Development of Bioassay System with Microwell Slide Towards High throughput Single Cell Analysis
| Project/Area Number |
20300149
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (B)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Biomedical engineering/Biological material science
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
OHASHI Toshiro Hokkaido University, 大学院・工学研究院, 教授 (30270812)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SATO Masaaki 東北大学, 大学院・医工学研究科, 教授 (30111371)
SAKAMOTO Naoya 東北大学, 大学院・工学研究科, 助教 (20361115)
MAEDA Eijiro 北海道大学, 大学院・工学研究院, 助教 (20581614)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥19,500,000 (Direct Cost: ¥15,000,000、Indirect Cost: ¥4,500,000)
Fiscal Year 2010: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2008: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
|
|---|
| Keywords | バイオメカニクス / 単一細胞診断 / マイクロウェル / マイクロフルイディクス / バイオチップ / バイオMEMS / マクロウェル / マクロフルディクス |
|---|
| Research Abstract |
Since most laboratory bioassays used for cell analysis are designed to measure average effects on cell population, it is difficult to study characteristics of individual cells such as patient's tumor cell samples in a high throughput manner. Recently, a novel microwell slide that allows several thousands of single cells to be addressed to an exact position, cultured for weeks, and treated separately in high throughput has been developed. In this project we have proposed a bioassay system consisting of an active microfluidic device integrated on the microwell plate for improved control of, and new applications for the single cells.
|
Report
(4 results)
Research Products
(10 results)
