Detection of single receptor protein dynamics

• Project/Area Number: 20360014
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Applied materials science/Crystal engineering
• Research Institution: NTT Basic Research Laboratories
• Principal Investigator: TORIMITSU Keiichi NTT Basic Research Laboratories, 主席研究員 (00393728)
• Co-Investigator(Kenkyū-buntansha): SUMITOMO Koji NTT物性科学基礎研究所, 主幹研究員 (30393747) ; KASAI Nohoko NTT物性科学基礎研究所, 主任研究員 (50393749)
• Project Period (FY): 2008 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000); Fiscal Year 2010: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2009: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2008: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
• Keywords: バイオエレクトロニクス / 受容体タンパク質 / 脂質二分子膜 / 巨大ベシクル / 高速AFM / ナノホール / リガンド / マイクロドメイン / 金ナノロッド / 脂質マイクロドメイン

Research Abstract

In this research, we focused on a receptor protein to investigate the time dependent changes induced by a ligand binding experiment. Nanostructure changes were observed in real time using a fast scan AFM under physiological conditions. A nano-hole structure with a lipid receptor protein made it possible to analyze protein functions. This device architecture could be useful for a device with a biomimetic interface.

Research Products

• [Journal Article] Visualization of membrane protein suspended nanoscale well (2010)
  • Author(s): 篠崎陽一, 住友弘二, 古川一暁, H.Miyashita, Tamba, 河西奈保子, H. Nakashima, 鳥光慶一
  • Journal Title: Appl.Phys.Express 3
  • Peer Reviewed
• [Journal Article] Pattern formation and molecular transport of histidine-tagged GFPs using supported lipid bilayers (2010)
  • Author(s): H.Nakashima, 古川一暁, Y.Kashimura, 住友弘二, 篠崎陽一, 鳥光慶一
  • Journal Title: Langmur 26 Pages: 12716-12721
  • Peer Reviewed
• [Journal Article] Confinement of fluorescent probes in microwells on Si substrates by sealing with lipid bilayers (2010)
  • Author(s): 住友弘二, Y.Tambal, 篠崎陽一, 鳥光慶一
  • Journal Title: Appl.Phys.Express 3
  • NAID: 10027441637
  • Peer Reviewed
• [Journal Article] AFM observation of single, functioning ionotropic glutamate receptors reconstituted in lipid bilayers (2010)
  • Author(s): 河西奈保子, C.S.Ramanujan, I.Fujimoto, A.Shimada, J.F.Ryan, 鳥光慶一
  • Journal Title: BBA Gen.Sub. 1800 Pages: 655-661
  • Peer Reviewed
• [Journal Article] Pattern formation and molecular transport of histidine-tagged GFPs using supported lipid bilayers (2010)
  • Author(s): H.Nakashima, K.Furukawa, Y.Kashimura, K.Sumitomo, Y.Shinozaki K.Torimitsu
  • Journal Title: Langmur Volume: 26 Pages: 12716-12721
  • Peer Reviewed
• [Journal Article] Confinement of fluorescent probes in microwells on Si substrates by sealing with lipid bilayers (2010)
  • Author(s): K.Sumitomo, Y.Tamba, Y.Shinozaki, K.Torimitsu
  • Journal Title: Appl.Phys.Express Volume: 3
  • NAID: 10027441637
  • Peer Reviewed
• [Journal Article] AFM observation of single, functioning ionotropic glutamate receptors reconstituted in lipid bilayers (2010)
  • Author(s): N.Kasai, C.S.Ramanujan, I.Fujimoto, A.Shimada, J.F.Ryan, K.Torimitsu
  • Journal Title: BBA Gen.Sub. Volume: 1800 Pages: 655-661
  • Peer Reviewed
• [Journal Article] Visualization of membrane protein suspended over nanoscale well (2010)
  • Author(s): Y.Shinozaki, K.Sumitomo, K.Furukawa, H.Miyashita, Tamba, N.Kasai, H.Nakashima, K.Torimitsu
  • Journal Title: Appl.Phys.Express 3
  • Peer Reviewed
• [Journal Article] AFM observation of membrane proteins suspended over CNT network (2009)
  • Author(s): 住友弘二, 篠崎陽一, D.Takagi, H.Nakashima, 小林慶裕, 鳥光慶一
  • Journal Title: Jpn.J.Appl.Phys 48
  • Peer Reviewed
• [Journal Article] 高速原子間力顕微鏡を用いた受容体の一分子イメージング (2009)
  • Author(s): 篠崎陽一、住友弘二、津田誠、小泉修一、井上和秀、鳥光慶一
  • Journal Title: 日薬理誌(Folia Pharmacol. Jpn) 134 Pages: 68-72
  • NAID: 10025741229
  • Peer Reviewed
• [Journal Article] Direct obervation of ATP-induced conformational changes of single P2X4 receptor/channel (2009)
  • Author(s): 篠崎陽一, 住友弘二, 津田誠, 小泉修一, 井上和秀, 鳥光慶一
  • Journal Title: Plos Biol 7
  • Peer Reviewed
• [Journal Article] 受容体タンパク質の一分子観察 (2009)
  • Author(s): 河西奈保子、C.S.Ramanujan, 篠崎陽一、住友弘二、J.F.Ryan、鳥光慶一
  • Journal Title: 化学とマイクロンナノシステム 8 Pages: 1-6
  • NAID: 40016617273
• [Journal Article] Single molecular imaging of receptor proteins (2009)
  • Author(s): 河西奈保子, C.S.Ramanujan, 篠崎陽一, 住友弘二, J.F.Ryan, 鳥光慶一
  • Journal Title: J.Soc.Chem.Micro-Nano Sys. 8 Pages: 1-6
  • NAID: 40016617273
  • Peer Reviewed
• [Journal Article] Structural and Electrical Properties of Organic Conductive Polymers Bearing Tetrathiafulvalene Backbone (2009)
  • Author(s): Y.Kashimura, T.Goto, 古川一暁, E.Wang, H.Li, W.Hu, 鳥光慶一
  • Journal Title: Mol.Cryst.Liq.Cryst. 504 Pages: 231-237
  • Peer Reviewed
• [Journal Article] Neural signal transmission measurements with a conductive polymer microelectrode array (2009)
  • Author(s): A.Shimada, 河西奈保子, 古川一暁, T.Nyberg, 鳥光慶一
  • Journal Title: IEEJ Trans.EIS 129 Pages: 267-271
  • NAID: 10023999745
  • Peer Reviewed
• [Journal Article] Nanobio Research at NTT (2009)
  • Author(s): K.Toritmitsu
  • Journal Title: NTT Technical Review 7 Pages: 1-5
  • Peer Reviewed
• [Journal Article] Effect of Mg2+ on neural activity of rat cortical and hippocampal neurons in vitro (2009)
  • Author(s): 古川一暁, 河西奈保子, 鳥光慶一
  • Journal Title: Magnes.Res. 22
  • Peer Reviewed
• [Journal Article] AFM observation of membrane proteins suspended over CNT network (2009)
  • Author(s): 住友弘二, 篠崎陽一, D.Takagi, H.Nakashima, 小林慶裕, 鳥光慶一
  • Journal Title: Jpn.J.Appl.Phys. 48
  • Peer Reviewed
• [Journal Article] AFM observation of membrane proteins suspended over CNT network (2009)
  • Author(s): K.Sumitomo, Y.Shinozaki, D.Takagi, H.Nakashima, Y.Kobayashi, K.Torimitsu
  • Journal Title: Jpn.J.Appl.Phys. 48
  • Peer Reviewed
• [Journal Article] 高速原子間力顕微鏡を用いた受容体の一分子イメージング (2009)
  • Author(s): 篠崎陽一、住友弘二、津田誠、小泉修一、井上和秀、鳥光慶一
  • Journal Title: 日薬理誌(Folia Pharmacol. Jpn.) 134 Pages: 68-72
  • NAID: 10025741229
  • Peer Reviewed
• [Journal Article] Direct obervation of ATP-induced conformational changes of single P2X4 receptor/channel (2009)
  • Author(s): Y.Shinozaki, K.Sumitomo, M.Tsuda, S.Koizumi, K.Inoue, K.Torimitsu
  • Journal Title: PLoS Bio 1. 7
  • Peer Reviewed
• [Journal Article] Single molecular imaging of receptor proteins (2009)
  • Author(s): N.Kasai, C.S.Ramanujan, Y.Shinozaki, K.Sumitomo, J.F.Ryan
  • Journal Title: J.Soc.Chem.Micro-Nano Sys. 8 Pages: 1-6
  • NAID: 40016617273
  • Peer Reviewed
• [Journal Article] Structural and Electrical Properties of Organic Conductive Polymers Bearing Tetrathiafulvalene Backbone (2009)
  • Author(s): Y.Kashimura, T.Goto, K.Furukawa, E.Wang, H.Li, W.Hu, K.Torimitsu
  • Journal Title: Mol.Cryst.Liq.Cryst. 504 Pages: 231-237
  • Peer Reviewed
• [Journal Article] Neural signal transmission measurements with a conductive polymer microelectrode array (2009)
  • Author(s): A.Shimada, N.Kasai, Y.Furukawa, T.Nyberg, K.Torimitsu
  • Journal Title: IEEJ Trans.EIS 129 Pages: 267-271
  • NAID: 10023999745
  • Peer Reviewed
• [Journal Article] 受容体タンパク質の一分子観察 (2009)
  • Author(s): 河西奈保子、C, S. Ramanujan, 篠崎陽一、住友弘二、J. F. Ryan
  • Journal Title: 化学とマイクロナノシステム 8 Pages: 1-6
  • NAID: 40016617273
• [Journal Article] (2009)
  • Author(s): 鳥光慶一, 島田明佳, 古川由里子
  • Journal Title: 分子エレクトロニクスの基盤技術と将来展望(第4章 バイオ評価技術)(シーエムシー出版)
• [Journal Article] Elastic modulus of suspended purple membrane measured by atomic force microscopy applied surface science (2008)
  • Author(s): A.M.Siitonen, K.Sumitomo, C.S.Ramanujan, Y.Shinozaki, N.Kasai, K.Furukawa, J.F.Ryan, K. Torimitsu
  • Journal Title: Appl.Surf.Sci. 254 Pages: 7877-7800
  • Peer Reviewed
• [Journal Article] 単一分子レベルでのタンパク質の機能評価 (2008)
  • Author(s): 鳥光慶一、篠崎陽一、河西奈保子、住友弘二
  • Journal Title: 応用物理 77 Pages: 530-533
  • Peer Reviewed
• [Journal Article] Self-spreading Behavior of Supported Lipid Bilayer through Single sub-100-nm Gap (2008)
  • Author(s): Y.Kashimura, J.Durao, 古川一暁, 鳥光慶一
  • Journal Title: Jpn.J.Appl.Phys 47 Pages: 3248-3252
  • NAID: 10022550160
  • Peer Reviewed
• [Journal Article] Effect of Ca2+ on vesicle fusion on solid surface : An in vitro model of protein-accelerated vesicle fusion (2008)
  • Author(s): 篠崎陽一, A.M.Siitonen, 住友弘二, 古川一暁, 鳥光慶一
  • Journal Title: Jpn.J.Appl.Phys 47 Pages: 6164-6167
  • Peer Reviewed
• [Journal Article] Elastic modulus of suspended purple membrane measured by atomic force microscopy applied surface science (2008)
  • Author(s): A. M. Siitonen, K. Sumitomo, C. S. Ramanujan, Y. Shinozaki, N. Kasai, K, Furukawa. T. F. Ryan, K. Torimitsu
  • Journal Title: Appl. Surf. Sci. 254 Pages: 7877-7800
  • Peer Reviewed
• [Journal Article] Effect of Ca2+ on vesicle fusion on solid surface : An in vitro model of protein-accelerated vesicle fusion (2008)
  • Author(s): Y. Shinozaki, A. M. Siitonen, K. Sumitomo, K. Furukawa, K. Torimitsu
  • Journal Title: Jpn. J. Appl. Phys 47 Pages: 6164-6167
  • Peer Reviewed
• [Presentation] Fast scanning AFM of ionotropic receptors (2011)
  • Author(s): 鳥光慶一
  • Organizer: Biophysical Society 55^<th> Annual Meeting
  • Place of Presentation: Baltimore, USA
• [Presentation] Nanobiodevice architecture using receptor protein (2010)
  • Author(s): 鳥光慶一
  • Organizer: International Conference Nanoscience and Nanotechnology (ICONN 2010)
  • Place of Presentation: Sydney, Australia(Plenary talk)
• [Presentation] Understanding the Structure and Functions of Receptor Proteins (2010)
  • Author(s): 鳥光慶一, 篠崎陽一, 河西奈保子, A.Shimada, 住友弘二, C.Ramanujan, J.F.Ryan
  • Organizer: International Conference on Nanoscience and Nanotechnology (ICONN 2010)
  • Place of Presentation: Sydney, Australia(invited)
• [Presentation] Receptor Protein Based Nanobio-interface (2010)
  • Author(s): 鳥光慶一
  • Organizer: Asia-Pacific Symposium on Nanobionics
  • Place of Presentation: Wollongong, Australia
• [Presentation] Conformational nanostructure analysis of receptor protein and its application for biomimetic device formation (2010)
  • Author(s): 鳥光慶一, 篠崎陽一, Y.Furukawa, 河西奈保子, 住友弘二
  • Organizer: Gordon Research Conferences, Nanostructure Fabrication
  • Place of Presentation: Tilton, USA
• [Presentation] Functional analysis of receptor protein for biomimetic device formation -structure and function- (2010)
  • Author(s): 鳥光慶一
  • Organizer: 4th International Symposium Nanomedicine (ISNM2010)
  • Place of Presentation: Okazaki, Japan
• [Presentation] Functional analysis of receptor protein for biomimetic device formation -structure and function- (2010)
  • Author(s): 鳥光慶一
  • Organizer: The 4th Mt.Lofty workshop frontier technologies for systemfunctioonn and repair
  • Place of Presentation: Adelaide, Australia
• [Presentation] Receptor Protein Based Nanobio-interface (2010)
  • Author(s): K.Torimitsu
  • Organizer: Asia-Pacific Symposium on Nanobionics
  • Place of Presentation: Wollongong(Australia)
• [Presentation] Conformational nanostructure analysis of receptor protein and its application for biomimetic device formation (2010)
  • Author(s): K.Torimitsu, Y.Shinozaki, Y.Furukawa, N.Kasai, K.Sumitomo
  • Organizer: Gordon Research Conferences, Nanostructure Fabrication
  • Place of Presentation: Tilton(USA)
• [Presentation] Functional analysis of receptor protein for biomimetic device formation -structure and function- (2010)
  • Author(s): K.Torimitsu
  • Organizer: 4th International Symposium on Nanomedicine(ISNM2010)
  • Place of Presentation: Okazaki, Japan
• [Presentation] Functional analysis of receptor protein for biomimetic device formation-structure and function- (2010)
  • Author(s): K.Torimitsu
  • Organizer: The 4th Mt.Lofty workshop on frontier technologies for nervous system function and repair
  • Place of Presentation: Adelaide(Australia)
• [Presentation] Nanobiodevice architecture using receptor protein (2010)
  • Author(s): K.Torimitsu
  • Organizer: International Conference on Nanoscience and Nanotechnology(ICONN 2010)
  • Place of Presentation: Sydney, Australia
• [Presentation] Niキレート脂質を含む混合脂質膜のドメイン構造形成とGFPの位置選択的固定化 (2009)
  • Author(s): 中島寛、住友弘二、古川一暁、篠崎陽一、鳥光慶一
  • Organizer: 第62回コロイドおよび界面化学討論会
  • Place of Presentation: 岡山理科大学
  • Year and Date: 2009-06-15
• [Presentation] グリア細胞に発現するストレス応答に関わるATP受容体の解析 (2009)
  • Author(s): 篠崎陽一,住友弘二,小泉修一、津田誠、井上和秀、鳥光慶一
  • Organizer: 第13回神経科学領域における分子モニタリングシンポジウム
  • Place of Presentation: 愛知
  • Year and Date: 2009-01-10
• [Presentation] グリア細胞に発現するストレス応答に関わるATP受容体の解析 (2009)
  • Author(s): 篠崎陽一, 住友弘二, 小泉修一, 津田誠, 井上和秀, 鳥光慶一
  • Organizer: 第13回 神経科学領域における分子モニタリングシンポジウム
  • Place of Presentation: 愛知
  • Year and Date: 2009-01-10
• [Presentation] The preferential reconstitution of AMPA receptor proteins into model lipid domains incorporating cholesterol studied by atomic microscopy -an imaging and force spectroscopy study (2009)
  • Author(s): C.S.Ramanujan, 河西奈保子, M.Suggit, J.Baranovic, 鳥光慶一, J.F.Ryan
  • Organizer: Biophysical Society 53rd Annual Meeting
  • Place of Presentation: Boston, USA
• [Presentation] Molecular-scale detection of antigen-antibody reaction on 2D arrayed gold nanorods (2009)
  • Author(s): H.Nakashima, 古川一暁, 篠崎陽一, 住友弘二, 鳥光慶一
  • Organizer: 83^<rd> ACS Colloid and Surface Science Symposium
  • Place of Presentation: New York, USA
• [Presentation] Neural signal measurements with a conductive- polymer microelectrode array (2009)
  • Author(s): A.Shimada, 河西奈保子, 鳥光慶一
  • Organizer: XXXVI Int.Congress of Physiological Sciences, IUPS2009
  • Place of Presentation: Kyoto, Japan
• [Presentation] Structural observation of a single, reconstituted ionotropic glutamate receptor (2009)
  • Author(s): 河西奈保子, C.S.Ramanujan, J.Baranovic, 篠崎陽一, A.Shimada, 住友弘二, J.F.Ryan, 鳥光慶一
  • Organizer: XXXVI Int.Congress of Physiological Sciences, IUPS2009
  • Place of Presentation: Kyoto, Japan
• [Presentation] Dynamic structural changes in single P2X4 receptors observed with fast-scanning atomic force microscopy (2009)
  • Author(s): 篠崎陽一, 住友弘二, 津田誠, 小泉修一, K.Inoue, 鳥光慶一
  • Organizer: XXXVI Int.Congress of Physiological Sciences, IUPS2009
  • Place of Presentation: Kyoto, Japan
• [Presentation] Localization of P2X4 receptors in lipid raft-structure of an in vitro model of cell membrane (2009)
  • Author(s): 篠崎陽一, 住友弘二, 津田誠, 小泉修一, K.Inoue, 鳥光慶一
  • Organizer: Fukuoka Purine 2009
  • Place of Presentation: Fukuoka, Japan
• [Presentation] AMPA receptors in laterally heterogeneous lipid bilayers (2009)
  • Author(s): J.Baranovic, C.S.Ramanujan, N.Kasai, 篠崎陽一, 鳥光慶一, J.F.Ryan
  • Organizer: 39th annual meeting of the Society for Neuroscience, Neuroscience 2009
  • Place of Presentation: Chicago, USA
• [Presentation] Orientation of AMPA receptors reconstituted into artificial lipid bilayer (2009)
  • Author(s): 河西奈保子, T.Balois, C.S.Ramanujan, 篠崎陽一, 住友弘二, J.F.Ryan, 鳥光慶一
  • Organizer: 39th annual meeting of the Society for Neuroscience, Neuroscience 2009
  • Place of Presentation: Chicago, USA
• [Presentation] Understanding receptor protein structure and functions for biomimetic device (2009)
  • Author(s): 鳥光慶一
  • Organizer: ISNM2009-2
  • Place of Presentation: Okazaki, Japan (Special talk)
• [Presentation] Direct visualization of single receptor dynamics : the relationship between molecular structure and physiology/pathology (2009)
  • Author(s): 篠崎陽一, 住友弘二, 津田誠, 小泉修一, 井上和秀, 鳥光慶一
  • Organizer: ISNM2009-2
  • Place of Presentation: Okazaki, Japan
• [Presentation] Understanding receptor protein structure and functions for biomimetic device (2009)
  • Author(s): K.Torimitsu
  • Organizer: ISNM2009-2
  • Place of Presentation: Okazaki, Japan
• [Presentation] Neural signal measurements with a conductive-polymer microelectrode array (2009)
  • Author(s): A.Shimada, N.Kasai, K.Torimitsu
  • Organizer: XXXVI Int.Congress of Physiological Sciences, IUPS2009
  • Place of Presentation: Kyoto, Japan
• [Presentation] 単一分子レベルでの受容体タンパク質の機能観察 (2008)
  • Author(s): 住友弘二, 篠崎陽一, 河西奈保子, 鳥光慶一
  • Organizer: ナノプローブテクノロジー第167委員会第52回研究会
  • Place of Presentation: 東京
  • Year and Date: 2008-11-26
• [Presentation] 単一分子レベルでの受容体タンパク質の機能観察 (2008)
  • Author(s): 住友弘二, 篠崎陽一, 河西奈保子, 鳥光慶一
  • Organizer: ナノプローブテクノロジー第167委員会、第52回研究会
  • Place of Presentation: 東京
  • Year and Date: 2008-11-26
• [Presentation] Development of Nanobio Interface using Neurons and Receptor Proteins (2008)
  • Author(s): 鳥光慶一
  • Organizer: Asia-Pacific Symposium on Nanobionics
  • Place of Presentation: Wollongong, Australia
• [Presentation] Single receptor/channel imaging P2X4 receptor (2008)
  • Author(s): 篠崎陽一, 住友弘二, 津田誠, 小泉修一, 井上和秀, 鳥光慶一
  • Organizer: Purines 2008 Meeting
  • Place of Presentation: Copenhagen, Denmark
• [Presentation] Ionotropic glutamate receptors in artificial membranes (2008)
  • Author(s): J.Baranovic, C.S.Ramanujan, N.Kasai, 鳥光慶一, J.F.Ryan
  • Organizer: Young Physiologists Symposium 2008
  • Place of Presentation: Cambridge, UK
• [Presentation] CNTネットワーク上での膜タンパク質のAFM観察 (2008)
  • Author(s): 住友弘二, 篠崎陽一, 高木大輔, 中島寛, 小林慶裕, 鳥光慶一
  • Organizer: 第69回応用物理学会講演会
  • Place of Presentation: 中部大学、愛知
• [Presentation] P2X4受容体のポア開閉及びポア拡大に関連する構造変化の観察 (2008)
  • Author(s): 篠崎陽一、住友弘二、津田誠、小泉修一、井上和秀、鳥光慶一
  • Organizer: 第13回ATP・アデノシン研究会
  • Place of Presentation: 愛知
• [Presentation] 原子間力顕微鏡を用いたNMDA受容体の一分子観察 (2008)
  • Author(s): 篠崎陽一, 住友弘二, 鳥光慶一
  • Organizer: 第51回日本神経化学会大会
  • Place of Presentation: 富山
• [Presentation] AFM imaging of pore opening/dilation-related structural changes in P2X4 receptors (2008)
  • Author(s): 篠崎陽一, K.Sumitomo, 鳥光慶一
  • Organizer: Workshop of the UK-Japan Bionanotechnology Collaboration
  • Place of Presentation: Kobe, Japan
• [Presentation] AFM observation of membrane proteins suspended over nanowells : structure and functional analysis (2008)
  • Author(s): 住友弘二, 篠崎陽一, 河西奈保子, H.Nakashima, A.M.Siitonen, 鳥光慶一, C.S.Ramanujan, J.F.Ryan
  • Organizer: Workshop of the UK-Japan Bionanotechnology Collaboration
  • Place of Presentation: Kobe, Japan
• [Presentation] Reconstitution of AMPA receptors into lipid mixtures incorporating cholesterol (2008)
  • Author(s): C.S.Ramanujan, 河西奈保子, K.Marwaha, M.Suggit, 鳥光慶一, J.F.Ryan
  • Organizer: Workshop of the UK-Japan Bionanotechnology Collaboration
  • Place of Presentation: Kobe, Japan
• [Presentation] Structural change of an ionotropic glutamate receptor reconstituted into lipid bilayer (2008)
  • Author(s): 河西奈保子, C.S.Ramanujan, J.Baranovic, 篠崎陽一, A.Shimada, 住友弘二, J.F.Ryan, 鳥光慶一
  • Organizer: 38^<th> annual meeting of the Society for Neuroscience. Neuroscience 2008
  • Place of Presentation: Washington, DC
• [Presentation] Nanobio-application in medical bionics (2008)
  • Author(s): 鳥光慶一
  • Organizer: The Sir Mark Oliphant International Frontier of Science and Technology Conference Series -Medical bionics-
  • Place of Presentation: Lorne, Australia (invited)
• [Presentation] Receptor protein functions and its application for biomimetic device (2008)
  • Author(s): 鳥光慶一
  • Organizer: The 5th Sweden-Japan Workshop on Bio-Nanotechnology
  • Place of Presentation: Stockholm, Sweden (invited)
• [Presentation] AFM observation of membrane proteins suspended over CNT network (2008)
  • Author(s): 住友弘二, 篠崎陽一, D.Takagi, H.Nakashima, 小林慶裕, 鳥光慶一
  • Organizer: 16th International Colloquium on Scanning Probe Microscopy, ICSPM-16
  • Place of Presentation: Atagawa, Japan
• [Presentation] Protein-based nanobio research for medical bionics (2008)
  • Author(s): K.Torimtisu
  • Organizer: Symposium on Advanced Fluid Information and Transdisciplinary Fluid Integration
  • Place of Presentation: Sendai, Japan(invited)
• [Presentation] Protein-based nanobio research for medical bionics (2008)
  • Author(s): K. Torimtisu
  • Organizer: Symposium on Advanced Fluid Information and Transdisciplinary Fluid Integration
  • Place of Presentation: Sendai, Japan
• [Presentation] Receptor protein functions and its application for biomimetic device (2008)
  • Author(s): K. Torimitsu
  • Organizer: The 5th Sweden-Japan Workshop on Bio-Nanotechnology
  • Place of Presentation: Stockholm, Sweden
• [Presentation] Nanobio-application in medical bionics (2008)
  • Author(s): K. Torimitsu
  • Organizer: The Sir Mark Oliphant International Frontier of Science and Technology Conference Series-Medical bionics-
  • Place of Presentation: Lorne, Australia
• [Presentation] Structural change of an ionotropic glutamate receptor reconstituted into lipid bilayer (2008)
  • Author(s): N. Kasai, C. S. Ramanujan, J. Baranovic, Y. Shinozaki, A, Shimada, K. Sumitomo. I. F. Ryan, K. Torimitsu
  • Organizer: 38th annual meeting of the Society for Neuroscience, Neuroscience 2008
  • Place of Presentation: Washington, DC
• [Presentation] AFM Observation of membrane proteins suspended over nanowells : structure and functional analysis (2008)
  • Author(s): K. Sumitomo, Y. Shinozaki, N. Kasai, H. Nakashima, A. M. Siitonen, K. Torimitsu. C. S. Ramanujan. J. F. Ryan
  • Organizer: Workshop of the UK-Japan Bionanotechnology Collaboration
  • Place of Presentation: Kobe, Japan
• [Book] 分子エレクトロニクスの基盤技術と将来展望(第4章バイオ評価技術) (2009)
  • Author(s): 鳥光慶一、島田明佳、古川由里子
  • Total Pages: 14
  • Publisher: シーエムシー出版
• [Patent(Industrial Property Rights)] 脂質二分子膜基板 (2010)
  • Inventor(s): 住友弘二、篠崎陽一、中島寛、島田明佳、河西奈保子、鳥光慶一
  • Industrial Property Rights Holder: 日本電信電話株式会社
  • Industrial Property Number: 2010-026703
  • Filing Date: 2010-02-09
• [Patent(Industrial Property Rights)] 膜タンパク質機能測定システムおよび膜タンパク質機能測定方法 (2009)
  • Inventor(s): 篠崎陽一、住友弘二、河西奈保子、中島寛、鳥光慶一
  • Industrial Property Rights Holder: 日本電信電話株式会社
  • Industrial Property Number: 2009-169079
  • Filing Date: 2009-07-17
• [Patent(Industrial Property Rights)] 膜タンパク質機能測定基板および 膜タンパク質機能測定方法 (2008)
  • Inventor(s): 篠崎陽一、住友弘二、中島寛、河西奈保子、鳥光慶一
  • Industrial Property Rights Holder: 日本電信電話株式会社
  • Industrial Property Number: 2008-296830
  • Filing Date: 2008-11-20
• [Patent(Industrial Property Rights)] 膜タンパク質の脂質膜内配向評価方法 (2008)
  • Inventor(s): 河西奈保子、篠崎陽一、住友弘二、鳥光慶一
  • Industrial Property Rights Holder: 日本電信電話株式会社
  • Industrial Property Number: 2008-031994
  • Filing Date: 2008-12-16