| Budget Amount *help |
¥37,830,000 (Direct Cost: ¥29,100,000、Indirect Cost: ¥8,730,000)
Fiscal Year 2010: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
Fiscal Year 2009: ¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2008: ¥12,220,000 (Direct Cost: ¥9,400,000、Indirect Cost: ¥2,820,000)
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| Research Abstract |
The present research has been undertaken to investigate age-related change of cognitive function in both humans and non-human primates on the basis of behavioral measurements and non-invasive neuroimaging techniques. Particularly, it has focused upon the inhibitory function and examined how response-inhibitory function declined according to aging. The study has revealed that it was not necessarily irreversible as a function of age in humans, but could be restored to the level that was equivalent to younger persons on some occasions. In such cases, neuroimaging measurements have indicated a corresponding increase of the neural activity in prefrontal regions. The experimentation with Simon task has also revealed a difference in the age-related difficulties between humans and non-human primates, and in some cases, the performance was superior in non-humans to in humans.
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