|Budget Amount *help
¥50,700,000 (Direct Cost: ¥39,000,000、Indirect Cost: ¥11,700,000)
Fiscal Year 2012: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2011: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2010: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Fiscal Year 2009: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2008: ¥22,750,000 (Direct Cost: ¥17,500,000、Indirect Cost: ¥5,250,000)
In order to establish novel molecular forensic diagnosis, we focus on cytokines/chemokines as the marker of systemic vital reactions, and examined the systemic dynamics of cytokines/chemokines in the various models of diseases, drug intoxication, and injuries, which are often encountered in forensic practices. We could find the several candidates cytokines/chemokines as key players in the models of sepsis, drowning, drug intoxication (acetaminophen, arsenite, cisplatin, chlorpromazine), deep vein thrombosis, acute pancreatitis, traumatic shock, and ischemia-reperfusion skeletal muscle injury, and identify specifics markers for molecular forensic diagnosis.