• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Experimental validation of sleep regulatory factors involved in the diurnal variation of sleep bruxism

Research Project

Project/Area Number 19K24069
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeMulti-year Fund
Review Section 0907:Oral science and related fields
Research InstitutionOsaka University

Principal Investigator

haraki shingo  大阪大学, 歯学研究科, 招へい教員 (70845982)

Project Period (FY) 2019-08-30 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords睡眠時ブラキシズム / ポリソムノグラフィー / 睡眠 / ポリソムノグラフィ
Outline of Research at the Start

ポリソムノグラフィ(Polysomnography:PSG)検査により睡眠時データを採取する.それによって睡眠時ブラキシズム(Sleep Bruxism:SB)の確定診断が下った被験者に対して,3夜連続の睡眠妨害の介入を伴うPSG検査を行い,SBに関連する咬筋活動の変化と睡眠構築の変化との関連性の比較を行う.睡眠検査とそのデータ解析や睡眠障害の診断には専門知識・技術が必要なため,睡眠医療の専門家とのチーム体制で研究を遂行する.

Outline of Final Research Achievements

In this study, polysomnography (PSG) testing was performed on two consecutive nights in a sleep laboratory in young healthy adults. The severity of sleep bruxism (SB) was then diagnosed, and the influence of diurnal variation on the SB diagnosis was examined. Subsequently, in the severe SB group, we examined the relationship between variability of masticatory muscle activity and sleep. The results showed that rhythmic masticatory muscle activity (RMMA), a diagnostic marker of SB, decreased on the first night of PSG testing due to the first night effect, and that the diurnal variability of RMMA was greater in the severe SB group. In addition, the variability was influenced by the changes of arousal occurrence related to ultradian rhythms, rather than the increase of arousal-related variables.

Academic Significance and Societal Importance of the Research Achievements

歯科の臨床現場ではすでに様々な治療方法が提案されているが、睡眠時ブラキシズムの診断方法は確立されておらず、病態生理は不明である。本研究では、第一夜効果による睡眠の質の低下がRMMAの発生を誘発するものでないことを明らかにした点が学術的に意義がある。また睡眠時ブラキシズムの日間変動の動態に関する生理学的機序を明らかにすることは、睡眠時ブラキシズムの診断や治療の評価において、科学的アプローチを明確にする一助となったと考えている。

Report

(4 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (6 results)

All 2021 2020 2019

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 2 results) Presentation (2 results)

  • [Journal Article] A lack of specific motor patterns between rhythmic/non-rhythmic masticatory muscle activity and bodily movements in sleep bruxism2021

    • Author(s)
      Imai Hideto、Haraki Shingo、Tsujisaka Akiko、Okura Mutsumi、Adachi Hiroyoshi、Ohno Yuko、Yatani Hirofumi、Kato Takafumi
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 65 Issue: 3 Pages: 415-420

    • DOI

      10.2186/jpr.JPR_D_20_00012

    • NAID

      130008076970

    • ISSN
      1883-1958, 1883-9207
    • Related Report
      2021 Annual Research Report 2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] First night effect on polysomnographic sleep bruxism diagnosis varies among young subjects with different degrees of rhythmic masticatory muscle activity2020

    • Author(s)
      Haraki Shingo、Tsujisaka Akiko、Toyota Risa、Shiraishi Yuki、Adachi Hiroyoshi、Ishigaki Shoichi、Yatani Hirofumi、Taniike Masako、Kato Takafumi
    • Journal Title

      Sleep Medicine

      Volume: 75 Pages: 395-400

    • DOI

      10.1016/j.sleep.2020.08.012

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Polysomnographic Analysis of Respiratory Events During Sleep in Young Non-Obese Japanese Adults Without Clinical Complaints of Sleep Apnea.2020

    • Author(s)
      Okura M, Nonoue S, Tsujisaka A, Haraki S, Yokoe C, Taniike M, Kato T.
    • Journal Title

      Clin Sleep Med

      Volume: - Issue: 8 Pages: 1303-1310

    • DOI

      10.5664/jcsm.8498

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Sleep stage dynamics in young patients with sleep bruxism2020

    • Author(s)
      Kishi Akifumi、Haraki Shingo、Toyota Risa、Shiraishi Yuki、Kamimura Mayo、Taniike Masako、Yatani Hirofumi、Kato Takafumi
    • Journal Title

      Sleep

      Volume: 43 Issue: 1 Pages: 1-12

    • DOI

      10.1093/sleep/zsz202

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 睡眠時ブラキシズム患者の第一夜効果における睡眠構築と自律神経活動の役割2020

    • Author(s)
      原木真吾、辻坂亮子、豊田理紗、石垣尚一、瑞森崇弘、矢谷博文、加藤隆史
    • Organizer
      第129回日本補綴歯科学会学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 2夜連続のポリソムノグラフィ検査における睡眠時ブラキシズムの重症度診断の比較2019

    • Author(s)
      原木真吾,辻坂亮子,豊田理紗,石垣尚一,瑞森崇弘,矢谷博文,加藤隆史
    • Organizer
      第128回日本補綴歯科学会学術大会
    • Related Report
      2019 Research-status Report

URL: 

Published: 2019-09-03   Modified: 2023-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi