• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Analysis of multi-oscillator structure of biological clock

Research Project

Project/Area Number 20249010
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Environmental physiology (including Physical medicine and Nutritional physiology)
Research InstitutionHokkaido University

Principal Investigator

HONMA Ken-Ichi  Hokkaido University, 大学院・医学研究科, 特任教授 (40113625)

Co-Investigator(Renkei-kenkyūsha) TANAHASHI Yuhsuke  北海道大学, 大学院・医学研究科, 助教 (50374228)
NISHIDE Shinya  北海道大学, 大学院・医学研究科, 助教 (40451398)
NAKAMUEA Tomoko  北海道大学, 大学院・医学研究科, 特任助教 (30451397)
YAMADA Yoshiko  北海道大学, 大学院・医学研究科, 学術研究員 (10466451)
YASUDA Tsubura  北海道大学, 大学院・医学研究科, 技術職員 (50399820)
SHUDO Miwako  北海道大学, 大学院・医学研究科, 技術補助員 (20466452)
YAMANAKA Yuhjiro  北海道大学, 大学院・医学研究科, 助教 (20528343)
HASHIMOTO Satoko  北海道大学, 大学院・医学研究科, 博士研究員 (80374247)
TOKUMARU Nobuko  北海道大学, 大学院・医学研究科, 博士研究員 (90567439)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥51,220,000 (Direct Cost: ¥39,400,000、Indirect Cost: ¥11,820,000)
Fiscal Year 2010: ¥11,440,000 (Direct Cost: ¥8,800,000、Indirect Cost: ¥2,640,000)
Fiscal Year 2009: ¥11,440,000 (Direct Cost: ¥8,800,000、Indirect Cost: ¥2,640,000)
Fiscal Year 2008: ¥28,340,000 (Direct Cost: ¥21,800,000、Indirect Cost: ¥6,540,000)
Keywords生物時計 / 時計遺伝子 / システム / 行動リズム / リズム同調 / 光周期 / 末梢時計 / フィードバック
Research Abstract

Oscillating neurons in the suprachiasmatic nucleus (SCN), the center of biological clock, constructs more than one regional pacemakers of different characteristics through mutual synchronization. The roles of regional pacemakers depend on the area of SCN, and their interaction determines the length of activity period, showing seasonal changes in behavioral rhythms. The function of biological clock is disrupted by restricted daily feeding or methamphetamine treatment, which is supposed to be due to desynchronization between the central and peripheral clocks. The peripheral clock(s) regulating behavioral rhythms is suggested to reside in the midbrain.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (80 results)

All 2010 2009 2008 Other

All Journal Article (37 results) (of which Peer Reviewed: 28 results) Presentation (32 results) Book (8 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results) (of which Overseas: 1 results)

  • [Journal Article] Physical exercise accelerates re-entrainment of human sleep-wake cycle but not of plasma melatonin rhythm to 8 h phase-advanced sleep schedule.2010

    • Author(s)
      Yamanaka Y., S.Hashimoto, Y.Tanahashi, S.Nishide, S.Honma, K.Honma
    • Journal Title

      Am J Physiol Regul Integr Comp Physiol 298

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Loss of circadian rhythm and light-induced suppression of pineal melatonin levels in Cry1 and Cry2 double-deficient mice.2010

    • Author(s)
      Yamanaka Y., Suzuki Y., Todo T, Honma K, Honma S.
    • Journal Title

      Genes to Cells 10

      Pages: 1063-1071

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Self-sustained circadian rhythm in cultured human mononuclear cells isolated from peripheral blood2010

    • Author(s)
      T.Ebisawa
    • Journal Title

      Neurosci.Res.

      Volume: 66 Pages: 223-227

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Physical exercise accelerates entrainment of human sleep-wake cycle but not of plasma melatonin rhythm of 8-h phase-advanced sleep schedule2010

    • Author(s)
      Y.Yamanaka
    • Journal Title

      Am J Physiol

      Volume: 298

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Loss of circadian rhythm and light-induced suppression of pineal melatonin levels in Cry1 and Cry2 double-deficient mice.2010

    • Author(s)
      Y.Yamanaka
    • Journal Title

      Genes to Cells

      Volume: 15 Pages: 1063-1071

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multichannel perfusion culture bioluminescence reporter system for lone-term detection in living cells2010

    • Author(s)
      T.Watanabe
    • Journal Title

      Analytical Biochemistry

      Volume: 402 Pages: 107-109

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 睡眠の神経生理学2010

    • Author(s)
      本間研一
    • Journal Title

      臨床精神医学

      Volume: 39 Pages: 493-497

    • Related Report
      2010 Annual Research Report
  • [Journal Article] In vitro differentiation of chondrogenic ATDC5 is enhanced by culturing on synthetic hydrogels with various charge densities2010

    • Author(s)
      Kwon HJ
    • Journal Title

      Acta Bionaterialia 6

      Pages: 494-501

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-sustained circadian rhythm in cultured human mononuclear cells isolated from peripheral blood2010

    • Author(s)
      Ebisawa T
    • Journal Title

      Neuerosci Res 66

      Pages: 223-227

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Physical exercise accelerates reentrainment of human sleep-wake cycle but not of plasma melatonin rhythm to 8-h phase-advanced sleep schedule2010

    • Author(s)
      Yamanaka Y
    • Journal Title

      Am J Physiol 298

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The SCN-independent clocks, methamphetamine and food restriction.2009

    • Author(s)
      Honma K, Honma S.
    • Journal Title

      Eur J Neurosci. 30

      Pages: 1707-1717

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of intracranial surgery on pineal lipid droplets, on other structures, and on melatonin secretion.2009

    • Author(s)
      Kuroshima M., G.Takahashi, T.Suzuki, S.Hashimoto, K.Honma, T.Kachi
    • Journal Title

      Anal Sci Int 84

      Pages: 17-26

    • NAID

      10025549982

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Liver X factors (LXRαand LXRβ) are potent regulators for hepatic DEC1 expression.2009

    • Author(s)
      Noshiro M., E.Usui, T.Kawamoto, F.Sato, A.Nakashima, T.Ueshima, K.Honda, K.Fujimoto, S.Honma, K.Honma, M.Makishima, Y.Kato
    • Journal Title

      Genes to Cells 14

      Pages: 29-40

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] The SCN-independent clocks, methamphetamine and food restriction2009

    • Author(s)
      Honma K
    • Journal Title

      Eur J Neurosci 30

      Pages: 1707-1717

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] In vivo bioluminescence imaging of bone marrow-derived cells in brain inflamation2009

    • Author(s)
      Akimoto H
    • Journal Title

      Biochemical Biophysical Research Communication 380

      Pages: 844-849

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of intracranial surgery on pineal lipid droplets on other structures, and on melatonin secretion2009

    • Author(s)
      Kurushima M
    • Journal Title

      Anal Sci Int 84

      Pages: 17-26

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ラット視交叉上核における時計遺伝子rPer1及びrPer2発現細胞数の時空間解析2009

    • Author(s)
      徳丸信子
    • Journal Title

      北海道医学雑誌 84

      Pages: 327-337

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 睡眠・覚醒・生体リズムの調節機構2009

    • Author(s)
      山仲勇二郎
    • Journal Title

      日本臨床 67

      Pages: 1475-1482

    • Related Report
      2009 Annual Research Report
  • [Journal Article] 時差症候群・交代勤務睡眠障害のバイオロジー2009

    • Author(s)
      山仲勇二郎
    • Journal Title

      睡眠医療 3

      Pages: 379-382

    • Related Report
      2009 Annual Research Report
  • [Journal Article] The liver X receptors (LXRα and LXRβ) are potent regulators for hepatic Decl expression2009

    • Author(s)
      Noshiro M
    • Journal Title

      Genes to Cells 14

      Pages: 29-40

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 睡眠の分子生物学2009

    • Author(s)
      本間研一
    • Journal Title

      Clinical Neuroscience 27

      Pages: 141-144

    • Related Report
      2008 Annual Research Report
  • [Journal Article] On the role of calcium and potassium currents in circadian modulation of firing rate in rat suprachiasmatic nucleus neurons : Multielectrode dish analysis.2008

    • Author(s)
      Kononenko N., S.Honma, F.D. Dudek, K.Honma
    • Journal Title

      Neurosci.Research 62

      Pages: 51-57

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] The circadian pacemaker in the cultured suprachiasmatic nucleus from pup mice is highly sensitive to external perturbation.2008

    • Author(s)
      Nishide S., S.Honma, K.Honma
    • Journal Title

      Eur J Neurosci 27

      Pages: 2686-2690

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Scheduled exposures to a novel environment with a running-wheel differentially accelerate re-entrainment of mice peripheral clocks to new light-dark cycles.2008

    • Author(s)
      Yamanaka Y., S.Honma, K.Honma
    • Journal Title

      Genes to Cells 13

      Pages: 497-507

    • NAID

      120002911943

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Circadian behavioral rhythms in Cry1/Cry2 doubledeficient mice.2008

    • Author(s)
      Honma S., T.Yasuda, A.Yasui, G.T.J. van der Horst, K.Honma
    • Journal Title

      J Biol Rhythm 23

      Pages: 91-94

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] A TTX sensitive local circuit is involved in the expression of PK2 and BDNF circadian rhythms in the mouse suprachiasmatic nucleus.2008

    • Author(s)
      Baba K., D.Ono, S.Honma, K.Honma
    • Journal Title

      Eur J Neurosci 27

      Pages: 909-916

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] On the role of calcium and potassium currents in circadian modulation of firing rate in rat suprachiasmatic nucleus neurons : Multielectrode dish analysis2008

    • Author(s)
      Kononenko NI
    • Journal Title

      Neurosci Res. 62

      Pages: 51-57

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The circadian pacemaker in the cultured suprachiasmatic nucleus from pup mice is highly sensitive to external perturbation2008

    • Author(s)
      Nishide S
    • Journal Title

      Eur. J. Neurosci. 27

      Pages: 2686-2690

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Scheduled exposures to a novel environment with a running-wheel differentially accelerate re-entrainment of mice peripheral clocks to new light-dark cycles2008

    • Author(s)
      Yamanaka, Y
    • Journal Title

      Genes to Cells, 13

      Pages: 497-507

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Circadian behavioral rhythms in Cry1 / Cry2 double-deficient mice induced by me thamphetamine2008

    • Author(s)
      Honma, S
    • Journal Title

      J Bilogical Rhythms 23

      Pages: 91-94

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clock mechanisms for seasonal adaptation : Morning and evening oscillators in the sunrachiasmatic nucleus2008

    • Author(s)
      Honma, S
    • Journal Title

      Sleep BioL Rhythms 6

      Pages: 84-90

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A TTX sensitive local circuit is involved in the expression of PK2 and BDNF circadian rhythms in the mouse suprachiasmatic nucleus2008

    • Author(s)
      Baba, K
    • Journal Title

      Eur. J. Neurosci 27

      Pages: 909-916

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 生体リズムの分子機構2008

    • Author(s)
      吉川朋子
    • Journal Title

      日本臨床 933

      Pages: 90-95

    • Related Report
      2008 Annual Research Report
  • [Journal Article] モデル動物を使った睡眠研究. ヒト型睡眠の特徴とそのモデル化2008

    • Author(s)
      増渕悟
    • Journal Title

      細胞工学 27

      Pages: 456-460

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 真夜中の人体の生理2008

    • Author(s)
      山仲勇二郎
    • Journal Title

      Journal of Integrated Medicine 18

      Pages: 820-825

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 睡眠と生体リズム, 概日リズムの位相制御2008

    • Author(s)
      山仲勇二郎
    • Journal Title

      脳21 11

      Pages: 26-31

    • Related Report
      2008 Annual Research Report
  • [Journal Article] 生体リズムの基礎知識2008

    • Author(s)
      本間研一
    • Journal Title

      日本臨床 66

      Pages: 45-52

    • Related Report
      2008 Annual Research Report
  • [Presentation] Sleep and Circadian Rhythms2010

    • Author(s)
      K.Honma
    • Organizer
      11^<th> Annual Meeting of Sleep Medicine, Ozsetleri
    • Place of Presentation
      Antaiya, Turkey
    • Year and Date
      2010-11-09
    • Related Report
      2010 Final Research Report
  • [Presentation] Sleep and Circadian Rhythms2010

    • Author(s)
      K.Honma
    • Organizer
      11^<th> Annual Meeting of Sleep Medicine
    • Place of Presentation
      Ozsetleri, Antalya, Turkey 招待講演
    • Year and Date
      2010-11-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] In vivo bioluminescence reporter gene imaging of the olfactory bulb in the mouse brain2010

    • Author(s)
      T.Hamada
    • Organizer
      2010 World Molecular Imaging Congress
    • Place of Presentation
      京都国際会館
    • Year and Date
      2010-09-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] Spatiotemporal analysis of Clock gene Per1 and Per2 expression in the rat suprachiasmatic nucleus.2010

    • Author(s)
      N.Tokumaru, S.Honma, K.Honma
    • Organizer
      The 87^<th> Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      Morioka
    • Year and Date
      2010-05-21
    • Related Report
      2010 Final Research Report
  • [Presentation] Perturbation of circadian oscillation in cultured mouse suprachiasmatic nucleus by protein synthesis inhibitor2010

    • Author(s)
      S.Nishide, S.Honma, K.Honma
    • Organizer
      The 87^<th> Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      Morioka
    • Year and Date
      2010-05-21
    • Related Report
      2010 Final Research Report
  • [Presentation] Acceleration of photic entrainment by non-photic time cues in mouse : effects of exercise and/or stress on central and peripheral clocks2010

    • Author(s)
      Y.Yamanaka, S.Honma, K.Honma
    • Organizer
      The 87^<th> Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      Morioka
    • Year and Date
      2010-05-21
    • Related Report
      2010 Final Research Report
  • [Presentation] Spatiotemporal analysis of Clock gene Per1 and Per2 expression in the rat suprachiasmatic nucleus.2010

    • Author(s)
      N.Tokumaru
    • Organizer
      The 87^<th> Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      盛岡市民文化ホール
    • Year and Date
      2010-05-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Perturbation of circadian oscillation in cultured mouse suprachiasmatic nucleus by protein synthesis inhibitor2010

    • Author(s)
      S.Nishide
    • Organizer
      The 87^<th> Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      盛岡市民文化ホール
    • Year and Date
      2010-05-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Acceleration of photic entrainment by non-photic time cues in mouse : effects of exercise and/or stress on central and peripheral clocks2010

    • Author(s)
      Y.Yamanaka
    • Organizer
      The 87^<th> Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      盛岡市民文化ホール
    • Year and Date
      2010-05-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] A two-oscillator hypothesis2010

    • Author(s)
      K.Honma
    • Organizer
      Turkish-Japanese Sleep Forum
    • Place of Presentation
      Crowne Plaza Hotel, Izmir Turkey 招待講演
    • Year and Date
      2010-05-04
    • Related Report
      2010 Annual Research Report
  • [Presentation] Rapid shift of social schedule induces an internal desynchronization between sleep-wake cycle and plasma melatonin rhythm.2009

    • Author(s)
      Yamanaka Y.
    • Organizer
      The ASRS summit and symposium on sleep research and medicine, Abst., p.31
    • Place of Presentation
      Nago (Japan)
    • Year and Date
      2009-10-31
    • Related Report
      2010 Final Research Report
  • [Presentation] Two differential molecular mechanisms for circadian oscillation in the suprachiasmatic nucleus.2009

    • Author(s)
      Ono D. Honma S., Honma K.
    • Organizer
      ASRS summit and symposium on sleep research and medicine, Abst., p.53
    • Place of Presentation
      Nago (Japan)
    • Year and Date
      2009-10-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Molecular events associated with resetting the circadian oscillation by protein synthesis inhibitor in mouse suprachiasmatic nucleus.2009

    • Author(s)
      Nishida S., Honma S., Honma K.
    • Organizer
      ASRS summit and symposium on sleep research and medicine, Abst., p.54
    • Place of Presentation
      Nago (Japan)
    • Year and Date
      2009-10-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Seasonality in sleep and wakefulness.2009

    • Author(s)
      Honma S., Yoshikawa T., Hashimoto S, Honma K.
    • Organizer
      6th Congress of Asian Sleep Research Society, Symposium 'Sleep as a Biological Rhythm', Abstract p.99
    • Place of Presentation
      Osaka (Japan)
    • Year and Date
      2009-10-26
    • Related Report
      2010 Final Research Report
  • [Presentation] Seasonality in sleep and wakefulness.2009

    • Author(s)
      Honma S
    • Organizer
      6th Congress of Asian Sleep Research Society
    • Place of Presentation
      大阪市 国際会議場
    • Year and Date
      2009-10-26
    • Related Report
      2009 Annual Research Report
  • [Presentation] 生活スケジュールの変化がヒトの睡眠に及ぼす影響2009

    • Author(s)
      本間研一
    • Organizer
      日本睡眠学会第34回定期学術集会
    • Place of Presentation
      大阪市 国際会議場
    • Year and Date
      2009-10-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Non-photic time cues phase-dependently accelerate phase-shifts of mouse peripheral clocks.2009

    • Author(s)
      Yamanaka Y., Honma S., Honma K.
    • Organizer
      XI Congress of the European Biological Rhythms Society, Symposium 'Entrainment by non-photic cues', Abst.P.58
    • Place of Presentation
      Strasburg (France)
    • Year and Date
      2009-08-25
    • Related Report
      2010 Final Research Report
  • [Presentation] Molecular mechanism of circadian oscillation reset by prolonged treatment of cycloheximide in mouse suprachiasmatic nucleus.2009

    • Author(s)
      Nishide S., Honma S., Yamada Y., Honma K.
    • Organizer
      XI Congress of the European Biological Rhythms Society, Poster Session, Abst.P.124
    • Place of Presentation
      Strasburg (France)
    • Year and Date
      2009-08-25
    • Related Report
      2010 Final Research Report
  • [Presentation] Organization of the hierarchical multi-oscillator system in the suprachiasmatic nucleus.2009

    • Author(s)
      Honma K
    • Organizer
      XI Congress of the European Biological Rhythms Society
    • Place of Presentation
      フランス ストラースブルグ大学
    • Year and Date
      2009-08-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Non-photic time cues phase-dependently accelerate phase-shifts of mouse peripheral clocks.2009

    • Author(s)
      Yamanaka Y
    • Organizer
      XI Congress of the European Biological Rhythms Society
    • Place of Presentation
      フランス ストラースブルグ大学
    • Year and Date
      2009-08-25
    • Related Report
      2009 Annual Research Report
  • [Presentation] Circadian firing rhythms in Cry1/Cry2 double-deficient mice in the cultured suprachiasmatic nucleus.2009

    • Author(s)
      Ono D., Honma S., Honma K.
    • Organizer
      XI Congress of the European Biological Rhythms Society, Symposium 'Exploring spatoptemporal organization of SCN circuits', Abst.P.64
    • Place of Presentation
      Strasburg (France)
    • Year and Date
      2009-08-24
    • Related Report
      2010 Final Research Report
  • [Presentation] Circadian firing rhythms in Cry1/Cry2 double-deficient mice in the cultured suprachiasmatic nucleus.2009

    • Author(s)
      Ono D
    • Organizer
      XI Congress of the European Biological Rhythms Society
    • Place of Presentation
      フランス ストラースブルグ大学
    • Year and Date
      2009-08-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] SCN-independent clocks : a possible mechanism of non-photic entrainment in humans.2009

    • Author(s)
      Honma K.
    • Organizer
      International Symposium on Biological Rhythm, Abstr..14
    • Place of Presentation
      Sapporo (Japan)
    • Year and Date
      2009-08-03
    • Related Report
      2010 Final Research Report
  • [Presentation] SCN-independent clocks : a possible mechanism of non-photic entrainment in humans2009

    • Author(s)
      Honma K
    • Organizer
      International Symposium on Biological Rhythm
    • Place of Presentation
      札幌市 北海道大学
    • Year and Date
      2009-08-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] Molecular mechanisms of terminating and restarting circadian rhythms in the mouse suprachiasmatic nucleus.2009

    • Author(s)
      Nishide S., Honma S., Yamada Y., Hamada T., Honma K.
    • Organizer
      36^<th> International Congress of Physiological Sciences, Poser Session
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2009-08-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Effects of ambient temperature during maternal deprivation on circadian rhythms of neonatal rats.2009

    • Author(s)
      Yoshikawa T., Matsuno A., Yamanaka Y., Nishide S., Honma S., Honma K.
    • Organizer
      36^<th> International Congress of Physiological Sciences, Poser Session
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2009-08-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Re-entrainment of circadian rhythms after 8 h advanced light-dark cycles depends on the timing of exposure to novel environment in mice.2009

    • Author(s)
      Yamanaka Y., Honma S., Honma K.
    • Organizer
      36^<th> International Congress of Physiological Sciences, Poser Session
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2009-08-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Differential responses of the circadian rhythms in mouse suprachiasmatic nucleus cells to protein synthesis inhibitor, cyclohezimide.2009

    • Author(s)
      Ono D., Honma S., Honma K.
    • Organizer
      36^<th> International Congress of Physiological Sciences, Poser Session
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2009-08-01
    • Related Report
      2010 Final Research Report
  • [Presentation] Clock mechanisms in mammals encoding photoperiods.2009

    • Author(s)
      Honma S., Yoshikawa T., Honma K.
    • Organizer
      36^<th> International Congress of Physiological Sciences, Whole-day Symposium 'Temporal organization of physiology and behavior'
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2009-07-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Circadian organization in humans : is there any oscillator(s) for behavioral rhythms independent of those in the SCN?2009

    • Author(s)
      Honma K.
    • Organizer
      36^<th> International Congress of Physiological Sciences, Whole-day Symposium 'Temporal organization of physiology and behavior'
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2009-07-30
    • Related Report
      2010 Final Research Report
  • [Presentation] Circadian organization in humans : is there any oscillator(s)for behavioral rhythms independent of those in the SCN?2009

    • Author(s)
      Honma K
    • Organizer
      36^<th> International Congress of Physiological Sciences
    • Place of Presentation
      京都市 国際会議場
    • Year and Date
      2009-07-30
    • Related Report
      2009 Annual Research Report
  • [Presentation] サマータイム制度 : 生体リズムと睡眠に及ぼす影響2008

    • Author(s)
      本間研一
    • Organizer
      日本睡眠学会第33回定期学術集会
    • Place of Presentation
      郡山市ビックパレット福島
    • Year and Date
      2008-06-25
    • Related Report
      2008 Annual Research Report
  • [Book] Bioluminescent Imaging for Assessing Heterogenous Cell Functions in the Mammalian Central Circadian Clock.((eds) N.Tamaki and Y. Kuge)(Molecular Imaging for Integrated Medical Therapy and Drug Development)2010

    • Author(s)
      Honma S., T.Yoshikawa, S.Nishide, D.Ono, K.Honma
    • Publisher
      Springer, Tokyo
    • Related Report
      2010 Final Research Report
  • [Book] Molecular Imaging for Integrated Medical Therapy and Drug Development2010

    • Author(s)
      S.Honma
    • Total Pages
      264
    • Publisher
      Springer
    • Related Report
      2010 Annual Research Report
  • [Book] Molecular Imaging for Integrated Medical Therapy and Drug Development2010

    • Author(s)
      Honma S
    • Total Pages
      264
    • Publisher
      Springer
    • Related Report
      2009 Annual Research Report
  • [Book] からだと温度の事典2010

    • Author(s)
      山仲勇二郎
    • Total Pages
      640
    • Publisher
      朝倉書店
    • Related Report
      2009 Annual Research Report
  • [Book] 生命の束石2009

    • Author(s)
      本間研一
    • Total Pages
      320
    • Publisher
      マイクロ印刷
    • Related Report
      2009 Annual Research Report
  • [Book] 睡眠学2009

    • Author(s)
      本間研一
    • Total Pages
      735
    • Publisher
      朝倉書店
    • Related Report
      2008 Annual Research Report
  • [Book] 睡眠と健康2008

    • Author(s)
      本間研一
    • Total Pages
      143
    • Publisher
      メデイコピア
    • Related Report
      2008 Annual Research Report
  • [Book] 時間生物学事典2008

    • Author(s)
      本間研一
    • Total Pages
      326
    • Publisher
      朝倉書店
    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://babu.med.hokudai.ac.jp/~phys~1w/

    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] ターゲット位置追跡装置およびターゲット発光検出装置2010

    • Inventor(s)
      石川正純、浜田俊幸、本間研一、本間さと
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2010-245624
    • Filing Date
      2010-11-01
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] ターゲット位置追跡装置およびターゲット発光検出装置2010

    • Inventor(s)
      石川正純
    • Industrial Property Rights Holder
      北海道大学
    • Industrial Property Number
      2010-245624
    • Filing Date
      2010-11-01
    • Related Report
      2010 Annual Research Report
    • Overseas

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi