Interdisciplinary study for the elucidation of metalloenzyme reaction mechanism in dioxygen activation and highly efficient molecular catalyst creation

• Project/Area Number: 20200050
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
• Allocation Type: Single-year Grants
• Research Field: Chemistry related to living body; Inorganic chemistry
• Research Institution: Kyushu University
• Principal Investigator: LIU Jin-Gang Kyushu University, 先導物質化学研究所, 特任准教授 (70380540)
• Co-Investigator(Kenkyū-buntansha): OHTA Takehiro 九州大学, 先導物質化学研究所, 助教 (70509950)
• Co-Investigator(Renkei-kenkyūsha): OGURA Takashi 兵庫県立大学, 生命理学研究科, 教授 (70183770) ; YODA Yoshitaka (財)高輝度光科学研究センター, 主幹研究員 (90240366)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥30,550,000 (Direct Cost: ¥23,500,000、Indirect Cost: ¥7,050,000); Fiscal Year 2010: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000); Fiscal Year 2009: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000); Fiscal Year 2008: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
• Keywords: 酵素 / モデル化 / 生体分子 / 生体機能化学 / 生物無機化学 / 分子触媒化学 / 酸化触媒 / 有機化学 / 生体機能利用

Research Abstract

The O_2 activation/reduction reaction is one of the most important reactions involved in both of life processes and in energy converting systems such as fuel cells. This project is intended to further elucidation of the O_2 activation mechanism of metalloenzymes and creation of highly efficient molecular catalyst for O_2-reduction. Using well designed heme enzyme chemical models, we have successfully captured and fully characterized key intermediates involved in the O_2-activation processes of heme-containing enzymes by various kinds of spectroccopies as well as quantum chemical calculations. These studies have contributed significantly to the understanding of the mechanism of dioxygen activation by heme enzymes and their models. The prepared non-precious-metal catalysts will have prosperous applications as the cathode oxygen reduction reaction (ORR) catalysts in fuel cells.

Research Products

• [Journal Article] Probing dioxygen activation mechanisms in heme- containing enzymes by heme models (2011)
  • Author(s): J.-G.Liu ; Y.Naruta
  • Journal Title: Indian J.Chem. 50A Pages: 363-373
  • Peer Reviewed
• [Journal Article] Probing dioxygen activation mechanisms in heme-containing enzymes by heme models (2011)
  • Author(s): Jin-Gang Liu, Yoshinori Naruta
  • Journal Title: Indian J.Chem.Sec A Volume: 50 Pages: 363-373
  • Peer Reviewed
• [Journal Article] Formation of an End-On Ferric Peroxo Intermediate upon One-Electron Reduction of a Ferric Superoxo Heme (2010)
  • Author(s): J.-G.Liu ; Y.Shimizu ; T.Ohta ; Y.Naruta
  • Journal Title: J.Am.Chem.Soc. 132 Pages: 3672-3673
  • Peer Reviewed
• [Journal Article] Formation of an End-On Ferric Peroxo Intermediate upon One-Electron Reduction of a Ferric Superoxo Heme (2010)
  • Author(s): Liu J.-G.; Shimizu Y.: Ohta T.; Naruta Y.
  • Journal Title: J.Am.Chem.Soc. Volume: 132 Pages: 3672-3673
  • Peer Reviewed
• [Journal Article] (2009)
  • Author(s): J.-G.Liu ; T.Ohta ; Y.Yamaguchi ; T.Ogura ; S.Sakamoto ; Y.Maeda; Y.Naruta
  • Journal Title: Angew.Chem.Int.Ed. 48 Pages: 9262-9267
  • Peer Reviewed
• [Journal Article] Using Synthetic Models to Probe the O_2 Metabolic Mechanism in Heme-Containing Enzymes (2009)
  • Author(s): J.-G.Liu ; T.Ohta ; F.Tani ; Y.Naruta
  • Journal Title: G-COE Journal 3 Pages: 30-36
• [Journal Article] Synthesis and Characterization of a New Prostaglandin H Synthase Model (2009)
  • Author(s): J.J.Reddy, T.Ohta, Y.Naruta
  • Journal Title: Tetrahedron Letters 50 Pages: 3418-3421
  • Peer Reviewed
• [Journal Article] Spectroscopic Characterization of a Hydroperoxo-Heme Intermediate of a Synthetic Model : Conversion of a Side-on Peroxy to an End-on Hydroperoxy Complex (2009)
  • Author(s): Liu J.-G.; Ohta T.; Yamaguchi Y.; Ogura T.; Sakamoto S.; Maeda Y.; Naruta Y.
  • Journal Title: Angew.Chem.Int.Ed. Volume: 48 Pages: 9262-9267
  • Peer Reviewed
• [Journal Article] Using Synthetic Models to Probe the O_2, Metabolic Mechanism in Heme-Containing Enzymes (2009)
  • Author(s): Liu J.-G.; Ohta T.; Tani F.; Naruta Y.
  • Journal Title: G-COE Journal Volume: 3 Pages: 30-36
• [Journal Article] Synthesis and Characterization of a New Prostaglandin H Synthase Model (2009)
  • Author(s): J.J.Reddy, T.Ohta, Y.Naruta
  • Journal Title: Tetrahedron Letters Volume: 50 Pages: 3418-3421
  • Peer Reviewed
• [Presentation] 酸素活性化ヘム酵素モデル錯体の振動分光学的研究 (2011)
  • Author(s): 太田雄大・劉勁剛・成田吉徳・依田芳卓・斎藤真器名・小林康浩・瀬戸誠
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 横浜
  • Year and Date: 2011-03-29
• [Presentation] 新規三核化配位子を用いた多核銅酸化酵素モデル錯体の合成と性質 (2011)
  • Author(s): 安部慶郎・太田雄大・成田吉徳
  • Organizer: 日本化学会第91春季年会
  • Place of Presentation: 横浜
  • Year and Date: 2011-03-29
• [Presentation] Preparation and spectroscopic characterization of the elusive heme-nitroxyl complexes (2011)
  • Author(s): J.-G.Liu, T.Ohta, Y.Naruta
  • Organizer: The 91^<th> Annual Meeting of Chemical Society of Japan
  • Place of Presentation: Yokohama
  • Year and Date: 2011-03-26
• [Presentation] Preparation of Bio-inspired Catalyst for O_2 Reduction (2011)
  • Author(s): P.Nagaraju, J.-G.Liu, T.Ohta, Y.Naruta
  • Organizer: The 91^<th> Annual Meeting of Chemical Society of Japan
  • Place of Presentation: Yokohama
  • Year and Date: 2011-03-26
• [Presentation] Preparation and spectroscopic characterization of the elusive heme-nitroxyl complexes (2011)
  • Author(s): Jin-Gang Liu, Takehiro Ohta, Yoshinori Naruta
  • Organizer: The 91^<th> Annual Meeting of chemical Society of Japan
  • Place of Presentation: Yokohama
  • Year and Date: 2011-03-26
• [Presentation] Preparation of Bio-inspired Catalyst for O_2 Reduction (2011)
  • Author(s): Perumandla Nagaraju, Jin-Gang Liu, Takehiro Ohta, Yoshinori Naruta
  • Organizer: The 91^<th> Annual Meeting of chemical Society of Japan
  • Place of Presentation: Yokohama
  • Year and Date: 2011-03-26
• [Presentation] Bio-inspired Model Compounds for Oxygen Activation and Reduction (2011)
  • Author(s): J.-G.Liu,T.Ohta, Y.Naruta
  • Organizer: I2CNER Workshop, Kyushu University
  • Place of Presentation: Fukuoka
  • Year and Date: 2011-02-04
• [Presentation] Solution Capturing End-On Peroxo and Hydroperoxo Intermediates of Heme Enzymes (2010)
  • Author(s): J.-G.Liu, T.Ohta; Y.Shimizu,uta
  • Organizer: 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
  • Place of Presentation: Honolulu/USA
  • Year and Date: 2010-12-19
• [Presentation] Solution Capturing End-On Peroxo and Hydroperoxo Intermediates of Heme Enzymes (2010)
  • Author(s): Jin-Gang Liu, Takehiro Ohta ; Yuta Shimizu, Yoshinori Naruta
  • Organizer: 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
  • Place of Presentation: Hononlulu/USA
  • Year and Date: 2010-12-19
• [Presentation] Activation and catalytic reduction of dioxygen : Lessons from heme enzyme chemical models (2010)
  • Author(s): Y.Naruta, J.-G.Liu, T.Ohta, A.C.Maity, Y.Shimizu, F.Tani
  • Organizer: 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
  • Place of Presentation: Honolulu/USA
  • Year and Date: 2010-12-17
• [Presentation] Activation and catalytic reduction of dioxygen : Lessons from heme enzyme chemical models (2010)
  • Author(s): Yoshinori Naruta, Jin-Gang Liu, Takehiro Ohta, A.C.Maity, Y.Shimizu, F.Tani
  • Organizer: 2010 International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
  • Place of Presentation: Hononlulu/USA
  • Year and Date: 2010-12-17
• [Presentation] 酸素活性化ヘム酵素のモデル化学と分光学 (2010)
  • Author(s): 太田雄大
  • Organizer: 第一回統合物質シンポジウム「統合創製物質化学の現状と展望」
  • Place of Presentation: 京都
  • Year and Date: 2010-12-03
• [Presentation] Capturing Ferrous-Superoxo, Ferric- Peroxo and Ferric-Hydroperoxo Intermediates in Heme Models (2010)
  • Author(s): J.-G.Liu, T.Ohta ; Y.Naruta
  • Organizer: 60th Anniversary Conference on Coordination Chemistry Chem.Commun.Symposium
  • Place of Presentation: Osaka
  • Year and Date: 2010-09-28
• [Presentation] Efficient Electrocatalytic Water Oxidation with Manganese and Cobalt Porphyrin Dimers-ITO Assembly (2010)
  • Author(s): Z.N.Zaharan・太田雄大・成田吉徳
  • Organizer: 第60回錯体化学討会
  • Place of Presentation: 大阪
  • Year and Date: 2010-09-28
• [Presentation] Capturing Ferrous-Superoxo, Ferric-Peroxo and Ferric-Hydroperoxo Intermediates in Heme Models (2010)
  • Author(s): Jin-Gang Liu, Takehiro Ohta ; Yoshinori Naruta
  • Organizer: 60th Anniversary Conference on Coordination Chemistry_Chem.Commun.Symposium
  • Place of Presentation: Osaka
  • Year and Date: 2010-09-28
• [Presentation] Synthetic Heme Models Mimic the Formation of Peroxo- and Hydroperoxo- heme Intermediates Relevant to Dioxygen Activation in Heme-containing Enzymes (2010)
  • Author(s): J.-G.Liu, T.Ohta ; Y.Naruta
  • Organizer: Asian International Symposium on Inorganic Chemistry and Coordination Chemistry, Organo-metallic Chemistry
  • Place of Presentation: Osaka
  • Year and Date: 2010-03-28
• [Presentation] Spectroscopic characteri- zation of side-on and end-on (hydro)peroxo-heme intermediates (2010)
  • Author(s): J.-G.Liu ; T.Ohta ; Y.Shimizu ; Y.Naruta
  • Organizer: The 90^<th> Annual Meeting of Chemical Society of Japan
  • Place of Presentation: Osaka
  • Year and Date: 2010-03-28
• [Presentation] 三座窒素配位子配位銅錯体を有するヘム-銅二核錯体の酸素活性化反応 (2010)
  • Author(s): 太田雄大・千代健文・谷文都・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 大阪
  • Year and Date: 2010-03-28
• [Presentation] 新規銅三核化配位子誘導体を用いた多核銅酸化酵素モデル錯体の合成と性質 (2010)
  • Author(s): 安部慶郎・太田雄大・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 大阪
  • Year and Date: 2010-03-28
• [Presentation] 鉄ポルフィリンニトリド架橋錯体の合成と酸化反応 (2010)
  • Author(s): 王昂・太田雄大・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 大阪
  • Year and Date: 2010-03-28
• [Presentation] マンガンポルフィリンダイマー修飾ITO電極を用いる低過電圧での水の酸化反応 (2010)
  • Author(s): Z.N.Zahran・太田雄大・王昂・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 大阪
  • Year and Date: 2010-03-28
• [Presentation] Synthetic Heme Models Mimic the Formation of Peroxo- and Hydroperoxo-heme Intermediates Relevant to Dioxygen Activation in Heme-containing Enzymes (2010)
  • Author(s): Jin-Gang Liu, Takehiro Ohta; Yoshinori Naruta
  • Organizer: Asian International Symposium -Inorganic Chemistry and Coordination Chemistry, Organo-metallic Chemistry
  • Place of Presentation: Osaka
  • Year and Date: 2010-03-28
• [Presentation] Spectroscopic characterization of side-on and end-on (hydro)peroxo-heme intermediates (2010)
  • Author(s): Jin-Gang Liu ; Takehiro Ohta ; Yuta Shimizu ; Yoshinori Naruta
  • Organizer: The 90^<th> Annual Meeting of chemical Society of Japan
  • Place of Presentation: Osaka
  • Year and Date: 2010-03-28
• [Presentation] 三座窒素配位子配位銅錯体を有するヘム-銅二核錯体の酸素活性化反応 (2010)
  • Author(s): 太田雄大・千代健文・谷文都・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 近畿大学(大阪府)
  • Year and Date: 2010-03-28
• [Presentation] 新規銅三核化配位子誘導体を用いた多核銅酸化酵素モデル錯体の合成と性質 (2010)
  • Author(s): 安部慶郎・太田雄大・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 近畿大学(大阪府)
  • Year and Date: 2010-03-28
• [Presentation] 鉄ポルフィリンニトリド架橋錯体の合成と酸化反応 (2010)
  • Author(s): 王昂・太田雄大・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 近畿大学(大阪府)
  • Year and Date: 2010-03-28
• [Presentation] マンガンポルフィリンダイマー修飾ITO電極を用いる低過電圧での水の酸化反応 (2010)
  • Author(s): Zahran, Zaki・太田雄大・王昂・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 近畿大学(大阪府)
  • Year and Date: 2010-03-28
• [Presentation] 新規マンガンコロネットポルフィリン錯体によるプロスタグランジン-H合成酵素のモデル反応 (2010)
  • Author(s): J.J.Reddy・太田雄大・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 大阪
  • Year and Date: 2010-03-26
• [Presentation] 新規マンガンコロネットポルフィリン錯体によるプロスタグランジン-H合成酵素のモデル反応 (2010)
  • Author(s): Keddy, Jakkidi・太田雄大・成田吉徳
  • Organizer: 日本化学会第90春季年会
  • Place of Presentation: 近畿大学(大阪府)
  • Year and Date: 2010-03-26
• [Presentation] Spectroscopic Characterization of Peroxo/Hydroperoxo Heme Intermediates : Opening a Closed Side-on Peroxy to an End-on Hydroperoxy (2010)
  • Author(s): J.-G.Liu, T.Ohta ; Y.Naruta
  • Organizer: The 10^<th> International Workshop on Future Molecular Systems-Recent Development in Phorphyrin-related Chemistry
  • Place of Presentation: Fukuoka
  • Year and Date: 2010-02-19
• [Presentation] Mn-Porphyrin as a New Prostaglandin H Synthase Model : Its Catalytic Oxygenation of All-cis-Polyenes (2010)
  • Author(s): J.J.Reddy, T.Ohta, Y.Naruta
  • Organizer: 大学間連携第3回物質合成国際シンポジウム
  • Place of Presentation: 名古屋
  • Year and Date: 2010-01-07
• [Presentation] ヘムーペルオキソ種の合成と分光学による同定 (2009)
  • Author(s): 太田雄大・劉勁剛・千代健文・谷文都・成田吉徳
  • Organizer: 大学間連携第5回物質合成シンポジウム
  • Place of Presentation: 京都府
  • Year and Date: 2009-11-19
• [Presentation] ヘムーペルオキソ種の合成と分光学による同定 (2009)
  • Author(s): 太田雄大・劉勁剛・千代健文・谷文都・成田吉徳
  • Organizer: 大学間連携第5回物質合成シンポジウム
  • Place of Presentation: 京都大学(京都府宇治市)
  • Year and Date: 2009-11-19
• [Presentation] Efficient Electrolytic Water Oxidation with Manganese Porphyrin Dimer Catalysts Assembled on ITO Electrodes (2009)
  • Author(s): Z.N.Zahran, T.Ohta, A.Wang, Y.Naruta
  • Organizer: 第42回酸化反応討論会
  • Place of Presentation: 仙台
  • Year and Date: 2009-11-15
• [Presentation] 鉄ポリフィリンニトリド架橋錯体の合成と酸化反応 (2009)
  • Author(s): 王昂・太田雄大・成田吉徳
  • Organizer: 第42回酸化反応討論会
  • Place of Presentation: 仙台
  • Year and Date: 2009-11-15
• [Presentation] Efficient Electrolytic Water Oxidation with Manganese Porphyrin Dimer Catalysts Assembled on ITO Electrodes (2009)
  • Author(s): Z.N.Zahran, T.Ohta, A.Wang, Y.Naruta
  • Organizer: 第42回酸化反応討論会
  • Place of Presentation: 東北大学(仙台)
  • Year and Date: 2009-11-15
• [Presentation] 鉄ポリフィリンニトリド架橋錯体の合成と酸化反応 (2009)
  • Author(s): 王昂・太田雄大・成田吉徳
  • Organizer: 第42回酸化反応討論会
  • Place of Presentation: 東北大学(仙台)
  • Year and Date: 2009-11-15
• [Presentation] 位フッ素置換されたマンガンポルフィリン二量体の合成と高原子価種の同定 (2009)
  • Author(s): 田尾和也・太田雄大・成田吉徳
  • Organizer: 第59回錯体化学討論会
  • Place of Presentation: 長崎
  • Year and Date: 2009-09-26
• [Presentation] Synthetic heme models to mimic the formation of ferric peroxo and hydroperoxo intermediates involved in heme-containing enzymes (2009)
  • Author(s): J.-G.Liu, T.Ohta, Y.Shimizu, Y.Naruta
  • Organizer: The 59^<th> Symposium of Coordination Chemical Society of Japan
  • Place of Presentation: Nagasaki
  • Year and Date: 2009-09-26
• [Presentation] β位フッ素置換されたマンガンポルフィリン二量体の合成と高原子価種の同定 (2009)
  • Author(s): 田尾和也・太田雄大・成田吉徳
  • Organizer: 第59回錯体化学討論会
  • Place of Presentation: 長崎大学(長崎県長崎市)
  • Year and Date: 2009-09-26
• [Presentation] 鉄ポルフィリンニトリド架橋錯体の合成と酸化反応 (2009)
  • Author(s): 王昂・太田雄大・成田吉徳
  • Organizer: 第59回錯体化学討論会
  • Place of Presentation: 長崎
  • Year and Date: 2009-09-25
• [Presentation] 鉄ポルフィリンニトリド架橋錯体の合成と酸化反応 (2009)
  • Author(s): 王昂・太田雄大・成田吉徳
  • Organizer: 第59回錯体化学討論会
  • Place of Presentation: 長崎大学(長崎県長崎市)
  • Year and Date: 2009-09-25
• [Presentation] Mn-Porphyrin models of prostaglandin H synthases and their catalytic oxygenation of all-cis-polyenes (2009)
  • Author(s): J.J.Reddy, T.Ohta, Y.Naruta
  • Organizer: 第24回生体機能関連化学シンポジウム
  • Place of Presentation: 福岡
  • Year and Date: 2009-09-15
• [Presentation] Mn-Porphyrin models of prostaglandin H synthases and their catalytic oxygenation of all-cis-polyenes (2009)
  • Author(s): J.J.Reddy, T.Ohta, Y.Naruta
  • Organizer: 第24回生体機能関連化学シンポジウム
  • Place of Presentation: 九州大学(福岡)
  • Year and Date: 2009-09-15
• [Presentation] Preparation of Low-spin End-on Ferric-Peroxo and Ferric- Hydroperoxo Species by a Heme Model Complex Bearing an Imidazole Tail (2009)
  • Author(s): J.-G.Liu, T.Ohta, S.Yamaguchi, T.Ogura, Y.Naruta
  • Organizer: The 14^<th> International Conference on Biological Inorganic Chemistry (ICBIC-14)
  • Place of Presentation: Nagoya
  • Year and Date: 2009-07-27
• [Presentation] A novel dioxygen activation by a heme-copper binuclear complex (2009)
  • Author(s): T.Ohta, T.Chishiro, F.Tani, Y.Naruta
  • Organizer: 14th International Conference on Biological Inorganic Chemistry (ICBIC-14)
  • Place of Presentation: Nagoya
  • Year and Date: 2009-07-27
• [Presentation] A novel dioxygen activation by a heme-copper binuclear complex (2009)
  • Author(s): T.Ohta, T.Chishiro, F.Tani, Y.Naruta
  • Organizer: 14th International Conference on Biological Inorganic Chemistry (ICBIC 14)
  • Place of Presentation: 名古屋国際会議場(愛知県)
  • Year and Date: 2009-07-27
• [Presentation] Simulation of O_2 activation/reduction with enzyme active site models of terminal oxidases (2009)
  • Author(s): Y.Naruta, J.-G.Liu, T.Ohta, T.Ogura
  • Organizer: The 14^<th> International Conference on Biological Inorganic Chemistry (ICBIC-14)
  • Place of Presentation: Nagoya
  • Year and Date: 2009-07-26
• [Presentation] Spectroscopic Characterization of End-on Heme Peroxide and Hydroperoxide Intermediates Relevant to Dioxygen Activation Mechanism of Heme-containing Enzymes (2009)
  • Author(s): J.-G.Liu, T.Ohta ; Y.Naruta
  • Organizer: PreICBIC-Frontiers in Bioinorganic Chemistry
  • Place of Presentation: Fukuoka
  • Year and Date: 2009-07-24
• [Presentation] ヘム含有酸化酵素活性部位モデルとしてのフッ素化ポルフィリン鉄錯体の合成 (2009)
  • Author(s): 劉歓・劉勁剛・成田吉徳
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 石川県
  • Year and Date: 2009-03-29
• [Presentation] ヘム含有酸化酵素活性部位モデルとしてのフッ素化ポルフィリン鉄錯体の合成 (2009)
  • Author(s): 劉歓・劉勁剛・成田吉徳
  • Organizer: 日本化学会第89春季年会(2009)
  • Place of Presentation: 日大船橋(千葉県)
  • Year and Date: 2009-03-29
• [Presentation] カルボキシル基を導入した鉄ポルフィリンの合成および酸素との反応 (2009)
  • Author(s): 清水雄太・太田雄大・劉勁剛・谷文都・成田吉徳
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 石川県
  • Year and Date: 2009-03-28
• [Presentation] カルボキシル基を導入した鉄ポルフィリンの合成および酸素との反応 (2009)
  • Author(s): 清水雄太・太田雄大・劉勁剛・谷文都・成田吉徳
  • Organizer: 日本化学会第89春季年会(2009)
  • Place of Presentation: 日大船橋(千葉県)
  • Year and Date: 2009-03-28
• [Presentation] side-onおよびend-on型ペルオキソ-およびヒドロペルオキソヘムの合成と分光法による同定 (2009)
  • Author(s): 劉勁剛・太田雄大・山口悟・小倉尚志・成田吉徳
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 千葉県
  • Year and Date: 2009-03-27
• [Presentation] ヘム鉄・銅二核錯体における新規酸素活性化反応 (2009)
  • Author(s): 太田雄大・千代建文・谷文都・成田吉徳
  • Organizer: 日本化学会第89春季年会
  • Place of Presentation: 千葉県
  • Year and Date: 2009-03-27
• [Presentation] side-onおよびend-on型ペルオキソ-およびヒドロペルオキソヘムの合成と分光法による同定 (2009)
  • Author(s): 劉勁剛・太田雄大・山口悟・小倉尚志・成田吉徳
  • Organizer: 日本化学会第89春季年会(2009)
  • Place of Presentation: 日大船橋(千葉県)
  • Year and Date: 2009-03-27
• [Presentation] ヘム鉄・銅二核錯体における新規酸素活性化反応 (2009)
  • Author(s): 太田雄大・千代建文・谷文都・成田吉徳
  • Organizer: 日本化学会第89春季年会(2009)
  • Place of Presentation: 日大船橋(千葉県)
  • Year and Date: 2009-03-27
• [Presentation] 酸素活性化金属酵素の反応機構解明に向けてのモデル化学と分光学 (2009)
  • Author(s): 太田雄大
  • Organizer: 第3回核共鳴散乱研究会
  • Place of Presentation: 兵庫県
  • Year and Date: 2009-03-11
• [Presentation] 酸素活性化金属酵素の反応機構解明に向けてのモデル化学と分光学 (2009)
  • Author(s): 太田雄大
  • Organizer: 第3回核共鳴散乱研究会
  • Place of Presentation: SPring8萌光館(兵庫県)
  • Year and Date: 2009-03-11
• [Presentation] Preparation of Low-spin End-on Ferric-Peroxo and Ferric-Hydroperoxo Species by a Heme Model Complex Bearing an Imidazole Tail (2009)
  • Author(s): Jin-Gang Liu, Takehiro Ohta, Satoru Yamaguchi, Takashi Ogura, Yoshinori Naruta
  • Organizer: The 14^<th> International Conference on Biological Inorganic Chemistry (ICBIC-14)
  • Place of Presentation: Nagoya
• [Presentation] 生体金属のダイナミックな配位・電子構造の制御-ヘム、非ヘム鉄蛋白質を例に (2008)
  • Author(s): 太田雄大
  • Organizer: 第46回日本生物物理学会(シンポジウム:遷移金属の生物物理-若手研究者の挑戦)
  • Place of Presentation: 福岡県
  • Year and Date: 2008-12-03
• [Presentation] 生体金属のダイナミックな配位・電子構造の制御-ヘム、非ヘム鉄蛋白質を例に (2008)
  • Author(s): 太田雄大
  • Organizer: 第46回日本生物物理学会(シンポジウム : 遷移金属の生物物理-若手研究者の挑戦)
  • Place of Presentation: 福岡国際会議場(福岡県)
  • Year and Date: 2008-12-03
• [Presentation] ヘム、非ヘム鉄酵素の分光学とモデル錯体化学、物質合成研究拠点機関関連事業 (2008)
  • Author(s): 太田雄大
  • Organizer: 第3回大学間連携若手フォーラム
  • Place of Presentation: 福岡県
  • Year and Date: 2008-11-21
• [Presentation] ヘム、非ヘム鉄酵素の分光学とモデル錯体化学 (2008)
  • Author(s): 太田雄大
  • Organizer: 物質合成研究拠点機関関連事業第3回大学間連携若手フォーラム
  • Place of Presentation: 休暇村志賀島(福岡県)
  • Year and Date: 2008-11-21
• [Presentation] Using Synthetic Models to Probe the Dioxygen Metabolic Mechanism in the Terminal Enzyme of Respiratory (2008)
  • Author(s): 劉 勁剛
  • Organizer: G-COE「物質・エネルギー変換ユニット」ワークショップ
  • Place of Presentation: 福岡県
  • Year and Date: 2008-11-12
• [Presentation] Using Synthetic Models to Probe the Dioxygen Metabolic Mechanism in the Terminal Enzyme of Respiratory (2008)
  • Author(s): 劉勁剛
  • Organizer: G-COE「物質・エネルギー変換ユニット」ワークショップ
  • Place of Presentation: 海の中道ホテル(福岡県)
  • Year and Date: 2008-11-12
• [Presentation] Near-IR MCD of the Non-Heme Ferrous Active Site in Naphthalene 1,2-Dioxygenase : Correlation to Crystallography and Structural Insight into the Mechanism of Rieske Dioxygenases (2008)
  • Author(s): T.Ohta, S.Chakrabarty, J.D.Lipscomb, E.I.Solomon
  • Organizer: The 4^<th> Asian Biological Inorganic Chemistry Conference
  • Place of Presentation: Jeju/Korea
  • Year and Date: 2008-11-11
• [Presentation] Near-IR MCD of the Non-Heme Ferrous Active Site in Naphthalene 1, 2-Dioxygenase : Correlation to Crystallography and Structural Insight into the Mechanism of Rieske Dioxygenases (2008)
  • Author(s): T. Ohta・S. Chakrabarty, J.D. Lipscomb, and E.I. Solomon
  • Organizer: The 4^<th> Asian Biological Inorganic Chemistry Conference
  • Place of Presentation: Ramada Plaza Jeju(韓国)
  • Year and Date: 2008-11-11
• [Presentation] 生体金属酵素活性中心の分光学とモデル錯体化学 (2008)
  • Author(s): 太田雄大
  • Organizer: バイオミメティックス-東北大多元研、九大先導研、北大電子研合同研究会
  • Place of Presentation: 東京都
  • Year and Date: 2008-10-30
• [Presentation] 生体金属酵素活性中心の分光学とモデル錯体化学 (2008)
  • Author(s): 太田雄大
  • Organizer: バイオミメティックス-東北大多元研、九大先導研、北大電子研合同研究会
  • Place of Presentation: 霞が関コモンゲート : ナレッジスクウェア(東京都)
  • Year and Date: 2008-10-30
• [Presentation] Selective Preparation of Superoxo, Peroxo, and Hydroperoxo Species Relating to Heme-Containing Oxygenase and Peroxidase (2008)
  • Author(s): 劉勁剛・太田雄大・小倉尚志・成田吉徳
  • Organizer: 第58回錯体化学討論会
  • Place of Presentation: 石川県
  • Year and Date: 2008-09-21
• [Presentation] Selective Preparation of Superoxo, Peroxo, and Hydroperoxo Species Relating to Heme?Containing Oxygenase and Peroxidase (2008)
  • Author(s): 劉勁剛・太田雄大・小倉尚志・成田吉徳
  • Organizer: 第58回錯体化学討論会
  • Place of Presentation: 金沢大学(石川県)
  • Year and Date: 2008-09-21
• [Presentation] カルボキシル基を導入した鉄ポルフィリンの合成および酸素との反応 (2008)
  • Author(s): 清水雄太・太田雄大・劉勁剛・谷文都・成田吉徳
  • Organizer: 第58回錯体化学討論会
  • Place of Presentation: 石川県
  • Year and Date: 2008-09-20
• [Presentation] カルボキシル基を導入した鉄ポルフィリンの合成および酸素との反応 (2008)
  • Author(s): 清水雄太・太田雄大・劉勁剛・谷文都・成田吉徳
  • Organizer: 第58回錯体化学討論会
  • Place of Presentation: 金沢大学(石川県)
  • Year and Date: 2008-09-20