Three dimensional design of nanostructures for label-free biosensing
| Project/Area Number |
20246008
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thin film/Surface and interfacial physical properties
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| Research Institution | Tohoku University |
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Principal Investigator |
NIWANO Michio 東北大学, 電気通信研究所, 教授 (20134075)
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| Co-Investigator(Kenkyū-buntansha) |
HIRANO Ayumi 東北大学, 大学院・医工学研究科, 准教授 (80339241)
KIMURA Yasuo 東北大学, 電気通信研究所, 准教授 (40312673)
AONUMA Yuki 東北大学, 電気通信研究所, 助教 (80582262)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥50,570,000 (Direct Cost: ¥38,900,000、Indirect Cost: ¥11,670,000)
Fiscal Year 2010: ¥9,230,000 (Direct Cost: ¥7,100,000、Indirect Cost: ¥2,130,000)
Fiscal Year 2009: ¥19,760,000 (Direct Cost: ¥15,200,000、Indirect Cost: ¥4,560,000)
Fiscal Year 2008: ¥21,580,000 (Direct Cost: ¥16,600,000、Indirect Cost: ¥4,980,000)
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| Keywords | 表面 / 表面ナノ構造 / バイオ界面 / 非標識光計測 / 非標識光 / 赤外分光 / 表面ナノ構浩 |
|---|
| Research Abstract |
The purpose of this study is development of a new biosensing technology based on the combination of silicon nanotechnology and design of bio-interfaces. We have examined formation of artificial bilayer lipid membranes (BLMs)in microfabricated apertures and nanoporous structures. We succeeded in preparation of free-standing BLMs having dramatically improved membrane stability. Such stable BLMs will open up variety of applications. In addition, we have examined efficient formation of nano structures as a new platform for nano-bioelectronics. Our approaches are useful for innovation of novel nano-recognition interfaces and bioelectronics based on the design of nanostructure interfaces.
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Report
(4 results)
Research Products
(202 results)
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[Presentation] 半導体微細センサーの開発2009
Author(s)
大嶋梓, 平野愛弓, 青戸孝至, 平良祐, 木村康男, 庭野道夫
Organizer
日本分析化学会第加工技術を利用した人工脂質二分子膜58年会
Place of Presentation
札幌
Year and Date
2009-09-26
Related Report
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[Presentation] Planar Lipid Bilayers for L-Glutamate Sensing2009
Author(s)
A. Hirano-Iwata, A. Oshima, T. Taira, K. Aoto, Y. Kimura, and M. Niwano
Organizer
International Symposium innovative Nanoscience of Supermolecular Motor Proteins Working in Biomembranes
Place of Presentation
Kyoto
Year and Date
2009-09-10
Related Report
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