| Project/Area Number |
20310035
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Risk sciences of radiation/Chemicals
|
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| Research Institution | Nagoya City University (2009-2010)
Nagoya University (2008) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TAKAGI Kenji 名古屋大学, 医学部, 准教授 (80126870)
UEYAMA Jun 名古屋大学, 医学部, 助教 (00397465)
NAKAJIMA Tamie 名古屋大学, 大学院・医学系研究科, 教授 (10020794)
|
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| Co-Investigator(Renkei-kenkyūsha) |
ITO Yuki 名古屋市立大学, 大学院・医学研究科, 助教 (80452192)
SHIBATA Eiji 愛知医科大学, 医学部, 教授 (90206128)
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| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2010: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2009: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2008: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
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| Keywords | 人体有害物質 / 衛生 / 環境 / 社会医学 / リスク評価 / 農薬 / 殺虫剤 / 有機リン / ピレスロイド / 生物学的モニタリング / 尿 / 代謝物 |
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| Research Abstract |
We developed and established highly sensitive methods of measuring urinary metabolites of organophosphorus and pyrethroid insecticides. The established methods were applied to general population and pesticide sprayers to evaluate their exposure. Furthermore, the relationship between metabolite body burden and male reproductive dysfunction was investigated. It was suggested that evaluation of single insecticide metabolite might lead to underestimation of risk of pesticide exposure.
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