Budget Amount *help |
¥14,560,000 (Direct Cost: ¥11,200,000、Indirect Cost: ¥3,360,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2008: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
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Research Abstract |
To reconstruct three-dimensional(3D) structure of proteins, we have developed newly 3D reconstruction algorithm and a high-contrast detection system of the biological samples. Our 3D reconstruction method was composed with the modified Simulated-Annealing algorithm with the high accuracy classification method of the class averages from the protein images by the transmission-electron microscopy. This method enables automatically 3D reconstruction from the protein images. Furthermore, we developed high-contrast and low-damage 3D detection system. This system contains a linear array PD system and new 3D reconstruction method.
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