| Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2010: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2009: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2008: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
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| Research Abstract |
We have succeeded in developing a technique to culture myotubes on a fibrin gel sheet. The prepared myotube culture on the hydrogel stably contract on electrical stimulation for more than 1 week. We also succeeded in preparing PEDOT microelectrodes on hydrogels like collagen and agarose, that shows surface resistivity of 50 Ω/□. The combination of these two hydrogel sheets, on which myotubes and PEDOT are micropatterned, provides a totally contractile biochip that will be a powerful tool for the muscle-targeted drug development.
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