| Project/Area Number |
20245019
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Keio University |
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Principal Investigator |
SUZUKI Koji 慶應義塾大学, 理工学部, 教授 (80154540)
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| Co-Investigator(Kenkyū-buntansha) |
NIWA Osamu 独立行政法人産業技術総合研究所, 生物機能工学研究部門, 副部門長 (70392644)
HISAMOTO Hideaki 大阪府立大学, 大学院・工学研究科, 教授 (00286642)
CITTERIO Daniel 慶應義塾大学, 理工学部, 准教授 (00458952)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥49,660,000 (Direct Cost: ¥38,200,000、Indirect Cost: ¥11,460,000)
Fiscal Year 2010: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2009: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2008: ¥21,060,000 (Direct Cost: ¥16,200,000、Indirect Cost: ¥4,860,000)
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| Keywords | 蛍光プローブ / ケミカルバイオロジーツール / 化学発光分子 / 分子イメージング / MRIプローブ / ケミカルバイオロジー / ハロタグリガンド結合リポソーム / 分子プローブ / イメージング / 化学発光 / 画像診断 / 蛍光色素 |
|---|
| Research Abstract |
Several new types of revolutionary fluorescent probes have been developed, in order to satisfy the increasing demands and interest in biological substance imaging, as well as for the development of fluorescence imaging technology. However, unique chemical sensing probes, which are required for one of the cutting-edge topics in bioimaging, have not been well established. In this study, several new types of fluorescent/luminescent probes, redox probes and nuclear magnetic resonance probes (MRI probes), which have unique properties, were designed and synthesized for their application to bioimaging of substances in living cells and organs.
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