Surface Science and Cellular Physiology using atom beams

• Project/Area Number: 20200054
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research a proposed research project)
• Allocation Type: Single-year Grants
• Research Field: Thin film/Surface and interfacial physical properties; Cell biology
• Research Institution: Osaka Prefecture University
• Principal Investigator: UMEZAWA Kenji Osaka Prefecture University, 総合教育研究機構, 教授 (80213487)
• Co-Investigator(Kenkyū-buntansha): MIYAMOTO Kensuke 大阪府立大学, 総合教育研究機構・理学系研究科, 教授 (10209942) ; KATO Mikio 大阪府立大学, 理学系研究科, 准教授 (30204499)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥26,000,000 (Direct Cost: ¥20,000,000、Indirect Cost: ¥6,000,000); Fiscal Year 2010: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2009: ¥9,880,000 (Direct Cost: ¥7,600,000、Indirect Cost: ¥2,280,000); Fiscal Year 2008: ¥10,790,000 (Direct Cost: ¥8,300,000、Indirect Cost: ¥2,490,000)
• Keywords: 原子散乱 / 表面構造解析 / 細胞生理学 / 原子ビーム / 表面 / 原子構造解析 / 細胞生理化学

Research Abstract

This study describes a low-energy atom scattering system that was combined with a time-of-flight spectrometer for insulator surface structural analysis. Insulator surface structure is difficult to study because of the charging effects during electron or ion-beam bombardment. Our designed equipment has less than 0.1 Å spacing resolution. The effects of a high-energy proton beam applied to single E. coli cells in liquid culture medium were evaluated based on the activity of a flagellum motor and on cell growth. Average ion fluence needed to stop the flagellum motor of the tethered cells was 2.0×10^<12> protons/cm^2, which approximately corresponds to 60 kGy.

Research Products

• [Journal Article] Low Energy Ne Scattering Spectroscopy for Insulators, and Materials in the Electric/Magnetic Fields (2011)
  • Author(s): K.Umezawa, S.Nakanishi, H.Hayashi, H.Higashitsutumi, H.Nagasawa, K.Ogai, E.Narihiro
  • Journal Title: Materials Research Society(米国材料科学会) 受理
  • Peer Reviewed
• [Journal Article] The systems of TOF-low energy Ne scattering spectroscopy for insulator (2010)
  • Author(s): K.Umezawa
  • Journal Title: e-J.Surf.Sci.Nano vol.8 Pages: 194-196
  • NAID: 130004439228
  • Peer Reviewed
• [Journal Article] The Systems of TOF-low Energy Ne Atom Scattering Spectroscopy for Insulator (2010)
  • Author(s): K.Umezawa
  • Journal Title: e-Journal of Surface Science and Nanotechnology 8
  • Peer Reviewed
• [Journal Article] 紀伊半島沿岸における遊漁対象魚種の遺伝子解析:種判別マーカーの確立をめざして (2010)
  • Author(s): 加藤幹男, 藤井修平
  • Journal Title: 人間環境科学 19
  • NAID: 110007595629
  • Peer Reviewed
• [Journal Article] A Target Site for Spontaneous Insertion of IS10 Element in pUC19 DNA Located within Intrinsically Bent DNA (2009)
  • Author(s): Kobori S., Ko Y., Kato M
  • Journal Title: The Open Microbiology Journal 3 Pages: 146-150
  • Peer Reviewed
• [Journal Article] Mixed layer formation on the copper-deposited Ni(110) surface (2008)
  • Author(s): T. Fukuda, K. Iwamoto, H. Nakayama. K. Umezawa
  • Journal Title: Phys. Rev. B 78
  • Peer Reviewed
• [Journal Article] Low energy ion and atom scattering spectroscopy for surface structural analysis of single crystals and insulators (2008)
  • Author(s): K. Umezawa
  • Journal Title: Nucl. Instrum. Meth. B 266 Pages: 1892-1896
  • Peer Reviewed
• [Journal Article] TOF-ICISS and STM study on 3ML-Pd/Pt(111) surface structure (2008)
  • Author(s): K. Umezawa, E. Narihiro, Y. Ohira, M. Yoshimura
  • Journal Title: Nucl. Instrum. Meth. B 266 Pages: 1903-1907
  • Peer Reviewed
• [Presentation] MgO(111)表面原子構造に関する研究 (2011)
  • Author(s): 梅澤憲司
  • Organizer: 第58回応用物理学会関係連合講演会
  • Place of Presentation: 神奈川工科大学
  • Year and Date: 2011-03-24
• [Presentation] Real-time monitoring of Escherichia coli cells irradiated using a 2 MeV proton beams (2011)
  • Author(s): 加藤幹男、梅澤憲司
  • Organizer: 第7回アジア生物物理学会
  • Place of Presentation: New Delhi, インド国
  • Year and Date: 2011-01-30
• [Presentation] Real-time monitoring of Escherichia coli cells irradiated using a 2 MeV proton beam (2011)
  • Author(s): Mikio Kato, Walter Meissl, Kenji Umezawa, Tokihiro Ikeda, Yasunori Yamasaki, Masakazu Furutal, Tatsuo Atsumi
  • Organizer: 7th Asian Biophysics Association (ABA) Symposium & Annual Meeting of the Indian Biophysical Society (IBS)
  • Place of Presentation: インド国、New Delhi
  • Year and Date: 2011-01-30
• [Presentation] Low Energy Ne Scattering Spectroscopy for Insulators, and Materials in the Electric/Magnetic Fields (2010)
  • Author(s): 梅澤憲司
  • Organizer: Materials Research Society
  • Place of Presentation: 米国、Boston, MA
  • Year and Date: 2010-11-30
• [Presentation] Low Energy Ne Scattering Spectroscopy for Insulators, and Materials in the Electric/Magnetic Fields (2010)
  • Author(s): K.Umezawa
  • Organizer: Materials Research Society Fall Meeting
  • Place of Presentation: 米国、Boston
  • Year and Date: 2010-11-30
• [Presentation] 低速Ne原子散乱装置の開発と応用 (2010)
  • Author(s): 梅澤憲司
  • Organizer: 真空・表面科学合同講演会、第30回表面科学学術講演会、第51回真空に関する連合講演会
  • Place of Presentation: 大阪大学
  • Year and Date: 2010-11-04
• [Presentation] 低速Ne原子散乱装置の開発と応用 (2010)
  • Author(s): 梅澤憲司
  • Organizer: 真空・表面科学合同講演会、第30回表面科学学術講演会,第51回真空に関する連合講演会
  • Place of Presentation: 大阪大学吹田キャンパス
  • Year and Date: 2010-11-04
• [Presentation] Effect of proton beam irradiation through thin capillary on motility and cell growth of Escherichia coli (2010)
  • Author(s): 加藤幹男、梅澤憲司
  • Organizer: The 3^<rd> Workshop on Interaction of Ions with Insulators
  • Place of Presentation: 千葉県成田市
  • Year and Date: 2010-09-05
• [Presentation] A study of the interactions between low energy ion/neutral beams and MgO(001) (2010)
  • Author(s): 梅澤憲司
  • Organizer: The 3^<rd> Workshop on Interaction of Ions with Insulators
  • Place of Presentation: 千葉県成田市
  • Year and Date: 2010-09-05
• [Presentation] Pd/Ni(111)初期成長過程 (2010)
  • Author(s): 梅澤憲司、大平豊、原紳介、吉村雅満、福田常男
  • Organizer: 第57回応用物理学関係連合講演会
  • Place of Presentation: 東海大学
  • Year and Date: 2010-03-17
• [Presentation] Ni(110)表面上のCuのSK成長 (2010)
  • Author(s): 福田常男、安井岳史、梅澤憲司、中山弘
  • Organizer: 第57回応用物理学関係連合講演会
  • Place of Presentation: 東海大学
  • Year and Date: 2010-03-17
• [Presentation] 位相差クライオ電子顕微鏡によるDNAおよびクロマチン観察 (2009)
  • Author(s): 加藤幹男、細木直樹、刀祢重信、細野克博、蓑島伸生、清水信義、永山国昭
  • Organizer: 日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2009-12-10
• [Presentation] Structural characterization of supercoiled DNA containing a minisatellite repeat that has polypurine/polypyrimidine stretch (2008)
  • Author(s): M. Kato, T. Haku, T. Yamauchi, S. Sugiyama, K. Nagayama, N. Shiinizu
  • Organizer: 39th NIPS International Symposium & 7thOIB Symoposium Frontiers of Biological Imaging Synergy of the Advanced Techniques
  • Place of Presentation: 愛知県、岡崎コンフアレンスセンター
  • Year and Date: 2008-11-10
• [Book] ベーシックマスター細胞生物学遺伝子とタンパク質 (2009)
  • Author(s): 加藤幹男、尾張部克志、神谷律
  • Total Pages: 23
  • Publisher: オーム社
• [Remarks] ホームページ等
  • URL: http://www.osakafu-u.ac.jp/las/~umezawa
• [Remarks]
  • URL: http://www.b.s.osakafu-u.ac.jp/~mkato
• [Remarks]
  • URL: http://www.las.osakafu-u.ac.jp/las/~umezawa
• [Remarks] 宮本健助教授(分担金の使用がなかった研究分担者)
  • URL: http://www.b.s.osakafu-u.ac.jp/~mkato/
• [Remarks]
  • URL: http://www.las.osakafu-u.ac.jp/~umezawa/
• [Patent(Industrial Property Rights)] タイミングパルス発生装置 (2009)
  • Inventor(s): 梅澤憲司、中西繁光
  • Industrial Property Rights Holder: 大阪府立大学
  • Industrial Property Number: 2009-265382
  • Filing Date: 2009-11-20
• [Patent(Industrial Property Rights)] タイミングパルス発生装置 (2009)
  • Inventor(s): 梅澤憲司、中西繁光
  • Industrial Property Rights Holder: 大阪府立大学
  • Acquisition Date: 2009-01-07
• [Patent(Industrial Property Rights)] 計時装置 (2009)
  • Inventor(s): 梅澤憲司, 中西繁光
  • Industrial Property Rights Holder: 大阪府立大学
  • Industrial Property Number: 2009-265382
  • Filing Date: 2009-11-20
• [Patent(Industrial Property Rights)] タイミングパルス発生器 (2009)
  • Inventor(s): 梅澤憲司, 中西繁光
  • Industrial Property Rights Holder: 公立大学法人大阪府立大学
  • Filing Date: 2009-01-07
• [Patent(Industrial Property Rights)] タイミングパルス発生器 (2008)
  • Inventor(s): 梅澤憲司, 中西繁光
  • Industrial Property Rights Holder: 公立大学法人大阪府立大学
  • Filing Date: 2008-11-11