| Project/Area Number |
20020032
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| Research Category |
Grant-in-Aid for Scientific Research on Priority Areas
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| Allocation Type | Single-year Grants |
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| Review Section |
Biological Sciences
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| Research Institution | National Institute for Physiological Sciences |
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Principal Investigator |
KAWAGUCHI Yasuo National Institute for Physiological Sciences, 大脳皮質機能研究系, 教授 (40169694)
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|---|
| Project Period (FY) |
2008 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥24,300,000 (Direct Cost: ¥24,300,000)
Fiscal Year 2009: ¥9,400,000 (Direct Cost: ¥9,400,000)
Fiscal Year 2008: ¥14,900,000 (Direct Cost: ¥14,900,000)
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| Keywords | 大脳皮質 / 局所回路 / 錐体細胞 / 介在細胞 / GABA / 層構造 / シナプス結合 / 徐波 / FS細胞 / マルティノッティ細胞 / 新皮質 / 抑制性介在ニューロン / スピンドル波 / ガンマ波 / 脱同期化 |
|---|
| Research Abstract |
Elucidation of neocortical organization principles is crucial for understanding the function of the cerebral cortex. We quantitatively identified excitatory pyramidal and GABAergic nonpyramidal cell subtypes. We found that the neuron subtypes exhibited selective connectivity and that GABAergic cells discharged during the local and global rhythms. Thus, the local synaptic organization and firing activity in the neocortex are specified according to global inter-regional circuits and their oscillatory interaction.
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