| Budget Amount *help |
¥29,250,000 (Direct Cost: ¥22,500,000、Indirect Cost: ¥6,750,000)
Fiscal Year 2010: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
Fiscal Year 2009: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
Fiscal Year 2008: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
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| Research Abstract |
To investigate the effect of magnetic fields on the cell, human umbilical vein endothelial cells (HUVECs) were exposed to a 50-Hz, 1-mT sinusoidal magnetic field. Nitric oxide (NO) production by HUVEC was estimated from the fluorescence of DAF-2, an NO indicator. The NO production of exposed and unexposed (sham) cells exhibitde statistically significant difference. This finding is consistent with previous studies in that low frequency magnetic fields affects NO production; however, our results demonstrate that in some cases, NO production was higher for the exposed group than the sham group, while in other cases the reverse was true. We suggest that the response of HUVECs to magnetic field was dependent on the condition of the cell eg., its stage in the cell cycle.
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