット圧縮センシングによる想起2021

    • Author(s)
      杉崎 嵐,寺田 裕,小渕 智之,樺島 祥介
    • Organizer
      日本物理学会第76回年次大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 決定論的な神経ゆらぎを用いて確率的計算を行う神経回路網モデル2021

    • Author(s)
      寺田 裕,豊泉 太郎
    • Organizer
      日本物理学会第76回年次大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 内部ダイナミクスを探索に用いて学習を行うリカレントニューラルネットワーク2020

    • Author(s)
      寺田裕,豊泉太郎
    • Organizer
      日本物理学会 第75回年次大会
    • Related Report
      2019 Research-status Report
  • [Presentation] Objective and efficient inference for couplings in neuronal networks2019

    • Author(s)
      Terada Yu、Obuchi Tomoyuki、Isomura Takuya、Kabashima Yoshiyuki
    • Organizer
      Statistical Physics and Neural Computation (SPNC-2019)
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Objective and efficient inference for couplings in neuronal networks2019

    • Author(s)
      Terada Yu、Obuchi Tomoyuki、Isomura Takuya、Kabashima Yoshiyuki
    • Organizer
      40 years of Replica Symmetry Breaking (RSB40)
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Book] ニューラルネットワークとディープラーニング2022

    • Author(s)
      Charu C. Aggarwal、竹村 彰通、今泉 允聡、李 鍾賛、今井 貴史、今井 徹、紅林 亘、齋藤 邦彦、健山 智子、寺田 裕、西出 俊、西出 亮
    • Total Pages
      520
    • Publisher
      学術図書出版社
    • ISBN
      9784780607147
    • Related Report
      2022 Annual Research Report

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Published: 2019-04-18   Modified: 2024-01-30  

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