Advances in Studies on Multicopper Reductases
Project/Area Number |
20350078
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Chemistry related to living body
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Research Institution | Osaka University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
NOJIRI Masaki 大阪大学, 大学院・理学研究科, 助教 (20333346)
|
Co-Investigator(Renkei-kenkyūsha) |
SAKURAI Takeshi 金沢大学, 大学院・自然科学研究科, 教授 (90116038)
|
Project Period (FY) |
2008 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2010: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2009: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2008: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
|
Keywords | 亜硝酸還元酵素 / 銅タンパク質 / 脱窒菌 / ニキビ菌 / 海洋性好冷菌 / X線結晶構造解析 / シトクロム c / ブルー銅タンパク質 / 組換体 / シックロムc / シトクロムc |
Research Abstract |
For the biological and environmental importance, there have been many reports on Cu-containing nitrite reductases (NIRs), which are trimers containing two copper ions in each monomer. We have recently found new hexameric and trimeric NIRs having an extra domain at the N- and C-terminus, respectively. In this project, the structure-function relationships of the new NIRs from a propionibacterium and a marine psychrophilic bacterium have been studied.
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Report
(4 results)
Research Products
(54 results)
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[Presentation] Role of the N-terminal cupredoxin domain of a hexameric nitrite reductase2010
Author(s)
Ikebuchi, S., Koteishi, H., Yamaguchi, K., Suzuki, S., Nojiri, M.
Organizer
The International Chemical Congress of Pacific Basin Societies
Place of Presentation
Hawaii Convention Center, Hawaii, USA
Year and Date
2010-12-15
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