| Budget Amount *help |
¥36,010,000 (Direct Cost: ¥27,700,000、Indirect Cost: ¥8,310,000)
Fiscal Year 2011: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2010: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Fiscal Year 2009: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
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| Research Abstract |
Using an epilepsy rat model NER and a non-epileptic rat strain F344, we generated several congenic lines for two seizure-related QTLs. Comprehensive gene expression analyses in the brains of NER and a seizure-resistant NER. F344 double congenic strain revealed that one unknown gene and other six known genes were differentially expressed. Thus, we succeeded to disclose possible candidates for genetic factors contributing to seizure susceptibility.
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