Microelectrode Techniques for Cellular Engineering
Project/Area Number |
20310070
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Microdevices/Nanodevices
|
Research Institution | Tohoku University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
KAJI Hirokazu 東北大学, 大学院・工学研究科, 准教授 (70431525)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥19,110,000 (Direct Cost: ¥14,700,000、Indirect Cost: ¥4,410,000)
Fiscal Year 2010: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2009: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Fiscal Year 2008: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
|
Keywords | 細胞チップ / 筋肉細胞 / 導電性高分子 / マイクロ・ナノデバイス / 細胞・組織 / バイオチップ / バイオ・チップ |
Research Abstract |
We have succeeded in developing a technique to culture myotubes on a fibrin gel sheet. The prepared myotube culture on the hydrogel stably contract on electrical stimulation for more than 1 week. We also succeeded in preparing PEDOT microelectrodes on hydrogels like collagen and agarose, that shows surface resistivity of 50 Ω/□. The combination of these two hydrogel sheets, on which myotubes and PEDOT are micropatterned, provides a totally contractile biochip that will be a powerful tool for the muscle-targeted drug development.
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Report
(4 results)
Research Products
(52 results)