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Development and Systemization of Environment-Compatible and Photo-Actuatable Hydrogels

Research Project

Project/Area Number 20350110
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Polymer/Textile materials
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

SUMARU Kimio  National Institute of Advanced Industrial Science and Technology, 幹細胞工学研究センター, 主任研究員 (40344436)

Co-Investigator(Kenkyū-buntansha) TAKAGI Toshiyuki  独立行政法人産業技術総合研究所, 幹細胞工学研究センター, 主任研究員 (10248065)
SUGIURA Shinji  独立行政法人産業技術総合研究所, 幹細胞工学研究センター, 主任研究員 (10399496)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2010: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2008: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Keywordsゲル / 光アクチュエータゲル / スピロピラン / マイクロ流体システム / 光応答性バルブ / 光酸発生剤 / 光応答性ブルブ
Research Abstract

We developed microfluidic systems composed of photo-shrinkable hydrogel sheets, and demonstrated independent control of 10 microvalves and on-demand control of fluid mixing. Also we developed a photo-responsive hydrogel which returns from photo-induced shrinking state to the stable swollen state about 10 times faster than existing ones requiring more than 1 hour, and demonstrated photo-controllable micro-manipulation of small object on the hydrogel sheet. Further we developed a hydrogel functionalized with photo-acid-generating groups, and fabricated a photo-writable microfluidic chip which can be used in wide pH conditions.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (37 results)

All 2011 2010 2009

All Journal Article (8 results) (of which Peer Reviewed: 5 results) Presentation (23 results) Book (6 results)

  • [Journal Article] Fast-reversible light-driven hydrogels consisting of spirobenzopyran- functionalized poly(N- isopropylacrylamide)2011

    • Author(s)
      Taku Satoh, Kimio Sumaru, Toshiyuki Takagi, Toshiyuki Kanamori
    • Journal Title

      Soft Matter in press

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Isomerization of spirobenzopyrans bearing electron-donating and electron- withdrawing groups in acidic aqueous solutions2011

    • Author(s)
      Taku Satoh, Kimio Sumaru, Toshiyuki Takagi, Katsuki Takai, Toshiyuki Kanamori
    • Journal Title

      Phys.Chem.Chem.Phys. 13

      Pages: 7322-7329

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Isomerization of spirobenzopyrans bearing electron-donating and electron-withdrawing groups in acidic aqueous solutions2011

    • Author(s)
      佐藤琢、須丸公雄、高木俊之、高井克毅、金森敏幸
    • Journal Title

      Physical Chemistry Chemical Physics

      Volume: 13 Pages: 7322-7329

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 光応答収縮ゲルシートを用いたマイクロ流体制御システム2010

    • Author(s)
      須丸公雄
    • Journal Title

      高分子

      Pages: 718-719

    • NAID

      10026584872

    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Journal Article] 光応答収縮ゲルによるマイクロ流路のオンデマンド光制御2010

    • Author(s)
      須丸公雄, 杉浦慎治, 高木俊之, 金森敏幸
    • Journal Title

      化学工学 74

      Pages: 332-332

    • NAID

      10026871453

    • Related Report
      2010 Final Research Report
  • [Journal Article] 光応答収縮ゲルによるマイクロ流路のオンデマンド光制御2010

    • Author(s)
      須丸公雄、杉浦慎治、高木俊之、金森敏幸
    • Journal Title

      化学工学

      Volume: 74 Pages: 322-322

    • NAID

      10026871453

    • Related Report
      2010 Annual Research Report
  • [Journal Article] On-demand microfluidic control by micropatterned light irradiation of a photoresponsive hydrogel sheet2009

    • Author(s)
      Shinji Sugiura, Andras Szilagyi, Kimio Sumaru, Koji Hattori, Toshiyuki Takagi, Genoveva Filipcsei, Miklos Zrinyi, Toshiyuki Kanamori
    • Journal Title

      Lab Chip 9

      Pages: 196-198

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] On-demand microfluidic control by micropatterned light irradiationof a photoresponsive hydrogel sheet2009

    • Author(s)
      S. Sugiura, A. Szilagyi, K. Sumaru*, K. Hattori, T. Takagi, G. Fillipcsei, M. Zrinyi, T. Kanamori
    • Journal Title

      Lab on a Chip 9

      Pages: 196-198

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] スピロピラン修飾ハイドロゲルからなる高速光駆動アクチュエータ2011

    • Author(s)
      佐藤琢、須丸公雄、高木俊之、高井克毅、金森敏幸
    • Organizer
      第22回高分子ゲル研究討論会
    • Place of Presentation
      東京大学山上会館
    • Year and Date
      2011-01-13
    • Related Report
      2010 Annual Research Report
  • [Presentation] Kimio Sumaru, Szilagyi Andras, Taku Satoh, Shinji Sugiura, Toshiyuki Takagi, Koji Hattori, Toshiyuki Kanamori2010

    • Author(s)
      Kimio Sumaru, Szilagyi Andras, Taku Satoh, Shinji Sugiura, Toshiyuki Takagi, Koji Hattori, Toshiyuki Kanamori
    • Organizer
      6th International Symposium on Organic Photochromism
    • Place of Presentation
      Yokohama
    • Year and Date
      2010-10-20
    • Related Report
      2010 Final Research Report
  • [Presentation] Substitution Effect on Isomerization of Spiropyran in Acidic Aqueous System2010

    • Author(s)
      Taku Satoh, Kimio Sumaru, Toshiyuki Takagi, Katsuki Takai, Toshiyuki Kanamori
    • Organizer
      6th International Symposium on Organic Photochromism
    • Place of Presentation
      Yokohama
    • Year and Date
      2010-10-20
    • Related Report
      2010 Final Research Report
  • [Presentation] Spiropyran-Functionalized Hydrogels as Photo-Responsive Mechanical Actuators2010

    • Author(s)
      須丸公雄、Szilagyi Andras、佐藤琢、杉浦慎治、高木俊之、服部浩二、金森敏幸
    • Organizer
      6th International Symposium on Organic Photochromism
    • Place of Presentation
      日石横浜ホール
    • Year and Date
      2010-10-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Substitution Effect on Isomerization of Spiropyran in Acidic Aqueous System2010

    • Author(s)
      佐藤琢、須丸公雄、高木俊之、高井克毅、金森敏幸
    • Organizer
      6th International Symposium on Organic Photochromism
    • Place of Presentation
      日石横浜ホール
    • Year and Date
      2010-10-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Photo-Responsive Polyion Complexation of Spiropiran-Functionalized Polymer2010

    • Author(s)
      須丸公雄、高木俊之、高井克毅, 金森敏幸
    • Organizer
      6th International Symposium on Organic Photochromism
    • Place of Presentation
      日石横浜ホール
    • Year and Date
      2010-10-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Photo-Responsive Cell Culture Substrate Composed of Spiropyran-Functionalized Polymer2010

    • Author(s)
      須丸公雄、菊池鏡子、高木俊之、大島裕貴、金森敏幸
    • Organizer
      6th International Symposium on Organic Photochromism
    • Place of Presentation
      日石横浜ホール
    • Year and Date
      2010-10-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] 高速駆動が可能なスピロピラン修飾光応答ハイドロゲル2010

    • Author(s)
      佐藤琢、須丸公雄、高木俊之、高井克毅、金森敏幸
    • Organizer
      第59回高分子討論会
    • Place of Presentation
      北海道大学
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] スピロピランの構造設計に基づく光応答収縮ハイドロゲルの高性能化2010

    • Author(s)
      佐藤琢、須丸公雄、高木俊之、高井克毅、金森敏幸
    • Organizer
      第59回高分子学会年次大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] フォトクロミックハイドロゲルの光応答物性に及ぼすスピロピラン誘導体構造の影響2010

    • Author(s)
      佐藤琢, 須丸公雄, 高木俊之, 高井克毅, 金森敏幸
    • Organizer
      第21回 高分子ゲル研究討論会
    • Place of Presentation
      東京都
    • Year and Date
      2010-01-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] On-Demand Control of Microfluidic System by Light Irradiation of a Photoresponsive Hydrogel Sheet2009

    • Author(s)
      須丸公雄・Szilagyi Andras・杉浦慎治・高木俊之・服部浩二・金森敏幸
    • Organizer
      第19回日本MRS学術シンポジウム
    • Place of Presentation
      横浜市
    • Year and Date
      2009-12-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] フォトクロミックハイドロゲルの光応答物性に及ぼすスピロピラン誘導体構造の影響2009

    • Author(s)
      佐藤琢, 須丸公雄, 高木俊之, 高井克毅, 金森敏幸
    • Organizer
      材料化学システム工学討論会2009
    • Place of Presentation
      東京都
    • Year and Date
      2009-12-07
    • Related Report
      2009 Annual Research Report
  • [Presentation] On-demand control of microfluidic system using photoresponsive hydrogel sheet2009

    • Author(s)
      Kimio Sumaru, Shinji Sugiura, Szilagyi Andras, Toshiyuki Takagi, Toshiyuki Kanamori
    • Organizer
      GelSympo2009
    • Place of Presentation
      Suita
    • Year and Date
      2009-12-04
    • Related Report
      2010 Final Research Report
  • [Presentation] Photo-response of pNIPAAm hydrogel functionalized with differently substituted spirobenzopyran derivatives2009

    • Author(s)
      Taku Satoh, Kimio Sumaru, Toshiyuki Takagi, Katsuki Takai, Toshiyuki Kanamori
    • Organizer
      GelSympo2009
    • Place of Presentation
      Suita
    • Year and Date
      2009-12-03
    • Related Report
      2010 Final Research Report
  • [Presentation] Photo-response of pNIPAAm hydrogel functionalized with differently substituted spirobenzopyran derivatives2009

    • Author(s)
      佐藤琢, 須丸公雄, 高木俊之, 高井克毅, 金森敏幸
    • Organizer
      GelSympo2009
    • Place of Presentation
      吹田市
    • Year and Date
      2009-12-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] On-demand control of microfluidic system using photoresponsive hydrogel sheet2009

    • Author(s)
      須丸公雄・杉浦慎治・Szilagyi Andras・高木俊之・金森敏幸
    • Organizer
      GelSympo2009
    • Place of Presentation
      吹田市
    • Year and Date
      2009-12-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] Photoresponsive Polymer Materials, Cell Bioassay Systems, Photochromism, Hydrogel, Microfluidics2009

    • Author(s)
      須丸公雄
    • Organizer
      ODRL Symposium~Functional Polymer and Its Application to Bioscience and Biotechnology~
    • Place of Presentation
      つくば市
    • Year and Date
      2009-11-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] スピロピラン修飾ハイドロゲルの光応答特性およびマイクロシステムのオンデマンド光制御への応用2009

    • Author(s)
      須丸公雄
    • Organizer
      高分子材料研究会
    • Place of Presentation
      東広島市(招待講演)
    • Year and Date
      2009-11-27
    • Related Report
      2010 Final Research Report
  • [Presentation] スピロピラン修飾ハイドロゲルの光応答特性およびマイクロシステムのオンデマンド光制御への応用2009

    • Author(s)
      須丸公雄
    • Organizer
      高分子材料研究会
    • Place of Presentation
      東広島市
    • Year and Date
      2009-11-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] フォトクロミックハイドロゲル膜の光応答収縮および再膨潤に対する担持スピロピラン構造の影響2009

    • Author(s)
      藤琢, 須丸公雄, 高木俊之, 高井克毅, 金森敏幸
    • Organizer
      膜シンポジウム
    • Place of Presentation
      東広島市
    • Year and Date
      2009-11-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 光応答ゲルシートを用いた集積型光制御マイクロ流体バルブ2009

    • Author(s)
      須丸公雄・Szilagyi Andras・杉浦慎治・高木俊之・服部浩二・金森敏幸
    • Organizer
      高分子討論会
    • Place of Presentation
      熊本市
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] スピロピラン修飾ポリマーの光応答ポリマーコンプレックス形成2009

    • Author(s)
      須丸公雄、高木俊之、高井克毅、金森敏幸
    • Organizer
      高分子討論会
    • Place of Presentation
      熊本市
    • Year and Date
      2009-09-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 光応答ゲルシートを用いた集積型光制御マイクロ流体バルブの構築2009

    • Author(s)
      須丸公雄, シラギーアンドラス, 杉浦慎治, 高木俊之, 服部浩二, 金森敏幸
    • Organizer
      日本膜学会第31年会
    • Place of Presentation
      東京都
    • Year and Date
      2009-05-21
    • Related Report
      2009 Annual Research Report
  • [Book] 光駆動ゲルアクチュエータ(未来を動かすソフトアクチュエータ-高分子・生体材料を中心とした研究開発-)2010

    • Author(s)
      須丸公雄, 高木俊之, 杉浦慎治, 金森敏幸
    • Publisher
      (株)シーエムシー出版
    • Related Report
      2010 Final Research Report
  • [Book] 光応答収縮ゲルによるバイオチップの光制御(食品・化粧品・医療分野へのゲルの利用)2010

    • Author(s)
      須丸公雄, 杉浦慎治, 高木俊之, 金森敏幸
    • Publisher
      (株)シーエムシー出版
    • Related Report
      2010 Final Research Report
  • [Book] 食品・化粧品・医療分野へのゲルの利用2010

    • Author(s)
      須丸公雄、杉浦慎治、高木俊之、金森敏幸
    • Total Pages
      5
    • Publisher
      シーエムシー出版
    • Related Report
      2010 Annual Research Report
  • [Book] 未来を動かすソフトアクチュエータ-高分子・生体材料を中心とした研究開発-2010

    • Author(s)
      須丸公雄、高木俊之、杉浦慎治、金森敏幸
    • Total Pages
      7
    • Publisher
      シーエムシー出版
    • Related Report
      2010 Annual Research Report
  • [Book] 光応答性ポリマー材料を用いたマイクロバイオチップの自在制御(ヘルスケアとバイオ医療のための先端デバイス機器)2009

    • Author(s)
      須丸公雄, 杉浦慎治, 金森敏幸
    • Publisher
      (株)シーエムシー出版
    • Related Report
      2010 Final Research Report
  • [Book] ヘルスケアとバイオ医療のための先端デバイス機器2009

    • Author(s)
      須丸公雄、杉浦慎治、金森敏幸
    • Total Pages
      13
    • Publisher
      シーエムシー出版
    • Related Report
      2009 Annual Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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