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In-situ analysis of ultra-stable fluorescent nanoparticles confined in nanoscale structures

Research Project

Project/Area Number 19K21935
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Review Section Medium-sized Section 19:Fluid engineering, thermal engineering, and related fields
Research InstitutionOkayama University (2021)
Osaka City University (2019-2020)

Principal Investigator

Fujiwara Masazumi  岡山大学, 学術研究院自然科学学域, 研究教授 (30540190)

Co-Investigator(Kenkyū-buntansha) 遠藤 達郎  大阪府立大学, 工学(系)研究科(研究院), 准教授 (40432017)
Project Period (FY) 2019-06-28 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2020: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2019: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Keywords蛍光ナノダイヤモンド / ブラウン運動 / 流体力学 / ナノ流路 / 量子センシング / ナノ流体 / フォトニック結晶
Outline of Research at the Start

本研究では、バルク流体力学が適用不可能なナノスケールでの流体挙動を、プローブナノ粒子を用いてその場でリアルタイムに観測する事で、これまで観測が困難であったナノ空間中の流体挙動を実験的に明らかにする事を目的とする。そのために、代表者らが実現した蛍光ダイヤモンドナノ粒子の並進、および、回転ブラウン運動計測を、脂質二重膜でシールしたナノ細孔中の粒子に適用して、ナノスケールの流体挙動を計測する技術を確立する。本手法は、これまで有効な手法が乏しかったナノ空間の流体挙動をその場観察する革新的な計測技術として、高い挑戦性と価値を有する。

Outline of Final Research Achievements

Fluid dynamics in nanometer-scale space is significantly deviated from that in macroscale bulk liquid because the strong viscousity arises from the walls and the approximation of the Debye length no longer holds. A bottleneck of the experimental study on this nanoscale fluidics is the lack of techniques that can analyze the nanoscale flow in situ. In this study, fluorescent nanodiamond particles were introduced into the polymer nanostructure (nanopores) as probes to simultaneously observe changes in the rotation and translational Brownian motion of the nanoparticles. We clarified how spin signals of the fluorescent nanodiamond particles respond to changes in pH and excitation light intensity. We have also succeeded in introducing nanoparticles inside polymer nanopores during the research term.

Academic Significance and Societal Importance of the Research Achievements

本研究は、ナノスケールの流体力学研究、および、それが密接に関連する生体微小構造などでの流体挙動に関する研究に新しい分析手法を提供しようとする試みである。この技術が実現できれば、現在中心的に利用される電気泳動などによるバルクスケールの観察や電子顕微鏡による静的な構造観察に加えて、光学顕微鏡という汎用性の高いシステムにおいて、その場ダイナミクス測定が可能となると期待される。これにより、流体力学のより深い理解が得られるだけでなく、蛋白質における分子輸送への応用など将来的には創薬や触媒開発研究を下支えする分析技術となることも期待される。

Report

(4 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (70 results)

All 2022 2021 2020 2019 Other

All Int'l Joint Research (2 results) Journal Article (18 results) (of which Int'l Joint Research: 5 results,  Peer Reviewed: 18 results,  Open Access: 12 results) Presentation (42 results) (of which Int'l Joint Research: 16 results,  Invited: 6 results) Book (1 results) Remarks (6 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Int'l Joint Research] ベルリン・フンボルト大学(ドイツ)

    • Related Report
      2020 Research-status Report
  • [Int'l Joint Research] 蘇州大学(中国)

    • Related Report
      2020 Research-status Report
  • [Journal Article] Probing the role of charged functional groups on nanoparticles grafted with polyglycerol in protein adsorption and cellular uptake2022

    • Author(s)
      Yajuan Zou,Shinji Ito,Masazumi Fujiwara,Naoki Komatsu
    • Journal Title

      Advanced Functional Materials

      Volume: na Issue: 22 Pages: 2111077-2111077

    • DOI

      10.1002/adfm.202111077

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Fabrication of Metal-Insulator-Metal Nanostructures Composed of Au-MgF2-Au and Its Potential in Responding to Two Different Factors in Sample Solutions Using Individual Plasmon Modes2022

    • Author(s)
      Yamada Hirotaka、Kawasaki Daiki、Sueyoshi Kenji、Hisamoto Hideaki、Endo Tatsuro
    • Journal Title

      Micromachines

      Volume: 13 Issue: 2 Pages: 257-257

    • DOI

      10.3390/mi13020257

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Au nanorods-TiO2 photonic crystal plasmonic-photonic hybrid sensor for label-free detection and identification of DNA molecules with single nucleotide polymorphisms2022

    • Author(s)
      Kawasaki Daiki、Yamada Hirotaka、Sueyoshi Kenji、Hisamoto Hideaki、Endo Tatsuro
    • Journal Title

      Sensors and Actuators B: Chemical

      Volume: 361 Pages: 131747-131747

    • DOI

      10.1016/j.snb.2022.131747

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Diamond quantum thermometry: From foundations to applications2021

    • Author(s)
      Masazumi Fujiwara and Yutaka Shikano
    • Journal Title

      Nanotechnology

      Volume: 32 Issue: 48 Pages: 482002-482002

    • DOI

      10.1088/1361-6528/ac1fb1

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Modulating Optical Characteristics of Nanoimprinted Plasmonic Device by Re-Shaping Process of Polymer Mold2021

    • Author(s)
      Yamada Hirotaka、Sueyoshi Kenji、Hisamoto Hideaki、Endo Tatsuro
    • Journal Title

      Micromachines

      Volume: 12 Issue: 11 Pages: 1323-1323

    • DOI

      10.3390/mi12111323

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Wide-field fluorescent nanodiamond spin measurements toward real-time large-area intracellular thermometry2021

    • Author(s)
      Yushi Nishimura, Keisuke Oshimi, Yumi Umehara, Yuka Kumon, Kazu Miyaji, Hiroshi Yukawa, Yutaka Shikano, Tsutomu Matsubara, Masazumi Fujiwara, Yoshinobu Baba, Yoshio Teki
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 4248-4248

    • DOI

      10.1038/s41598-021-83285-y

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Operando time-resolved diffuse reflection spectroscopy: the origins of photocatalytic water-oxidation activity of bismuth vanadate2020

    • Author(s)
      Miyasato Ryo、Fujiwara Masazumi、Uragami Chiasa、Sato Haruyuki、Yano Toshihiro、Hashimoto Hideki
    • Journal Title

      Journal of Photochemistry and Photobiology A: Chemistry

      Volume: - Pages: 112493-112493

    • DOI

      10.1016/j.jphotochem.2020.112493

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A quantum thermometric sensing and analysis system using fluorescent nanodiamonds for the evaluation of living stem cell functions according to intracellular temperature2020

    • Author(s)
      Hiroshi Yukawa, Masazumi Fujiwara, Kaori Kobayashi, Yuka Kumon, Kazu Miyaji, Yushi Nishimura, Keisuke Oshimi, Yumi Umehara, Yoshio Teki, Takayuki Iwasaki, Mutsuko Hatano, Hideki Hashimoto and Yoshinobu Baba
    • Journal Title

      Nanoscale Advances

      Volume: 2 Issue: 5 Pages: 1859-1868

    • DOI

      10.1039/d0na00146e

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Photoprotective mechanisms in the core LH1 antenna pigment-protein complex from the purple photosynthetic bacterium, Rhodospirillum rubrum2020

    • Author(s)
      Chiasa Uragami, Hiroki Sato, NaoYukihira, MasazumiFujiwara, Daisuke Kosumi, Alastair T.Gardiner, Richard J.Cogdell, Hideki Hashimoto
    • Journal Title

      Journal of Photochemistry and Photobiology A: Chemistry

      Volume: 400 Pages: 112628-112628

    • DOI

      10.1016/j.jphotochem.2020.112628

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Real-time nanodiamond thermometry probing in vivo thermogenic responses2020

    • Author(s)
      Masazumi Fujiwara, Simo Sun, Alexander Dohms, Yushi Nishimura, Ken Suto, Yuka Takezawa, Keisuke Oshimi, Li Zhao, Nikola Sadzak, Yumi Umehara, Yoshio Teki, Naoki Komatsu, Oliver Benson, Yutaka Shikano, Eriko Kage-Nakadai
    • Journal Title

      Science Advances

      Volume: 6 Issue: 37 Pages: eaba9636

    • DOI

      10.1126/sciadv.aba9636

    • NAID

      120006886567

    • URL

      https://ocu-omu.repo.nii.ac.jp/records/2020469

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Real-time estimation of the optically detected magnetic resonance shift in diamond quantum thermometry toward biological applications2020

    • Author(s)
      Masazumi Fujiwara, Alexander Dohms, Ken Suto, Yushi Nishimura, Keisuke Oshimi, Yoshio Teki, Kai Cai, Oliver Benson, and Yutaka Shikano
    • Journal Title

      Phys. Rev. Research

      Volume: 2 Issue: 4 Pages: 043415-043415

    • DOI

      10.1103/physrevresearch.2.043415

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Template Stripping Method-Based Au Nanoarray for Surface-Enhanced Raman Scattering Detection of Antiepileptic Drug2020

    • Author(s)
      Tatsuro Endo, Hirotaka Yamada, Kenji Yamada
    • Journal Title

      Mivromachines

      Volume: 11 Issue: 10 Pages: 936-936

    • DOI

      10.3390/mi11100936

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Au "Edged Hole Array" for Sensor Application2019

    • Author(s)
      Hirotaka Yamada, Daiki Kawasaki, Chigusa Inoue, Kenichi Maeno, Kenji Sueyoshi, Hideaki Hisamoto, Tatsuro Endo
    • Journal Title

      Journal of Photopolymer Science and Technology

      Volume: 32 Issue: 1 Pages: 101-105

    • DOI

      10.2494/photopolymer.32.101

    • NAID

      130007744377

    • ISSN
      0914-9244, 1349-6336
    • Year and Date
      2019-06-24
    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Particle size effects of tetrahedron-shaped Ag3PO4 photocatalyst on water-oxidation activity and carrier recombination dynamics2019

    • Author(s)
      Miyasato Ryo、Fujiwara Masazumi、Sato Haruyuki、Yano Toshihiro、Hashimoto Hideki
    • Journal Title

      Chemical Physics Letters: X

      Volume: 2 Pages: 100023-100023

    • DOI

      10.1016/j.cpletx.2019.100023

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Monitoring spin coherence of single nitrogen-vacancy centers in nanodiamonds during pH changes in aqueous buffer solutions2019

    • Author(s)
      Masazumi Fujiwara, Ryuta Tsukahara, Yoshihiko Sera, Hiroshi Yukawa, Yoshinobu Baba, Shinichi Shikata, and Hideki Hashimoto
    • Journal Title

      RSC Advances

      Volume: 9 Issue: 22 Pages: 12606-12614

    • DOI

      10.1039/c9ra02282a

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Removing Non-Size-Dependent Electron Spin Decoherence of Nanodiamond Quantum Sensors by Aerobic Oxidation2019

    • Author(s)
      Ryuta Tsukahara, Masazumi Fujiwara, Yoshihiko Sera, Yushi Nishimura, Yuko Sugai, Christian Jentgens, Yoshio Teki, Hideki Hashimoto and Shinichi Shikata
    • Journal Title

      ACS Applied Nano Materials

      Volume: 2 Issue: 6 Pages: 3701-3710

    • DOI

      10.1021/acsanm.9b00614

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Core?Shell-Structured Gold Nanocone Array for Label-Free DNA Sensing2019

    • Author(s)
      Daiki Kawasaki, Hirotaka Yamada, Kenichi Maeno, Kenji Sueyoshi, Hideaki Hisamoto, Tatsuro Endo
    • Journal Title

      ACS Appl. Nano Mater.

      Volume: 2 Issue: 8 Pages: 4983-4990

    • DOI

      10.1021/acsanm.9b00930

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] TiN-contained polymer-metal core-shell structured nanocone array: Engineering of sensor performance by controlling plasmonic properties2019

    • Author(s)
      Daiki Kawasaki, Kenichi Maeno, Hirotaka Yamada, Kenji Sueyoshi, Hideaki Hisamoto, Tatsuro Endo
    • Journal Title

      Sensors and Actuators B: Chemical

      Volume: 299 Pages: 126932-126932

    • DOI

      10.1016/j.snb.2019.126932

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Presentation] プラズモニック結晶を用いた非標識PCR法の開発2022

    • Author(s)
      古川ふう大,山田大空,川崎大輝,西辻凌輔,遠藤達郎,末吉健志,久本秀明
    • Organizer
      第69回応用物理学会春季学術講演会
    • Related Report
      2021 Annual Research Report
  • [Presentation] Real-time nanodiamond thermometry probing nematode worms2021

    • Author(s)
      Masazumi Fujiwara, Simo Sun, Alexander Dohms, Yushi Nishimura, Ken Suto, Yuka Takezawa, Keisuke Oshimi, Li Zhao, Nikola Sadzak, Yumi Umehara, Yoshio Teki, Naoki Komatsu, Oliver Benson, Yutaka Shikano, and Eriko Kage-Nakadai
    • Organizer
      International Conference on New Diamond and Nano Carbons
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Antenna-integrated culture dishes for 10-mm-scale large-area detection of optically detected magnetic resonance of nanodiamond NV centers2021

    • Author(s)
      Keisuke Oshimi, Yushi Nishimura, Eiji Shikoh, Yuka Takezawa, Eriko Kage-Nakadai, Masazumi Fujiwara, Yoshio Teki
    • Organizer
      14th International Conference on New Diamond and Nano Carbons 2020/2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Antenna-integrated culture dishes for large-area detection of optically detected magnetic resonance of nanodiamond NV centers2021

    • Author(s)
      Keisuke Oshimi, Yushi Nishimura, Eiji Shikoh, Yuka Takezawa, Eriko Kage-Nakadai, Masazumi Fujiwara, Yoshio Teki
    • Organizer
      ISMAR-APNMR 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ダイヤモンド量子センサを用いた温度計測に関する考察2021

    • Author(s)
      藤原正澄
    • Organizer
      量子生命科学会第3回大会
    • Related Report
      2021 Annual Research Report
  • [Presentation] ダイヤモンド量子センシング温度計を用いたナノ温度計測2021

    • Author(s)
      藤原正澄
    • Organizer
      2021 年日本化学会中国四国支部大会 高知大会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 蛍光ナノダイヤモンド量子センサの温度計測と生体計測応用2021

    • Author(s)
      藤原正澄
    • Organizer
      Biothermology Workshop 2021
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 蛍光ナノダイヤモンドの光スピン計測と生体分析への応用2021

    • Author(s)
      藤原正澄
    • Organizer
      光応用光学特別研究会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] フォトニック結晶を用いたDNAメチル化の光検出2021

    • Author(s)
      中島悠佑,小林奈緒,植田渉太郎,川崎大輝,末吉健志,久本秀明,遠藤達郎
    • Organizer
      化学とマイクロ・ナノシステム学会 第43回研究会
    • Related Report
      2021 Annual Research Report
  • [Presentation] イオン選択性可塑化PVC複合型プラズモニックイオンセンサの開発2021

    • Author(s)
      遠藤達郎,井上千種,川崎大輝,山田大空,末吉健志,久本秀明
    • Organizer
      第38回「センサ・マイクロマシンと応用システム」シンポジウム
    • Related Report
      2021 Annual Research Report
  • [Presentation] バイオセンシング応用を指向したプラズモニックデバイスの開発2021

    • Author(s)
      遠藤達郎
    • Organizer
      第20回プラズモニック化学シンポジウム
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Real-time nanodiamond thermometry probing in vivo thermogenic responses2021

    • Author(s)
      Masazumi Fujiwara, Simo Sun, Alexander Dohms, Yushi Nishimura, Ken Suto, Yuka Takezawa, Keisuke Oshimi, Li Zhao, Nikola Sadzak, Yumi Umehara, Yoshio Teki, Naoki Komatsu, Oliver Benson, Yutaka Shikano, and Eriko Kage-Nakadai
    • Organizer
      SPIE Photonics West 2021
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research
  • [Presentation] ダイヤモンドN V 中心の 電子 スピン 共鳴周波数が示す光強度 依存性とセンシングにおける アーティファクト2021

    • Author(s)
      藤原正澄, A. Doh ms, 首藤 健, 西村 勇 姿, 押味 佳裕, 手木芳男, 蔡 凱, O. Benson, 鹿野 豊
    • Organizer
      日本物理学会第76回年次大会(2021年)
    • Related Report
      2020 Research-status Report
  • [Presentation] 広領域でナノダイヤモンドのNV 中心の光検出磁気共鳴が可能なアンテナ一体型ディッシュの開発2021

    • Author(s)
      押味 佳裕, 西村 勇姿,仕幸 英治,竹澤 有華,中台 枝里子,藤原 正澄,手木 芳男
    • Organizer
      第68回春季応用物理学会春季学術講演会
    • Related Report
      2020 Research-status Report
  • [Presentation] Nanodiamond quantum sensing and its application to biological thermometry2020

    • Author(s)
      Masazumi Fujiwara
    • Organizer
      2020 MRS Virtual Spring/Fall Meeting & Exhibit
    • Related Report
      2020 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 電子スピン共鳴融合型蛍光顕微鏡による線虫のin-vivo温度計測2020

    • Author(s)
      藤原正澄,S. Sun,A. Dohms,西村勇姿,首藤健,竹澤有華,押味佳裕,L. Zhao, N. Sadzak, 梅原有美,手木芳男,小松直樹,O. Benson,鹿野豊,中台(鹿毛)枝里子
    • Organizer
      日本顕微鏡学会第76回学術講演会
    • Related Report
      2020 Research-status Report
  • [Presentation] 生体内リアルタイム蛍光ナノダイヤモンド温度計測2020

    • Author(s)
      藤原正澄, Simo Sun, Alexander Dohms, 西村勇姿, 首藤 健, 竹澤有華, 押見佳裕, Li Zhao, Nikola Sadzak, 梅原有美, 手木芳男, 小松直樹, Oliver Benson, 鹿野 豊, 中台枝里子
    • Organizer
      量子情報技術研究会(QIT)
    • Related Report
      2020 Research-status Report
  • [Presentation] 生体内リアルタイム蛍光ナノダイヤモンド温度計測2020

    • Author(s)
      藤原 正澄, Sun S, Dohms A, 西村 勇姿, 首藤 健, 竹澤 有華, 押味 佳裕, Zhao L, Sadzak N, 梅原 有美, 手木 芳男, 小松 直樹, Benson O, 鹿野 豊, 中台 枝里子
    • Organizer
      第81回応用物理学会秋季学術講演会
    • Related Report
      2020 Research-status Report
  • [Presentation] 蛍光ナノダイヤモンドによる温度計測2020

    • Author(s)
      藤原 正澄
    • Organizer
      量子生命科学会第2回大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 広領域マイクロ波照射が可能な細胞培養ディッシュの開発2020

    • Author(s)
      押味 佳裕、西村 勇姿、田中 益明、仕幸 英治、松原 勤、藤原 正澄、手木 芳男
    • Organizer
      量子生命科学会第2回大会
    • Related Report
      2020 Research-status Report
  • [Presentation] Surface oxidation and electron-spin coherence of nitrogen-vacancy centres in nanodiamonds2019

    • Author(s)
      Masazumi Fujiwara, Ryuta Tsukahara, Yoshihiko Sera, Yushi Nishimura, Yuko Sugai, Christian Jentgens, Yoshio Teki, Hideki Hashimoto, Shinichi Shikata
    • Organizer
      13th New Diamond and Nano Carbon Conference (NDNC 2019)
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Quantum thermometry of nanodiamonds for characterizing stem-cell differentiation2019

    • Author(s)
      M.Fujiwara, K. Kobayashi, Y. Kumon, K. Miyaji, H. Yukawa, Y. Baba, T. Iwasaki, M. Hatano, H. Hashimoto
    • Organizer
      Gordon Research Conference: Quantum Sensing Applications in Metrology and Imaging
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Nanodiamond quantum thermometry for biological applications2019

    • Author(s)
      Masazumi Fujiwara
    • Organizer
      International Workshop on Quantum Sensing & Biophotonics 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Influence of the surface oxidation to the spin coherence of properties of single NV centers in nanodiamonds2019

    • Author(s)
      Ryuta Tsukahara, Masazumi Fujiwara, Yoshihiko Sera, Hideki Hashimoto, Shinichi Shikata
    • Organizer
      International Workshop on Quantum Sensing & Biophotonics 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Spatial correlation between NV centers and nonfluorescent defects in N-doped bulk diamond2019

    • Author(s)
      Hiroki Kuromatsu, Ryuta Tsukahara, Tokuyuki Teraji, Masazumi Fujiwara, Shinichi Shikata
    • Organizer
      International Workshop on Quantum Sensing & Biophotonics 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Realtime nanodiamond thermometry probing in-vivo thermogenic responses2019

    • Author(s)
      M. Fujiwara, S. Sun, A. Dohms, Y. Nishimura, K. Suto, Y. Takezawa, K. Oshimi, L. Zhao, N. Sadzak, Y. Umehara, Y. Teki, N. Komatsu, O. Benson, Y. Shikano, E. Kage-Nakadai
    • Organizer
      International Workshop on Quantum Sensing & Biophotonics 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Construction of wide-field optically detected magnetic resonance method for intracellular temperature imaging2019

    • Author(s)
      Yushi Nishimura, Yuka Kumon, Kazu Miyaji, Tsutomu Matsubara, Kazuo Ikeda, Hiroshi Yukawa, Yoshinobu Baba, Yoshio Teki, Masazumi Fujiwara
    • Organizer
      International Workshop on Quantum Sensing & Biophotonics 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Microwave-antenna-integrated cell dishes for nanodiamond quantum thermometry2019

    • Author(s)
      K. Oshimi, Y. Nishimura, T. Matsubara, M. Tanaka, E. Shikoh, M. Fujiwara, Y. Teki
    • Organizer
      International Workshop on Quantum Sensing & Biophotonics 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Temperature sensing of stem cell regenerative function with fluorescent nanodiamond2019

    • Author(s)
      Kazu Miyaji, Hiroshi Yukawa, Masazumi Fujiwara, Yushi Nishimura, Daisuke Onoshima,Yoshinobu Baba
    • Organizer
      International Workshop on Quantum Sensing & Biophotonics 2019
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Fluorescent Nanodiamonds for Quantum Applications2019

    • Author(s)
      Masazumi Fujiwara
    • Organizer
      The 13th Japanese Russian Workshop on “Open Shell Compounds and Molecular Spin Devices”
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Construction of wide-field optically detected magnetic resonance method for intracellular temperature imaging2019

    • Author(s)
      Yushi Nishimura, Yuka Kumon, Kazu Miyaji, Tsutomu Matsubara, Kazuo Ikeda, Hiroshi Yukawa, Yoshinobu Baba, Yoshio Teki, Masazumi Fujiwara
    • Organizer
      3 rd QST International Symposium “Quantum Life Science
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] ナノダイヤモンド量子温度センシングとその汎用計測システムの開発2019

    • Author(s)
      藤原 正澄, 湯川 博, 小林 香央里, 梅原 有美, 公文 優花, 宮地 冬, 岩崎 孝之, 波多野 睦子, 橋本 秀樹, 馬場 嘉信
    • Organizer
      量子生命科学会第1回大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 蛍光ナノダイヤモンドを用いたリアルタイム温度計測2019

    • Author(s)
      藤原 正澄, Dohms Alexander, 西村 勇姿, 手木 芳男, Benson Oliver, 鹿野 豊
    • Organizer
      第80回応用物理学会秋季学術講演会
    • Related Report
      2019 Research-status Report
  • [Presentation] 広い空間領域で光検出磁気共鳴が検出可能なアンテナ集積化培養ディッシュの開発2019

    • Author(s)
      押味 佳裕, 西村 勇姿, 田中 益明, 仕幸 英治, 藤原 正澄, 手木 芳男
    • Organizer
      第80回応用物理学会秋季学術講演会
    • Related Report
      2019 Research-status Report
  • [Presentation] 量子ドットによる細胞内温度計測2019

    • Author(s)
      西村 勇姿, 宮地 冬, 公文 優花, 湯川 博, 馬場 嘉信, 藤原 正澄, 手木 芳男
    • Organizer
      第80回応用物理学会秋季学術講演会
    • Related Report
      2019 Research-status Report
  • [Presentation] Microwave-antenna-integrated cell dishes for nanodiamond quantum thermometry2019

    • Author(s)
      Keisuke Oshimi, Yushi Nishimura, Masuaki Tanaka, Eiji Shikoh, Masazumi Fujiwara, Yoshio Teki
    • Organizer
      第28回日本バイオイメージング学会学術集会/第6回国際バイオイメージングシンポジウム
    • Related Report
      2019 Research-status Report
  • [Presentation] 細胞内温度イメージングに向けたワイドフィールド光検出電子スピン共鳴測定法の構築2019

    • Author(s)
      西村勇姿, 公文優花, 宮地 冬, 松原 勤, 湯川 博, 馬場嘉信, 藤原正澄, 手木芳男
    • Organizer
      OCU先端光科学シンポジウム ―ナノフォトニクスが切り拓く分子運動・化学反応制御の探求―
    • Related Report
      2019 Research-status Report
  • [Presentation] Microwave-antenna-integrated cell dishes for nanodiamond quantum thermometry2019

    • Author(s)
      押味佳裕, 西村勇姿, 田中益明, 仕幸英治, 藤原正澄, 手木芳男
    • Organizer
      OCU先端光科学シンポジウム ―ナノフォトニクスが切り拓く分子運動・化学反応制御の探求―
    • Related Report
      2019 Research-status Report
  • [Presentation] 光・スピン量子計測が可能とする生体熱計測2019

    • Author(s)
      藤原正澄
    • Organizer
      LAC-SYS研究所 第2回シンポジウム
    • Related Report
      2019 Research-status Report
  • [Presentation] モールド形状制御によるナノインプリント製プラズモニック結晶のセンサ性能制御2019

    • Author(s)
      山田大空,志水友哉,小林奈緒,末吉健志,久本秀明,遠藤達郎
    • Organizer
      日本分析化学会第68年会
    • Related Report
      2019 Research-status Report
  • [Presentation] 広域プラズモン増強電場発生を示すMetal-Insulator-Metalドットアレイの開発2019

    • Author(s)
      山田大空,川﨑大輝,井上千種,前野権一,末吉健志,久本秀明,遠藤達郎
    • Organizer
      第80回応用物理学会秋季学術講演会
    • Related Report
      2019 Research-status Report
  • [Presentation] ポリマー製フォトニック結晶ナノ共振器の設計・作製と高感度光センサへの応用2019

    • Author(s)
      遠藤 達郎, 孫 佳儀, 前野 権一, 安藝 翔馬, 末吉 健志, 久本 秀明
    • Organizer
      第36回「センサ・マイクロマシンと応用システム」シンポジウム
    • Related Report
      2019 Research-status Report
  • [Book] 量子センシングハンドブック ~量子科学が切り拓く新たな領域~2021

    • Author(s)
      藤原正澄,中台枝里子,湯川博,馬場嘉信
    • Total Pages
      6
    • Publisher
      エヌ・ティー・エス
    • Related Report
      2020 Research-status Report
  • [Remarks] 代表者研究室ホームページ

    • URL

      https://www.nanochem-okayama-u.net/

    • Related Report
      2021 Annual Research Report
  • [Remarks] 分担者研究室ホームページ

    • URL

      http://www2.chem.osakafu-u.ac.jp/ohka/ohka1/

    • Related Report
      2021 Annual Research Report
  • [Remarks] 個人ホームページ

    • URL

      https://www.masazumifujiwara.net/

    • Related Report
      2020 Research-status Report
  • [Remarks] 代表者所属研究室ホームページ

    • URL

      http://www.sci.osaka-cu.ac.jp/chem/RKINOU/

    • Related Report
      2019 Research-status Report
  • [Remarks] 代表者個人ホームページ

    • URL

      https://www.masazumifujiwara.net/

    • Related Report
      2019 Research-status Report
  • [Remarks] 分担者ホームページ

    • URL

      http://www2.chem.osakafu-u.ac.jp/ohka/ohka1/ENDO/Ja/index.html

    • Related Report
      2019 Research-status Report
  • [Patent(Industrial Property Rights)] ODMR温度測定方法2020

    • Inventor(s)
      藤原正澄
    • Industrial Property Rights Holder
      藤原正澄
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Related Report
      2020 Research-status Report
    • Overseas

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Published: 2019-07-04   Modified: 2023-01-30  

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