Gestational hypertension and diabetes associated birth outcome, and constant postpartum non-communicable disease risks
Project/Area Number |
19K24191
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Research Category |
Grant-in-Aid for Research Activity Start-up
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Allocation Type | Multi-year Fund |
Review Section |
0908:Society medicine, nursing, and related fields
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Research Institution | Nagasaki University |
Principal Investigator |
FERDOUS Farzana 長崎大学, 熱帯医学・グローバルヘルス研究科, 客員研究員 (90848623)
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Project Period (FY) |
2019-08-30 – 2024-03-31
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Project Status |
Granted (Fiscal Year 2022)
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Budget Amount *help |
¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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Keywords | Pregnancy / Post-pregnancy / NCD / Hypertension / Diabetes Mellitus / Pregnant women / Postpregnancy / Gestational diabetes / Non-communicable disease / Diabetes / Slum |
Outline of Research at the Start |
Research reveals that people living with scarcity are not only at a greater risk for infectious diseases but also are at increased threat for NCDs including reproductive age women.Therefore,the information will be obtained from this study will lead to a better understanding of the requirements of appropriate interventions in a larger population that are needed to reduce pregnancy-induced NCDs burden and adverse birth outcome. It will have also value in the reduction of diabetes as well as cardiovascular disease incidence at later diseases trajectory and will create further research prospect.
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Outline of Annual Research Achievements |
The study aimed to identify non-communicable disease (NCD) risks among women from Pregnancy to postpartum in the resource-limited populations in Bangladesh. This study is part of an observational pregnancy cohort conducted in Bangladesh, over 1 consecutive year. 387 women were recruited within 24-36 weeks of pregnancy, and 364 women were followed over at 6 months post-pregnancy. Data on blood pressure, blood glucose and/or glycosylated hemoglobin, and hemoglobin level were collected during pregnancy and after 6 months of post-pregnancy. The pregnant women's mean (sd) age was 24.4 (5.0) years. Ninety-three percent of women gave live birth. Overall, 18.9% (n=71/376) of women at the base were at NCDs risk, but this risk was elevated at follow-up to 55.5% (n=196/353). At baseline, the incidence of pregnancy-induced hypertension (PIH) (SBP >140 mmHg & DBP >90 mmHg) was 8.8%, and elevated PIH (SBP >130-139 mmHg & DBP >80-89 mmHg) was 28.5%. At post-pregnancy follow-up, the incidence of elevated high blood pressure (HBP) was 12.8% and 3.05% had HBP. At baseline, the prevalence of gestational diabetes was 4.5% (HbA1c>6.4%) and glycemic intolerance (GI) 40.6% (HbA1C=5.4%-6.4%) using WHO criteria. At follow-up, the diabetic prevalence was 11% and GI was 46% (HbA1C=5.7%-6.4%). Five women died due to birth complications i.e. excessive bleeding or prolonged labor. The study findings advocate appropriate implementation programs for NCDs that linger from pregnancy in resource-limited contexts.
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Current Status of Research Progress |
Current Status of Research Progress
3: Progress in research has been slightly delayed.
Reason
Due to COVID-19 outbreaks and government declared locked-down, I had to on hold my ethical clearance process in Bangladesh as well as sometimes had to stop data collection for the outbreak. Finally I finished my data collection.
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Strategy for Future Research Activity |
The study abstract with the following title "Incidence of Diabetes and Hypertension among Postpartum Women in Bangladesh" has been submitted to the American Public Health Annual (APHA) 2023 Meeting & Expo. Principle Investigator will present these research findings if it's been accepted by APHA. This APHA meeting will be held in Atlanta, USA, Nov 12-15, 2023. Further, the manuscript will be submitted shortly to the Frontiers in Nutrition journal. All remaining funding will be expend only dissemination purpose.
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Report
(4 results)
Research Products
(1 results)