| Project/Area Number |
20300220
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Shimane University |
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Principal Investigator |
YAMAGUCHI Syuhei (2010) Shimane University, 医学部, 教授 (80135904)
益田 順一 (2008-2009) Shimane University, 医学部, 教授 (70173747)
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| Co-Investigator(Kenkyū-buntansha) |
MASUDA Junichi 島根大学, 医学部, 教授 (70173747)
NABIKA Toru 島根大学, 医学部, 教授 (50180534)
SHIWAKU Kuninori 島根大学, 医学部, 教授 (10108384)
山口 修平 島根大学, 医学部, 教授 (80135904)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2010: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2009: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2008: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
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| Keywords | 保健健康管理 / 遺伝子多型 / コホート / ソーシャルキャピタル / 横断研究 / 生活習慣病 / 健康調査 / メタボリック症候群 / 遺伝子多型解析 / 食事習慣 / 生活満足度 / 認知機能 / 危険因子 / 疫学 / 肥満 / 頸動脈エコー |
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| Research Abstract |
In this study, we performed health examinations in a rural area, in which effects of single-nucleotide polymorphisms (SNPs) and social capital on life-style associated diseases were evaluated. We established a large cohort of 4000 participants with several valuable phenotypes for a future longitudinal study. In addition, we found unique relationships between social capital and hypertension as well as between combinations of multiple SNPs and oxidative stress.
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