| Project/Area Number |
19K23436
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Multi-year Fund |
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| Review Section |
0203:Particle-, nuclear-, astro-physics, and related fields
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| Research Institution | The University of Tokyo |
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Principal Investigator |
Caradonna Pietro 東京大学, カブリ数物連携宇宙研究機構, 特任研究員 (10846520)
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| Project Period (FY) |
2019-08-30 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | Entanglement / Compton scattering / medical imaging / Compton Cameras / entangled photons / Compton PET / Compton camera / PET imaging |
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| Outline of Research at the Start |
The aim is to have a level of sensitivity in PET to increase the sensitivity to detect the onset of metastatic cancer using only the signal of back-to-back 511 keV gammas. Our aim is to increase the detection sensitivity by correcting the trajectory of the photon that has Compton scattered inside the patient. In principle, the scattering site can still be found even when one of the photons Compton scatters inside the patient. Plotting all possible sites can provide a novel method of generating 3D anatomical maps.
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| Outline of Final Research Achievements |
We apply quantum entanglement to correct for scattering loses in Positron Emission Tomography (PET). We have reformulated Compton scattering of entangled photons in terms Stoke’s matrices, making it easier to understand the underlying scattering dynamics, and we found structures in the cross-section which are solely due to entanglement.
We found a particular Compton scattering configuration to find the scattering sites, which we call “the touch cone configuration”. This idea is under a provisional patent and will be applied in future work. We have also included atomic electron binding effects as well, which will make future GEANT4 simulations reflect more accurately the scattering processes in biological material.
The significance of locating scattering sites paves the way for the development of a single modality machine which combines the analytical reach of a PET and CT scanner resulting in reduced radiation exposure to the patient, as well as correcting for attenuation.
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| Academic Significance and Societal Importance of the Research Achievements |
The scientific of the success of this research would pave the way for the development of a single modality machine which combines the analytical reach of a combined PET and CT scanner into one system resulting in reduced radiation exposure to the patient, as well as correcting for attenuation.
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