The neuromodulated sterility treatment using by sacral surface electrical stimulation

• Project/Area Number: 20300192
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Tohoku University
• Principal Investigator: OGURA Takahide Tohoku University, 大学院・医学系研究科, 助教 (10312688)
• Co-Investigator(Renkei-kenkyūsha): HANDA Yasunobu 東北大学, 大学院・医学系研究科, 名誉教授 (00111790) ; SEKI Kazunori 東北大学, 大学院・医学系研究科, 准教授 (20206618) ; MURAKAMI Takashi 滋賀医科大学, 大学院・医学系研究科, 教授 (20240666)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥19,240,000 (Direct Cost: ¥14,800,000、Indirect Cost: ¥4,440,000); Fiscal Year 2010: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000); Fiscal Year 2009: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000); Fiscal Year 2008: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
• Keywords: 電気刺激 / ニューロモジュレーション / MRI / 仙骨部電気刺激 / 子官機能不全 / 形態解析 / 動態解析 / 血流解析 / Cine mode MRI / 不妊症 / 子宮機能不全

Research Abstract

The peak power and frequency of uterine peristalses after sacral surface electrical stimulation (ssES) treatment decreased markedly in comparison with that measured before ssES the day of embryo transfer (ET). However, there is no change of the PGF_<2α> density in urine before and after ssES. The suppression effect of uterine peristalses may be an effect of neuromodulation by electrical stimulation. This electrical neuromodulation may be an effective method to induce uterine relaxation for ET.

Research Products

• [Journal Article] Change of perfusion after performing CWC exercise for the patients wit h walking disability. (2010)
  • Author(s): Takaaki Sekiya
  • Journal Title: Proc.of ISEK 2010 Volume: 2010(1) Pages: 522-525
• [Journal Article] Uterine relaxation by sacral surface electrical stimulation on the day of embryo transfer (2009)
  • Author(s): O Fujii, T Murakami, H Murakawa, Y Terada, T Ogura, N Yaegashi
  • Journal Title: Fertility and Sterility Vol.90, No.4 Pages: 1240-1242
  • Peer Reviewed
• [Journal Article] 拡散係数測定の基準物質に関する基礎的研究 (2009)
  • Author(s): 佐々木洋介、小倉隆英, 他
  • Journal Title: 東北大学医学部保健学科紀要 Vol.18、No.1 Pages: 37-44
  • Peer Reviewed
• [Journal Article] MR高速撮像とMRアンギオグラフィー (2009)
  • Author(s): 町田好男、小倉隆英, 他
  • Journal Title: 東北大学医学部保健学科紀要 Vol.18、No.1 Pages: 1-7
  • Peer Reviewed
• [Journal Article] 拡散係数測定の基準物質選択に関する基礎的研究 (2009)
  • Author(s): 佐々木洋介
  • Journal Title: 東北大学医学部保健学科紀要 18 Pages: 37-44
  • Peer Reviewed
• [Journal Article] MR高速撮像とMRアンギオグラフィー (2009)
  • Author(s): 町田好男
  • Journal Title: 東北大学医学部保健学科紀要 18 Pages: 1-7
  • Peer Reviewed
• [Presentation] Change of perfusion after performing CWC exercise for the patients with walking disability (2010)
  • Author(s): T.SEKIYA, T.OGURA, K.SEKI, Y.HANDA
  • Organizer: ISEK
  • Place of Presentation: Aalborg
  • Year and Date: 2010-06-17
• [Presentation] Change of brain perfusion after performing CWC exercise for the patien is with walking disability. (2010)
  • Author(s): Takaaki Sekiya
  • Organizer: International Society of Electrophysiology and Kin esiology
  • Place of Presentation: Aalborg, Denmark
  • Year and Date: 2010-06-17
• [Presentation] Effect of electrical stimulation for the abdomen (2009)
  • Author(s): M.SASAKI, T.OGURA, Y.HANDA
  • Organizer: 10th ACPT
  • Place of Presentation: Tokyo
  • Year and Date: 2009-09-01
• [Presentation] Effect of electrical stimulation for the abdomen in the inactive elderly (2009)
  • Author(s): M.SASAKI
  • Organizer: 10th ACPT
  • Place of Presentation: Tokyo
  • Year and Date: 2009-09-01
• [Presentation] Analysis of the changes to the uterine function induced by sacral surface electrical stimulation using for magnetic resonance imaging (2008)
  • Author(s): Takahide Ogura, Naoshi Sato, Kayoko Suzuki, Takashi Murakami, Kazunori Seki, Yasunobu Handa
  • Organizer: ISRN
  • Place of Presentation: Soul
  • Year and Date: 2008-06-01
• [Book] 脊髄電気刺激療法(森本昌宏ed.) (2008)
  • Author(s): 半田康延、関和則、小倉隆英、村上節, 他
  • Publisher: 克誠堂出版
• [Remarks] ホームページ等