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Exploration of swallowing function and food properties affecting pharyngeal residues -Evaluation of pharyngeal residues by retronasal aroma-

Research Project

Project/Area Number 19K24115
Research Category

Grant-in-Aid for Research Activity Start-up

Allocation TypeMulti-year Fund
Review Section 0907:Oral science and related fields
Research InstitutionNiigata University

Principal Investigator

Okawa Jumpei  新潟大学, 医歯学系, 助教 (10846041)

Project Period (FY) 2019-08-30 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords咽頭残留 / 嚥下機能 / レトロネーザル / ニオイセンサ / 咀嚼機能 / 嚥下障害 / 食品物性
Outline of Research at the Start

超高齢社会を迎えた日本では、肺炎は死因の第3位を占め、その多くは誤嚥性肺炎である。しかし、誤嚥の原因となる咽頭残留を簡便かつ定量的に評価する方法は確立されていない。申請者は、食品から放出された香気が咽頭から鼻腔へと流れる経路(レトロネーザル)に着目し、香気量から咽頭残留を短時間で定量評価できる可能性を見出してきた。本研究課題では、咽頭残留の定量評価法の確立を目指すとともに、さらに嚥下障害患者における咽頭残留の影響因子について検討することを目的とする。

Outline of Final Research Achievements

Residual food in the pharynx (pharyngeal residue) causes aspiration pneumonia, however no method has been established to assess its residual amount. The aroma released from food during eating is transported to the nasal cavity via the pharynx. We hypothesized that the amount of the pharyngeal residue can be evaluated by measuring the aroma intensity from the nostrils.
Essence was dispensed into the pharynx of healthy adults and the aroma intensity using an odor sensor from the nostril. As a result, the aroma intensity increased as the amount of the essence in the pharynx increased. In addition, by calculating the approximate curve to estimate the aroma intensity, the amount of the pharyngeal residue could be predicted in a short time. Furthermore, the thickened water used for dysphagia patients releases the aroma stably. It is suggested that the amount of the pharyngeal residual can be evaluated in the dysphagia patient.

Academic Significance and Societal Importance of the Research Achievements

超高齢社会を迎えた日本では、肺炎は死因の第3位を占め、その多くは誤嚥性肺炎である。しかし、誤嚥の原因となる食品の咽頭への残留を簡便かつ定量的に評価する方法は確立されておらず、多くは嚥下造影や嚥下内視鏡による定性的な評価にとどまっている。そこで、食品から放出された香りが咽頭から鼻腔へと流れる経路(レトロネーザル)に着目し、香りの強さを測定することで咽頭残留の量を測定する研究を行っている。本研究から、咽頭残留の簡便かつ定量的な評価が可能となれば、食品物性や嚥下機能と関連付けた咽頭残留の評価が可能となり、嚥下障害の病態解明やリハビリテーションに貢献できるものと考えている。

Report

(4 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • Research Products

    (22 results)

All 2021 2020 2019

All Journal Article (9 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 9 results,  Open Access: 4 results) Presentation (13 results) (of which Int'l Joint Research: 4 results,  Invited: 1 results)

  • [Journal Article] Modulation of tongue motion and tongue pressure during liquid swallowing with different bolus volumes2021

    • Author(s)
      Kodama Shohei、Fujiwara Shigehiro、Okawa Jumpei、Shitara Satoko、Hori Kazuhiro、Ono Takahiro
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 48 Issue: 11 Pages: 1243-1251

    • DOI

      10.1111/joor.13248

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of hard gummy candy chewing on masticatory function2021

    • Author(s)
      Fujiwara Shigehiro、Hori Kazuhiro、Shitara Satoko、Okawa Jumpei、Kodama Shohei、Murakami Kazuhiro、Ono Takahiro
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 48 Issue: 8 Pages: 909-915

    • DOI

      10.1111/joor.13208

    • Related Report
      2021 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of fracture properties of gels on tongue pressure during different phases of squeezing and swallowing2021

    • Author(s)
      Murakami Kazuhiro、Tokuda Yoshitsugu、Hori Kazuhiro、Minagi Yoshitomo、Uehara Fumiko、Okawa Jumpei、Ishihara Sayaka、Nakauma Makoto、Funami Takahiro、Maeda Yoshinobu、Ikebe Kazunori、Ono Takahiro
    • Journal Title

      Journal of Texture Studies

      Volume: - Issue: 3 Pages: 1-2

    • DOI

      10.1111/jtxs.12593

    • Related Report
      2021 Annual Research Report 2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Higher Masticatory Performance and Higher Number of Chewing Strokes Increase Retronasal Aroma2021

    • Author(s)
      Okawa Jumpei、Hori Kazuhiro、Yoshimoto Tasuku、Salazar Simonne E.、Ono Takahiro
    • Journal Title

      Frontiers in Nutrition

      Volume: 8

    • DOI

      10.3389/fnut.2021.623507

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Reliability of a novel wearable device to measure chewing frequency2021

    • Author(s)
      Hori Kazuhiro、Uehara Fumiko、Yamaga Yoshio、Yoshimura Shogo、Okawa Jumpei、Tanimura Motoki、Ono Takahiro
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 65 Issue: 3 Pages: 340-345

    • DOI

      10.2186/jpr.JPR_D_20_00032

    • NAID

      130008076973

    • ISSN
      1883-1958, 1883-9207
    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Coordination between lingual motion and pressure production during dipper/tipper type swallows2020

    • Author(s)
      Shitara Satoko、Fujiwara Shigehiro、Okawa Jumpei、Kodama Shohei、Hori Kazuhiro、Ono Takahiro
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 47 Issue: 12 Pages: 1479-1488

    • DOI

      10.1111/joor.13079

    • Related Report
      2020 Research-status Report
    • Peer Reviewed
  • [Journal Article] Differentiation of Feeding Behaviors Based on Masseter and Supra-Hyoid Muscle Activity2020

    • Author(s)
      Uehara Fumiko、Hori Kazuhiro、Murakami Kazuhiro、Okawa Jumpei、Ono Takahiro
    • Journal Title

      Frontiers in Physiology

      Volume: 11 Pages: 618-618

    • DOI

      10.3389/fphys.2020.00618

    • Related Report
      2020 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Estimation of pharyngeal residue after swallowing by retronasal aroma2020

    • Author(s)
      Okawa Jumpei、Hori Kazuhiro、Fujiwara Shigehiro、Uehara Fumiko、Shitara Satoko、Kodama Shohei、Ono Takahiro
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 印刷中 Issue: 7 Pages: 880-888

    • DOI

      10.1111/joor.12974

    • Related Report
      2019 Research-status Report
    • Peer Reviewed
  • [Journal Article] Masticatory performance analysis using photographic image of gummy jelly2019

    • Author(s)
      Salazar Simonne、Hori Kazuhiro、Uehara Fumiko、Okawa Jumpei、Shibata Akihide、Higashimori Mitsuru、Nokubi Takashi、Ono Takahiro
    • Journal Title

      Journal of Prosthodontic Research

      Volume: 64 Issue: 1 Pages: 48-54

    • DOI

      10.1016/j.jpor.2019.04.010

    • NAID

      130007845543

    • ISSN
      1883-1958, 1883-9207
    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Your Urge to Swallow may be Influenced by Retronasal Aroma2021

    • Author(s)
      Jumpei Okawa, Kazuhiro Hori, Tasuku Yoshimoto, Takahiro Ono
    • Organizer
      6th International Conference on Food Oral Processing 2021
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Detection of Pharyngeal Residue after Swallowing using Odor Sensor2021

    • Author(s)
      Jumpei Okawa, Kazuhiro Hori, Fumiko Uehara, Shohei Kodama, Satoko Shitara, Takahiro Ono
    • Organizer
      World Dysphagia Summit 2020
    • Related Report
      2021 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 舌運動と舌圧との同時計測による嚥下動態の解析2021

    • Author(s)
      大川純平、堀一浩、設樂仁子、兒玉匠平、小野高裕
    • Organizer
      LIFE 2020-2021
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] 高い咀嚼能率はレトロネーザルアロマの発生を促進する2020

    • Author(s)
      大川純平,堀 一浩,善本 佑,小野高裕
    • Organizer
      令和2年度日本補綴歯科学会関越支部学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 異なる素材を用いて調製したとろみ液の飲み込み特性とレオロジー特性2020

    • Author(s)
      早川結樹,加藤麻奈,大川純平,堀 一浩,伊藤彩子,川上智美,宮地一裕,小野高裕
    • Organizer
      日本咀嚼学会第31回学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] 総合病院入院中の嚥下障害患者における咀嚼・嚥下機能と食事形態2020

    • Author(s)
      重本心平,堀 一浩,大川純平,宮島 久,小野高裕
    • Organizer
      日本咀嚼学会第31回学術大会
    • Related Report
      2020 Research-status Report
  • [Presentation] Masticatory performance analysis using photographic image of gummy jelly.2019

    • Author(s)
      Salazar S, Hori K, Uehara F, Okawa J, Shibata A, Higashimori M, Nokubi T, Ono T
    • Organizer
      97th General Session of International Association of Dental Research
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] Influence of masticatory performance and chewing stokes on retro-nasal aroma.2019

    • Author(s)
      Hori K, Okawa J, Salazar S, Ono T
    • Organizer
      31th Conference of the Society of Oral Physiology
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] 舌運動モーションキャプチャと舌圧測定を用いた舌癌切除患者の舌運動評価2019

    • Author(s)
      設樂仁子,藤原茂弘,堀一浩,兒玉匠平,大川純平,小野高裕
    • Organizer
      日本口腔リハビリテーション学会第33回学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 液体嚥下時舌圧と咽頭流入様相との関連2019

    • Author(s)
      大川純平, 堀 一浩, 小野高裕
    • Organizer
      日本口腔リハビリテーション学会第33回学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] とろみ水嚥下時の舌運動と舌圧発現様相との関係2019

    • Author(s)
      兒玉匠平,藤原茂弘,堀 一浩,設樂仁子,大川純平,小野高裕
    • Organizer
      第25回日本摂食嚥下リハビリテーション学会学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 咬筋・舌骨上筋群筋活動様相の違いから摂食様式を判別する新たな試み2019

    • Author(s)
      上原文子,堀 一浩,村上和裕,大川純平,小野高裕
    • Organizer
      令和元年度新潟歯学会第1回例会
    • Related Report
      2019 Research-status Report
  • [Presentation] Dipper嚥下時の舌運動と舌圧産生様相との関係2019

    • Author(s)
      兒玉匠平,藤原茂弘,設樂仁子,大川純平,堀 一浩,小野高裕
    • Organizer
      令和元年度新潟歯学会第1回例会
    • Related Report
      2019 Research-status Report

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Published: 2019-09-03   Modified: 2023-01-30  

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