| Project/Area Number |
20300106
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Bioinformatics/Life informatics
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| Research Institution | The University of Tokyo |
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Principal Investigator |
HAGIYA Masami The University of Tokyo, 大学院・情報理工学系研究科, 教授 (30156252)
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| Co-Investigator(Kenkyū-buntansha) |
TANAKA Fumiaki 東京大学, 大学院・情報理工学系研究科, 助教 (50456159)
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| Research Collaborator |
HIRABAYASHI Miki 情報通信研究機構, 研究員
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2010: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2009: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2008: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Keywords | DNA計算 / DNAナノテク / 三次元ナノ構造 / 分子システム / AFM測定 / DNAナノテクノロジー / 三次元ナノ構造体 / アゾベンゼン / DNAコンピューティング / 3次元ナノ構造 / 自動設計 |
|---|
| Research Abstract |
We developed a "molecular combination dial," which can be controlled by the order of multiple inputs, and a "nano-cage," which can be combined with the dial.
In detail, we successfully constructed DNA capsules that can be broken by UV light (nano-cage) by inserting a photo-controllable molecule (azobenzene) into DNA buckyballs developed by Mao. Moreover, we developed a molecular machine that can be controlled by the order of UV light irradiation and addition of ATP (molecular combination dial), with the use of a computer program for automatic design.
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