| Budget Amount *help |
¥403,650,000 (Direct Cost: ¥310,500,000、Indirect Cost: ¥93,150,000)
Fiscal Year 2012: ¥63,700,000 (Direct Cost: ¥49,000,000、Indirect Cost: ¥14,700,000)
Fiscal Year 2011: ¥63,700,000 (Direct Cost: ¥49,000,000、Indirect Cost: ¥14,700,000)
Fiscal Year 2010: ¥63,700,000 (Direct Cost: ¥49,000,000、Indirect Cost: ¥14,700,000)
Fiscal Year 2009: ¥105,170,000 (Direct Cost: ¥80,900,000、Indirect Cost: ¥24,270,000)
Fiscal Year 2008: ¥107,380,000 (Direct Cost: ¥82,600,000、Indirect Cost: ¥24,780,000)
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| Research Abstract |
Aiming for development of efficient synthetic routes toward natural products, which have been used as drugs, or which are expected as drug candidate, we initiated our synthetic programs. As a result, total synthesis of ecteinascidin 743, lysergic acid, huperzine A, salinosporamide and so on have been achieved. Based on the established synthetic routes, a variety of analogs of natural products and related molecules, which includes vinblastine, oseltamivir and so on have been synthesized.
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