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Development of brain-computer interface for motor and verbal functions based on signal analysis of electrocorticogram

Research Project

Project/Area Number 20300199
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKinki University

Principal Investigator

KATO Amami  Kinki University, 医学部, 教授 (00233776)

Co-Investigator(Kenkyū-buntansha) SHIBATA Tomohiro  奈良先端科学技術大学院大学, 情報科学研究科, 准教授 (40359873)
HIRATA Masayuki  大阪大学, 大学院・医学系研究科, 助教 (30372626)
Co-Investigator(Renkei-kenkyūsha) NAKANO Naoki  近畿大学, 医学部, 講師 (60258027)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
Fiscal Year 2010: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Keywords事象関連脱同期 / 皮質脳波 / 脳-コンピュータインターフェイス / 微小神経回路 / てんかん源性 / 脳磁図 / 言語企図 / 言語賦活 / 運動企図 / 運動賦活
Research Abstract

Brain-computer interface(BCI)implies decoding the (human) intension from the brain activity by means of computer. We have developed BCI by analyzing electrocorticograms obtained performing either motor or verbal tasks with the cooperation of neurosurgical patients who have been temporarily implanted subdural grid electrodes. As a result, we obtained 86.6±5.8% of discriminating performance concerning motor function (three different hand movements) and 53-63% of classifying performance, which is much higher than the chance level (33%) concerning verbal intension (silent reading of three vowels).

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (57 results)

All 2011 2010 2009 2008 Other

All Journal Article (35 results) (of which Peer Reviewed: 28 results) Presentation (16 results) Book (2 results) Remarks (4 results)

  • [Journal Article] Reorganization of sensorimotor function after functional hemispherectomy studied using near-infrared spectroscopy : a case report.2011

    • Author(s)
      Honda N
    • Journal Title

      Pediatric Neurosurgery

      Volume: (in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Reorganization of sensorimotor function after functional hemispherectomy studied using near-infrared spectroscopy2010

    • Author(s)
      Honda N, Matuoka T, Sawada Y, Nakano N, Suwen L, Higashimoto Y, Fukuda K, Ohgi S, Kato A
    • Journal Title

      a case report. Pediatric Neurosurgery 46

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] ヒト皮質脳波からの黙読母音の判別に関する研究2010

    • Author(s)
      池田純起,柴田智広,露口尚弘,中野直樹,原嘉信,岡田理恵子,池田和司,加藤天美
    • Journal Title

      電子情報通信学会技術研究報告.NC,ニューロコンピューティング 110

      Pages: 45-50

    • NAID

      110007890689

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Bonnet Bypass to Proximal Trunk of Middle Cerebral Artery with a Radial Artery Interposition Graft2010

    • Author(s)
      Sanada Y, Iwaisako K, Kamiyama H, Yoshimine T, Kato A
    • Journal Title

      Technical Note. Minim Invas Neurosurg 53

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Training in endoscopic endonasal transsphenoidal surgery using a skull model and eggs.2010

    • Author(s)
      Okuda T, Kataoka K, Kato A
    • Journal Title

      Acta Neurochir (Wien). 152

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 日本におけるてんかんの実態キャリーオーバー患者の問題2010

    • Author(s)
      大塚頌子,赤松直樹,加藤天美,木下真幸,久保田英幹,小西徹,笹川睦男
    • Journal Title

      てんかん研究 27

      Pages: 402-407

    • NAID

      10025993702

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fluorescence-guided surgery of metastatic brain tumors using fluorescein sodium.2010

    • Author(s)
      Okuda T, Kataoka K, Yabuuchi T, Yugami H, Kato A
    • Journal Title

      J Clin Neurosci 17

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Training in endoscopic endonasal transsphenoidal surgery using a skullmodel and eggs2010

    • Author(s)
      Okuda T
    • Journal Title

      Acta Neurochir(Wien)

      Volume: 152 Pages: 1801-1804

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fluorescence-guided surgery of metastatic brain tumors using fluoresceinsodium2010

    • Author(s)
      Okuda T
    • Journal Title

      J Clin Neurosci

      Volume: 17 Pages: 118-121

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Language dominance and mapping based on neuromagnetic oscillatory changes : comparison with invasive procedures2010

    • Author(s)
      Hirata M
    • Journal Title

      J Neurosurg 112

      Pages: 528-538

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Movement induces suppression of interictal spikes in sensorimotor neocortical epilepsy.2009

    • Author(s)
      Yanagisawa T, Hirata M, Kishima H, Goto T, Saitoh Y, Oshino S, Hosomi K, Kato A, Yoshimine T
    • Journal Title

      Epilepsy Res 87

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Surgical technique for a cystic-type metastatic brain tumor : transformation to a solid-type tumor using hydrofiber dressing.2009

    • Author(s)
      Okuda T, Teramoto Y, Yugami H, Kataoka K, Kato A
    • Journal Title

      Surg Neurol 72(6)

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 責任血管が三叉神経を貫通する特発性三叉神経痛の微小血管減圧術2009

    • Author(s)
      渡邉啓,中西欣弥,中野直樹,岩倉倫裕,加藤天美
    • Journal Title

      脳神経外科(ISSN 0301-2603) 37

      Pages: 255-259

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural decoding using gyral and intrasulcal electrocorticograms.2009

    • Author(s)
      Yanagisawa T, Hirata M, Saitoh Y, Kato A, Shibuya D, Kamitani Y, Yoshimine T
    • Journal Title

      Neuroimage 45(4)

      Pages: 1099-1106

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Treatment of leptomeningeal carcinomatosis from gastric cancer.2009

    • Author(s)
      Okuda T, Kataoka K, Kato A
    • Journal Title

      Gan To Kagaku Ryoho 36(4)

      Pages: 599-603

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] フェニトイン注射薬の使用実態調査:日本てんかん学会評議員・会員を対象としたアンケート調査2009

    • Author(s)
      大澤真木子,井上有史,亀山茂樹,加藤天美,松浦雅人,永井利三郎,大塚頌子,渡辺雅子
    • Journal Title

      てんかん研究 27

      Pages: 51-58

    • NAID

      10025993659

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Language dominance and mapping based on neuromagnetic oscillatory changes : comparison with invasive procedures.2009

    • Author(s)
      Hirata M, Goto T, Barnes G, Umekawa Y, Yanagisawa T, Kato A, Oshino S, Kishima H, Hashimoto N, Saitoh Y, Tani N, Yorifuji S, Yoshimine T
    • Journal Title

      J Neurosurg 112

      Pages: 528-538

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Serial volumetric assessment of the natural history and growth pattern of incidentally discovered meningiomas.2009

    • Author(s)
      Hashiba T, Hashimoto N, Izumoto S, Suzuki T, Kagawa N, Maruno M, Kato A, Yoshimine T
    • Journal Title

      J Neurosurg 110

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] てんかん性異常波伝播の脳磁図解析2009

    • Author(s)
      加藤天美,押野悟,平田雅之
    • Journal Title

      臨床脳波 51

      Pages: 410-417

    • Related Report
      2010 Final Research Report
  • [Journal Article] Cutting Edge脳神経外科手術を変えるデジタル技術の展開(特集脳神経外科-最新ギアの最前線)2009

    • Author(s)
      加藤天美,鎌田恭輔,宝金清博
    • Journal Title

      Medical torch 5

      Pages: 8-19

    • NAID

      40016760524

    • Related Report
      2010 Final Research Report
  • [Journal Article] Movement induces suppression of interictal spikes in sensorimotor neocortical epilepsy2009

    • Author(s)
      Yanagisawa T
    • Journal Title

      Epilepsy Res 87

      Pages: 12-17

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neural decoding using gyral and intrasulcal electrocorticograms2009

    • Author(s)
      Yanagisawa T
    • Journal Title

      Neurolmage 45

      Pages: 1099-1106

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] MRI-Based Correction for Partial Volume Effect Improves Detectability of Intractable Epileptogenic Foci on I-123 Iomazenil Brain SPECT Images.2008

    • Author(s)
      Kato H, Shimosegawa E, Oku N, Kitagawa K, Kishima H, Saitoh Y, Kato A, Yoshimine T, Hatazawa J
    • Journal Title

      J Nucl Med 49

      Pages: 383-389

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Management of skull base defect with bFGF after extensive skull base surgery-Two-case report-.2008

    • Author(s)
      Hashimoto N, Taniguchi M, Kato A, FujimotoY, Yoshimine T
    • Journal Title

      Minim Invas Neurosurg 51

      Pages: 136-139

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Ipsilateral motor-related hyperactivity in patients with cerebral occlusive vascular disease.2008

    • Author(s)
      Oshino S, Kato A, Hirata M, Kishima H, Saitoh Y, Fujinaka T, Yoshimine T
    • Journal Title

      Stroke 39

      Pages: 2769-2775

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 悪性リンパ腫におけるfluorescein術中蛍光診断の有用性2008

    • Author(s)
      奥田武司,片岡和夫,加藤天美
    • Journal Title

      脳神経外科 36

      Pages: 1001-1004

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 対側病変を有する左半球広範性皮質形成異常に伴った難治性West症候群のてんかん外科治療2008

    • Author(s)
      青天目信,下野九理子,沖永剛志,今井克美,神尾範子,最上友紀子,新谷研,貴島晴彦,加藤天美,永井利三郎,大園恵一
    • Journal Title

      19

      Pages: 45-55

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Distorted depth perception under the microscope : compensation by surgical navigator and image projection.2008

    • Author(s)
      加藤天美
    • Journal Title

      Acta Med Kinki Univ 33

      Pages: 1-5

    • NAID

      120005736764

    • Related Report
      2010 Final Research Report
  • [Journal Article] 視床下核刺激パラメーター変更の効果発現から考察した進行性パーキンソン病における刺激のメカニズム2008

    • Author(s)
      中野直樹,渡邉啓,中西欣弥,加藤天美
    • Journal Title

      Functional neurosurgery. 47

      Pages: 14-15

    • NAID

      10024369468

    • Related Report
      2010 Final Research Report
  • [Journal Article] 痙縮に対するITB療法による治療2008

    • Author(s)
      内山卓也,住井利寿,湯上春樹,中村英剛,山田恭史,加藤天美
    • Journal Title

      Functional neurosurgery. 47

      Pages: 66-67

    • NAID

      10024369587

    • Related Report
      2010 Final Research Report
  • [Journal Article] 脳深部刺激療法(<小特集>バイオニックヒューマン生体機械融合インタフェース~)2008

    • Author(s)
      中野直樹,加藤天美
    • Journal Title

      映像情報メディア 62

      Pages: 846-848

    • Related Report
      2010 Final Research Report
  • [Journal Article] 求心路遮断性疼痛に対する運動野刺激療法,脊髄刺激療法の作用機序2008

    • Author(s)
      貴島晴彦,齋藤洋一,平山東,平田雅之,押野悟,谷直樹,細見晃一,加藤天美,吉峰俊樹
    • Journal Title

      CI研究 29

      Pages: 153-158

    • NAID

      10021281858

    • Related Report
      2010 Final Research Report
  • [Journal Article] MRI-Based Correction for Partial Volume Effect Improves Detectability of Intractable Epileptogenic Foei on I-123 Iomazenil Brain SPECT Images.2008

    • Author(s)
      Kato H
    • Journal Title

      J Nucl Med 49

      Pages: 383-389

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ipsilateral motor-related hyperactivity in patients with cerebral occlus ive vascular disease.2008

    • Author(s)
      Oshino S
    • Journal Title

      Stroke 39

      Pages: 2769-2775

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Management of skull base defect with bFGF after extensive skull base surgery -Two-case report-.2008

    • Author(s)
      Kato A
    • Journal Title

      Minim Invas Neurosurg 51

      Pages: 136-139

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Is additional amygdalo-hippocampectomy necessary for intractable epilepsy associated with temporal lesions2010

    • Author(s)
      Kishima H
    • Organizer
      64th Annual Meeting and 3rd Biennial North American Regional Congress
    • Place of Presentation
      San Antonio, TX, USA
    • Year and Date
      2010-12-05
    • Related Report
      2010 Annual Research Report
  • [Presentation] Language function associated with phonemic and context cue in verbal fluency tasks : an fMRI study.2010

    • Author(s)
      Okada R
    • Organizer
      29th International Congress of Clinical Neurophysiology
    • Place of Presentation
      Kobe Japan
    • Year and Date
      2010-10-28
    • Related Report
      2010 Final Research Report
  • [Presentation] Only a few ECoG electrodes can discriminate words in mind.2010

    • Author(s)
      池田純起
    • Organizer
      Neuro 2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-04
    • Related Report
      2010 Final Research Report
  • [Presentation] ヒト大脳・小脳皮質スライスの細胞構築と多電極システムによる神経活動の解析2010

    • Author(s)
      山崎裕介
    • Organizer
      第33回日本神経科学大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-04
    • Related Report
      2010 Final Research Report
  • [Presentation] ヒト皮質脳波からの黙読母音の判別に関する研究2010

    • Author(s)
      池田純起
    • Organizer
      包括型脳科学研究推進支援ネットワーク2010夏のワークショップ
    • Place of Presentation
      札幌
    • Year and Date
      2010-07-27
    • Related Report
      2010 Final Research Report
  • [Presentation] Less ECoG Electrodes Discriminate Words in Mind Better.2010

    • Author(s)
      Ikeda S
    • Organizer
      The fifth international workshop on Statistical Analysis of Neuronal Data
    • Place of Presentation
      Pittsburgh, USA
    • Year and Date
      2010-05-20
    • Related Report
      2010 Final Research Report
  • [Presentation] A Study on Discriminating Words Read Silently from Human Electrocorticogram.2010

    • Author(s)
      Ikeda S
    • Organizer
      2010 RISP International Workshop on Nonlinear Circuits, Communications and Signal Processing
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2010-03-03
    • Related Report
      2010 Final Research Report
  • [Presentation] Functional hemispherectomy by vertical method using neuronavigation, 3rd Asian Epilepsy Surgery2009

    • Author(s)
      Kato A
    • Organizer
      3rd Asian Epilepsy Surgery Congress
    • Place of Presentation
      Osaka
    • Related Report
      2009 Annual Research Report
  • [Presentation] Less invasive surgical treatment for widespread or multilober cortical dysplasia.2008

    • Author(s)
      Kato A
    • Organizer
      2nd Asian Epilepsy Surgery Congress
    • Place of Presentation
      Shijiazhuang, China
    • Year and Date
      2008-10-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] P2-11対側に二次性焦点を形成した下側頭回神経節細胞腫による難治性てんかんの一例(症例報告)2008

    • Author(s)
      林淑文
    • Organizer
      第42回日本てんかん学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-30
    • Related Report
      2010 Final Research Report
  • [Presentation] P1-42抗てんかん剤によってPisa症候群を呈した1例2008

    • Author(s)
      中野直樹
    • Organizer
      第42回日本てんかん学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-30
    • Related Report
      2010 Final Research Report
  • [Presentation] O1-1てんかん焦点診断におけるI-123iomazenil SPECTとFDG-PETの比較2008

    • Author(s)
      細見晃一
    • Organizer
      第42回日本てんかん学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 02-20前方脳梁離断術前後での発作間欠期脳磁図の変化2008

    • Author(s)
      押野悟
    • Organizer
      第42回日本てんかん学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 02-25テレビ会議システムを用いたてんかん外科診療ネットワークの構築2008

    • Author(s)
      加藤天美
    • Organizer
      第42回日本てんかん学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 02-28側頭葉てんかん手術の社会生活状況に及ぼす影響2008

    • Author(s)
      貴島晴彦
    • Organizer
      第42回日本てんかん学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-30
    • Related Report
      2010 Final Research Report
  • [Presentation] 02-57てんかん外科のための脳波律動変化を用いた脳機能マッピング2008

    • Author(s)
      平田雅之
    • Organizer
      第42回日本てんかん学会
    • Place of Presentation
      東京
    • Year and Date
      2008-09-30
    • Related Report
      2010 Final Research Report
  • [Book] Progress in Epileptic Disorders Vol.6(Ikeda A, Inoue Y, eds.)(Motor Control and Epilepsy-Functional Restoration after Epilepsy Surgery Involving Sensorimotor Cortex-)2008

    • Author(s)
      Kato A, Oshino S, Hirata M, Kishima H, Yanagisawa T, Taniguchi M, Hosomi K, Goto T, Yoshimine T, Okinaga T, Shimono K, Imai K
    • Publisher
      John Libbey Eurotext, France
    • Related Report
      2010 Final Research Report
  • [Book] Progress in Epileptic Disorders Vol. 6 PP139-149 Motor Control and Epilepsy -Fundional Restoration after Epilepsy Surgery Involving Sensorimotor Cortex-.2008

    • Author(s)
      Kato A
    • Total Pages
      291
    • Publisher
      John Libbey Eurotext, France
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.med.kindai.ac.jp/nouge/

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://WWW.med.kindai.ac.jp/nouge/

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.kindai.ac.jp/nouge/

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.med.kindai.ac.jp/nouge/

    • Related Report
      2008 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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