| Project/Area Number |
19K24162
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Multi-year Fund |
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| Review Section |
0908:Society medicine, nursing, and related fields
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2019-08-30 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | dental caries status / fluoride varnish / fluoride mouth rinse / Myanmar schoolchildren / dental caries / caries risk tests / Fluoride Varnish / Fluoride Mouth Rinse / Myanmar school children / Myanmar / fluoride applications / school children |
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| Outline of Research at the Start |
A one-year intervention study will be conducted in Yangon city, Myanmar. From our results, we can provide useful information about comparative effects in inactivation of caries development between fluoride varnish and fluoride mouth rinse, and their anti-bacterial effects on cariogenic bacteria.
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| Outline of Final Research Achievements |
We investigated the anti-caries effects of school-based Fluoride Varnish (FV) application with 3-month interval and Fluoride Mouth Rinsing (FMR) weekly on primary teeth and evaluated the anti-microbial effects of FV or FMR on cariogenic bacteria among Myanmar children.
The application of FV over a 3-month interval was found to have a superior effect than weekly FMR. The data suggested that frequent FV application should be more utilized for high-risk children. Furthermore, this study revealed that caries experience and oral hygiene status was influenced by cariogenic bacteria. Therefore, it is important to diminish the amount of cariogenic bacteria and the degree of acid production from the perspective of caries prevention.
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| Academic Significance and Societal Importance of the Research Achievements |
From our results, we provided useful information about comparative effects in caries inactivation between FV application and FMR, and their anti-bacterial effects on cariogenic bacteria. Moreover, this study highlighted a better preventive strategy for school-based fluoride utilization in Myanmar.
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