| Co-Investigator(Renkei-kenkyūsha) |
TOKESHI Manabu 北海道大学, 工学研究院, 教授 (60311437)
KAJI Noritada 名古屋大学, 大学院・工学研究科, 准教授 (90402479)
OKAMOTO Yukihiro 名古屋大学, 革新ナノバイオデバイス研究センター, 特任講師 (50503918)
ZHANG Yong 名古屋大学, 工学研究科, 研究員 (40467329)
WANG Jun 名古屋大学, 工学研究科, 研究員 (30543532)
YASUI Takao 名古屋大学, 工学研究科, 助教 (00630584)
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| Budget Amount *help |
¥48,490,000 (Direct Cost: ¥37,300,000、Indirect Cost: ¥11,190,000)
Fiscal Year 2011: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2010: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Fiscal Year 2009: ¥11,570,000 (Direct Cost: ¥8,900,000、Indirect Cost: ¥2,670,000)
Fiscal Year 2008: ¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
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| Research Abstract |
We successfully developed novel DNA methylation analysis method. Our method elongates single DNA by flow or nanospace in the microfluidic device and detect methylation site with methylation point specific quantum-dots. Therefore, we need no troublesome procedures like PCR and can identify the location of methylation site as well as can detect methylation in single molecule level, which cannot attain by current methylation analysis method. These advantages would permit our method to be applied for medical diagnosis.
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