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Detection of single receptor protein dynamics

Research Project

Project/Area Number 20360014
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied materials science/Crystal engineering
Research InstitutionNTT Basic Research Laboratories

Principal Investigator

TORIMITSU Keiichi  NTT Basic Research Laboratories, 主席研究員 (00393728)

Co-Investigator(Kenkyū-buntansha) SUMITOMO Koji  NTT物性科学基礎研究所, 主幹研究員 (30393747)
KASAI Nohoko  NTT物性科学基礎研究所, 主任研究員 (50393749)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000)
Fiscal Year 2010: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2009: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2008: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Keywordsバイオエレクトロニクス / 受容体タンパク質 / 脂質二分子膜 / 巨大ベシクル / 高速AFM / ナノホール / リガンド / マイクロドメイン / 金ナノロッド / 脂質マイクロドメイン
Research Abstract

In this research, we focused on a receptor protein to investigate the time dependent changes induced by a ligand binding experiment. Nanostructure changes were observed in real time using a fast scan AFM under physiological conditions. A nano-hole structure with a lipid receptor protein made it possible to analyze protein functions. This device architecture could be useful for a device with a biomimetic interface.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (85 results)

All 2011 2010 2009 2008

All Journal Article (32 results) (of which Peer Reviewed: 29 results) Presentation (48 results) Book (1 results) Patent(Industrial Property Rights) (4 results)

  • [Journal Article] Visualization of membrane protein suspended nanoscale well2010

    • Author(s)
      篠崎陽一, 住友弘二, 古川一暁, H.Miyashita, Tamba, 河西奈保子, H. Nakashima, 鳥光慶一
    • Journal Title

      Appl.Phys.Express 3

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pattern formation and molecular transport of histidine-tagged GFPs using supported lipid bilayers2010

    • Author(s)
      H.Nakashima, 古川一暁, Y.Kashimura, 住友弘二, 篠崎陽一, 鳥光慶一
    • Journal Title

      Langmur 26

      Pages: 12716-12721

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Confinement of fluorescent probes in microwells on Si substrates by sealing with lipid bilayers2010

    • Author(s)
      住友弘二, Y.Tambal, 篠崎陽一, 鳥光慶一
    • Journal Title

      Appl.Phys.Express 3

    • NAID

      10027441637

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] AFM observation of single, functioning ionotropic glutamate receptors reconstituted in lipid bilayers2010

    • Author(s)
      河西奈保子, C.S.Ramanujan, I.Fujimoto, A.Shimada, J.F.Ryan, 鳥光慶一
    • Journal Title

      BBA Gen.Sub. 1800

      Pages: 655-661

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Pattern formation and molecular transport of histidine-tagged GFPs using supported lipid bilayers2010

    • Author(s)
      H.Nakashima, K.Furukawa, Y.Kashimura, K.Sumitomo, Y.Shinozaki K.Torimitsu
    • Journal Title

      Langmur

      Volume: 26 Pages: 12716-12721

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Confinement of fluorescent probes in microwells on Si substrates by sealing with lipid bilayers2010

    • Author(s)
      K.Sumitomo, Y.Tamba, Y.Shinozaki, K.Torimitsu
    • Journal Title

      Appl.Phys.Express

      Volume: 3

    • NAID

      10027441637

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] AFM observation of single, functioning ionotropic glutamate receptors reconstituted in lipid bilayers2010

    • Author(s)
      N.Kasai, C.S.Ramanujan, I.Fujimoto, A.Shimada, J.F.Ryan, K.Torimitsu
    • Journal Title

      BBA Gen.Sub.

      Volume: 1800 Pages: 655-661

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visualization of membrane protein suspended over nanoscale well2010

    • Author(s)
      Y.Shinozaki, K.Sumitomo, K.Furukawa, H.Miyashita, Tamba, N.Kasai, H.Nakashima, K.Torimitsu
    • Journal Title

      Appl.Phys.Express 3

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] AFM observation of membrane proteins suspended over CNT network2009

    • Author(s)
      住友弘二, 篠崎陽一, D.Takagi, H.Nakashima, 小林慶裕, 鳥光慶一
    • Journal Title

      Jpn.J.Appl.Phys 48

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 高速原子間力顕微鏡を用いた受容体の一分子イメージング2009

    • Author(s)
      篠崎陽一、住友弘二、津田誠、小泉修一、井上和秀、鳥光慶一
    • Journal Title

      日薬理誌(Folia Pharmacol. Jpn) 134

      Pages: 68-72

    • NAID

      10025741229

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Direct obervation of ATP-induced conformational changes of single P2X4 receptor/channel2009

    • Author(s)
      篠崎陽一, 住友弘二, 津田誠, 小泉修一, 井上和秀, 鳥光慶一
    • Journal Title

      Plos Biol 7

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 受容体タンパク質の一分子観察2009

    • Author(s)
      河西奈保子、C.S.Ramanujan, 篠崎陽一、住友弘二、J.F.Ryan、鳥光慶一
    • Journal Title

      化学とマイクロンナノシステム 8

      Pages: 1-6

    • NAID

      40016617273

    • Related Report
      2010 Final Research Report
  • [Journal Article] Single molecular imaging of receptor proteins2009

    • Author(s)
      河西奈保子, C.S.Ramanujan, 篠崎陽一, 住友弘二, J.F.Ryan, 鳥光慶一
    • Journal Title

      J.Soc.Chem.Micro-Nano Sys. 8

      Pages: 1-6

    • NAID

      40016617273

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structural and Electrical Properties of Organic Conductive Polymers Bearing Tetrathiafulvalene Backbone2009

    • Author(s)
      Y.Kashimura, T.Goto, 古川一暁, E.Wang, H.Li, W.Hu, 鳥光慶一
    • Journal Title

      Mol.Cryst.Liq.Cryst. 504

      Pages: 231-237

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural signal transmission measurements with a conductive polymer microelectrode array2009

    • Author(s)
      A.Shimada, 河西奈保子, 古川一暁, T.Nyberg, 鳥光慶一
    • Journal Title

      IEEJ Trans.EIS 129

      Pages: 267-271

    • NAID

      10023999745

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Nanobio Research at NTT2009

    • Author(s)
      K.Toritmitsu
    • Journal Title

      NTT Technical Review 7

      Pages: 1-5

    • Related Report
      2010 Final Research Report 2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Mg2+ on neural activity of rat cortical and hippocampal neurons in vitro2009

    • Author(s)
      古川一暁, 河西奈保子, 鳥光慶一
    • Journal Title

      Magnes.Res. 22

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] AFM observation of membrane proteins suspended over CNT network2009

    • Author(s)
      住友弘二, 篠崎陽一, D.Takagi, H.Nakashima, 小林慶裕, 鳥光慶一
    • Journal Title

      Jpn.J.Appl.Phys. 48

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] AFM observation of membrane proteins suspended over CNT network2009

    • Author(s)
      K.Sumitomo, Y.Shinozaki, D.Takagi, H.Nakashima, Y.Kobayashi, K.Torimitsu
    • Journal Title

      Jpn.J.Appl.Phys. 48

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 高速原子間力顕微鏡を用いた受容体の一分子イメージング2009

    • Author(s)
      篠崎陽一、住友弘二、津田誠、小泉修一、井上和秀、鳥光慶一
    • Journal Title

      日薬理誌(Folia Pharmacol. Jpn.) 134

      Pages: 68-72

    • NAID

      10025741229

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct obervation of ATP-induced conformational changes of single P2X4 receptor/channel2009

    • Author(s)
      Y.Shinozaki, K.Sumitomo, M.Tsuda, S.Koizumi, K.Inoue, K.Torimitsu
    • Journal Title

      PLoS Bio 1. 7

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Single molecular imaging of receptor proteins2009

    • Author(s)
      N.Kasai, C.S.Ramanujan, Y.Shinozaki, K.Sumitomo, J.F.Ryan
    • Journal Title

      J.Soc.Chem.Micro-Nano Sys. 8

      Pages: 1-6

    • NAID

      40016617273

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural and Electrical Properties of Organic Conductive Polymers Bearing Tetrathiafulvalene Backbone2009

    • Author(s)
      Y.Kashimura, T.Goto, K.Furukawa, E.Wang, H.Li, W.Hu, K.Torimitsu
    • Journal Title

      Mol.Cryst.Liq.Cryst. 504

      Pages: 231-237

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Neural signal transmission measurements with a conductive polymer microelectrode array2009

    • Author(s)
      A.Shimada, N.Kasai, Y.Furukawa, T.Nyberg, K.Torimitsu
    • Journal Title

      IEEJ Trans.EIS 129

      Pages: 267-271

    • NAID

      10023999745

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 受容体タンパク質の一分子観察2009

    • Author(s)
      河西奈保子、C, S. Ramanujan, 篠崎陽一、住友弘二、J. F. Ryan
    • Journal Title

      化学とマイクロナノシステム 8

      Pages: 1-6

    • NAID

      40016617273

    • Related Report
      2008 Annual Research Report
  • [Journal Article]2009

    • Author(s)
      鳥光慶一, 島田明佳, 古川由里子
    • Journal Title

      分子エレクトロニクスの基盤技術と将来展望(第4章 バイオ評価技術)(シーエムシー出版)

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Elastic modulus of suspended purple membrane measured by atomic force microscopy applied surface science2008

    • Author(s)
      A.M.Siitonen, K.Sumitomo, C.S.Ramanujan, Y.Shinozaki, N.Kasai, K.Furukawa, J.F.Ryan, K. Torimitsu
    • Journal Title

      Appl.Surf.Sci. 254

      Pages: 7877-7800

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 単一分子レベルでのタンパク質の機能評価2008

    • Author(s)
      鳥光慶一、篠崎陽一、河西奈保子、住友弘二
    • Journal Title

      応用物理 77

      Pages: 530-533

    • Related Report
      2010 Final Research Report 2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-spreading Behavior of Supported Lipid Bilayer through Single sub-100-nm Gap2008

    • Author(s)
      Y.Kashimura, J.Durao, 古川一暁, 鳥光慶一
    • Journal Title

      Jpn.J.Appl.Phys 47

      Pages: 3248-3252

    • NAID

      10022550160

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Ca2+ on vesicle fusion on solid surface : An in vitro model of protein-accelerated vesicle fusion2008

    • Author(s)
      篠崎陽一, A.M.Siitonen, 住友弘二, 古川一暁, 鳥光慶一
    • Journal Title

      Jpn.J.Appl.Phys 47

      Pages: 6164-6167

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Elastic modulus of suspended purple membrane measured by atomic force microscopy applied surface science2008

    • Author(s)
      A. M. Siitonen, K. Sumitomo, C. S. Ramanujan, Y. Shinozaki, N. Kasai, K, Furukawa. T. F. Ryan, K. Torimitsu
    • Journal Title

      Appl. Surf. Sci. 254

      Pages: 7877-7800

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of Ca2+ on vesicle fusion on solid surface : An in vitro model of protein-accelerated vesicle fusion2008

    • Author(s)
      Y. Shinozaki, A. M. Siitonen, K. Sumitomo, K. Furukawa, K. Torimitsu
    • Journal Title

      Jpn. J. Appl. Phys 47

      Pages: 6164-6167

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Fast scanning AFM of ionotropic receptors2011

    • Author(s)
      鳥光慶一
    • Organizer
      Biophysical Society 55^<th> Annual Meeting
    • Place of Presentation
      Baltimore, USA
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Nanobiodevice architecture using receptor protein2010

    • Author(s)
      鳥光慶一
    • Organizer
      International Conference Nanoscience and Nanotechnology (ICONN 2010)
    • Place of Presentation
      Sydney, Australia(Plenary talk)
    • Related Report
      2010 Final Research Report
  • [Presentation] Understanding the Structure and Functions of Receptor Proteins2010

    • Author(s)
      鳥光慶一, 篠崎陽一, 河西奈保子, A.Shimada, 住友弘二, C.Ramanujan, J.F.Ryan
    • Organizer
      International Conference on Nanoscience and Nanotechnology (ICONN 2010)
    • Place of Presentation
      Sydney, Australia(invited)
    • Related Report
      2010 Final Research Report
  • [Presentation] Receptor Protein Based Nanobio-interface2010

    • Author(s)
      鳥光慶一
    • Organizer
      Asia-Pacific Symposium on Nanobionics
    • Place of Presentation
      Wollongong, Australia
    • Related Report
      2010 Final Research Report
  • [Presentation] Conformational nanostructure analysis of receptor protein and its application for biomimetic device formation2010

    • Author(s)
      鳥光慶一, 篠崎陽一, Y.Furukawa, 河西奈保子, 住友弘二
    • Organizer
      Gordon Research Conferences, Nanostructure Fabrication
    • Place of Presentation
      Tilton, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Functional analysis of receptor protein for biomimetic device formation -structure and function-2010

    • Author(s)
      鳥光慶一
    • Organizer
      4th International Symposium Nanomedicine (ISNM2010)
    • Place of Presentation
      Okazaki, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Functional analysis of receptor protein for biomimetic device formation -structure and function-2010

    • Author(s)
      鳥光慶一
    • Organizer
      The 4th Mt.Lofty workshop frontier technologies for systemfunctioonn and repair
    • Place of Presentation
      Adelaide, Australia
    • Related Report
      2010 Final Research Report
  • [Presentation] Receptor Protein Based Nanobio-interface2010

    • Author(s)
      K.Torimitsu
    • Organizer
      Asia-Pacific Symposium on Nanobionics
    • Place of Presentation
      Wollongong(Australia)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Conformational nanostructure analysis of receptor protein and its application for biomimetic device formation2010

    • Author(s)
      K.Torimitsu, Y.Shinozaki, Y.Furukawa, N.Kasai, K.Sumitomo
    • Organizer
      Gordon Research Conferences, Nanostructure Fabrication
    • Place of Presentation
      Tilton(USA)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Functional analysis of receptor protein for biomimetic device formation -structure and function-2010

    • Author(s)
      K.Torimitsu
    • Organizer
      4th International Symposium on Nanomedicine(ISNM2010)
    • Place of Presentation
      Okazaki, Japan
    • Related Report
      2010 Annual Research Report
  • [Presentation] Functional analysis of receptor protein for biomimetic device formation-structure and function-2010

    • Author(s)
      K.Torimitsu
    • Organizer
      The 4th Mt.Lofty workshop on frontier technologies for nervous system function and repair
    • Place of Presentation
      Adelaide(Australia)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Nanobiodevice architecture using receptor protein2010

    • Author(s)
      K.Torimitsu
    • Organizer
      International Conference on Nanoscience and Nanotechnology(ICONN 2010)
    • Place of Presentation
      Sydney, Australia
    • Related Report
      2009 Annual Research Report
  • [Presentation] Niキレート脂質を含む混合脂質膜のドメイン構造形成とGFPの位置選択的固定化2009

    • Author(s)
      中島寛、住友弘二、古川一暁、篠崎陽一、鳥光慶一
    • Organizer
      第62回コロイドおよび界面化学討論会
    • Place of Presentation
      岡山理科大学
    • Year and Date
      2009-06-15
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] グリア細胞に発現するストレス応答に関わるATP受容体の解析2009

    • Author(s)
      篠崎陽一,住友弘二,小泉修一、津田誠、井上和秀、鳥光慶一
    • Organizer
      第13回神経科学領域における分子モニタリングシンポジウム
    • Place of Presentation
      愛知
    • Year and Date
      2009-01-10
    • Related Report
      2010 Final Research Report
  • [Presentation] グリア細胞に発現するストレス応答に関わるATP受容体の解析2009

    • Author(s)
      篠崎陽一, 住友弘二, 小泉修一, 津田誠, 井上和秀, 鳥光慶一
    • Organizer
      第13回 神経科学領域における分子モニタリングシンポジウム
    • Place of Presentation
      愛知
    • Year and Date
      2009-01-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] The preferential reconstitution of AMPA receptor proteins into model lipid domains incorporating cholesterol studied by atomic microscopy -an imaging and force spectroscopy study2009

    • Author(s)
      C.S.Ramanujan, 河西奈保子, M.Suggit, J.Baranovic, 鳥光慶一, J.F.Ryan
    • Organizer
      Biophysical Society 53rd Annual Meeting
    • Place of Presentation
      Boston, USA
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] Molecular-scale detection of antigen-antibody reaction on 2D arrayed gold nanorods2009

    • Author(s)
      H.Nakashima, 古川一暁, 篠崎陽一, 住友弘二, 鳥光慶一
    • Organizer
      83^<rd> ACS Colloid and Surface Science Symposium
    • Place of Presentation
      New York, USA
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Neural signal measurements with a conductive- polymer microelectrode array2009

    • Author(s)
      A.Shimada, 河西奈保子, 鳥光慶一
    • Organizer
      XXXVI Int.Congress of Physiological Sciences, IUPS2009
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Structural observation of a single, reconstituted ionotropic glutamate receptor2009

    • Author(s)
      河西奈保子, C.S.Ramanujan, J.Baranovic, 篠崎陽一, A.Shimada, 住友弘二, J.F.Ryan, 鳥光慶一
    • Organizer
      XXXVI Int.Congress of Physiological Sciences, IUPS2009
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Dynamic structural changes in single P2X4 receptors observed with fast-scanning atomic force microscopy2009

    • Author(s)
      篠崎陽一, 住友弘二, 津田誠, 小泉修一, K.Inoue, 鳥光慶一
    • Organizer
      XXXVI Int.Congress of Physiological Sciences, IUPS2009
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Localization of P2X4 receptors in lipid raft-structure of an in vitro model of cell membrane2009

    • Author(s)
      篠崎陽一, 住友弘二, 津田誠, 小泉修一, K.Inoue, 鳥光慶一
    • Organizer
      Fukuoka Purine 2009
    • Place of Presentation
      Fukuoka, Japan
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] AMPA receptors in laterally heterogeneous lipid bilayers2009

    • Author(s)
      J.Baranovic, C.S.Ramanujan, N.Kasai, 篠崎陽一, 鳥光慶一, J.F.Ryan
    • Organizer
      39th annual meeting of the Society for Neuroscience, Neuroscience 2009
    • Place of Presentation
      Chicago, USA
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Orientation of AMPA receptors reconstituted into artificial lipid bilayer2009

    • Author(s)
      河西奈保子, T.Balois, C.S.Ramanujan, 篠崎陽一, 住友弘二, J.F.Ryan, 鳥光慶一
    • Organizer
      39th annual meeting of the Society for Neuroscience, Neuroscience 2009
    • Place of Presentation
      Chicago, USA
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Understanding receptor protein structure and functions for biomimetic device2009

    • Author(s)
      鳥光慶一
    • Organizer
      ISNM2009-2
    • Place of Presentation
      Okazaki, Japan (Special talk)
    • Related Report
      2010 Final Research Report
  • [Presentation] Direct visualization of single receptor dynamics : the relationship between molecular structure and physiology/pathology2009

    • Author(s)
      篠崎陽一, 住友弘二, 津田誠, 小泉修一, 井上和秀, 鳥光慶一
    • Organizer
      ISNM2009-2
    • Place of Presentation
      Okazaki, Japan
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Understanding receptor protein structure and functions for biomimetic device2009

    • Author(s)
      K.Torimitsu
    • Organizer
      ISNM2009-2
    • Place of Presentation
      Okazaki, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] Neural signal measurements with a conductive-polymer microelectrode array2009

    • Author(s)
      A.Shimada, N.Kasai, K.Torimitsu
    • Organizer
      XXXVI Int.Congress of Physiological Sciences, IUPS2009
    • Place of Presentation
      Kyoto, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] 単一分子レベルでの受容体タンパク質の機能観察2008

    • Author(s)
      住友弘二, 篠崎陽一, 河西奈保子, 鳥光慶一
    • Organizer
      ナノプローブテクノロジー第167委員会第52回研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-26
    • Related Report
      2010 Final Research Report
  • [Presentation] 単一分子レベルでの受容体タンパク質の機能観察2008

    • Author(s)
      住友弘二, 篠崎陽一, 河西奈保子, 鳥光慶一
    • Organizer
      ナノプローブテクノロジー第167委員会、第52回研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-11-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Development of Nanobio Interface using Neurons and Receptor Proteins2008

    • Author(s)
      鳥光慶一
    • Organizer
      Asia-Pacific Symposium on Nanobionics
    • Place of Presentation
      Wollongong, Australia
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] Single receptor/channel imaging P2X4 receptor2008

    • Author(s)
      篠崎陽一, 住友弘二, 津田誠, 小泉修一, 井上和秀, 鳥光慶一
    • Organizer
      Purines 2008 Meeting
    • Place of Presentation
      Copenhagen, Denmark
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] Ionotropic glutamate receptors in artificial membranes2008

    • Author(s)
      J.Baranovic, C.S.Ramanujan, N.Kasai, 鳥光慶一, J.F.Ryan
    • Organizer
      Young Physiologists Symposium 2008
    • Place of Presentation
      Cambridge, UK
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] CNTネットワーク上での膜タンパク質のAFM観察2008

    • Author(s)
      住友弘二, 篠崎陽一, 高木大輔, 中島寛, 小林慶裕, 鳥光慶一
    • Organizer
      第69回応用物理学会講演会
    • Place of Presentation
      中部大学、愛知
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] P2X4受容体のポア開閉及びポア拡大に関連する構造変化の観察2008

    • Author(s)
      篠崎陽一、住友弘二、津田誠、小泉修一、井上和秀、鳥光慶一
    • Organizer
      第13回ATP・アデノシン研究会
    • Place of Presentation
      愛知
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] 原子間力顕微鏡を用いたNMDA受容体の一分子観察2008

    • Author(s)
      篠崎陽一, 住友弘二, 鳥光慶一
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] AFM imaging of pore opening/dilation-related structural changes in P2X4 receptors2008

    • Author(s)
      篠崎陽一, K.Sumitomo, 鳥光慶一
    • Organizer
      Workshop of the UK-Japan Bionanotechnology Collaboration
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] AFM observation of membrane proteins suspended over nanowells : structure and functional analysis2008

    • Author(s)
      住友弘二, 篠崎陽一, 河西奈保子, H.Nakashima, A.M.Siitonen, 鳥光慶一, C.S.Ramanujan, J.F.Ryan
    • Organizer
      Workshop of the UK-Japan Bionanotechnology Collaboration
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2010 Final Research Report
  • [Presentation] Reconstitution of AMPA receptors into lipid mixtures incorporating cholesterol2008

    • Author(s)
      C.S.Ramanujan, 河西奈保子, K.Marwaha, M.Suggit, 鳥光慶一, J.F.Ryan
    • Organizer
      Workshop of the UK-Japan Bionanotechnology Collaboration
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] Structural change of an ionotropic glutamate receptor reconstituted into lipid bilayer2008

    • Author(s)
      河西奈保子, C.S.Ramanujan, J.Baranovic, 篠崎陽一, A.Shimada, 住友弘二, J.F.Ryan, 鳥光慶一
    • Organizer
      38^<th> annual meeting of the Society for Neuroscience. Neuroscience 2008
    • Place of Presentation
      Washington, DC
    • Related Report
      2010 Final Research Report
  • [Presentation] Nanobio-application in medical bionics2008

    • Author(s)
      鳥光慶一
    • Organizer
      The Sir Mark Oliphant International Frontier of Science and Technology Conference Series -Medical bionics-
    • Place of Presentation
      Lorne, Australia (invited)
    • Related Report
      2010 Final Research Report
  • [Presentation] Receptor protein functions and its application for biomimetic device2008

    • Author(s)
      鳥光慶一
    • Organizer
      The 5th Sweden-Japan Workshop on Bio-Nanotechnology
    • Place of Presentation
      Stockholm, Sweden (invited)
    • Related Report
      2010 Final Research Report
  • [Presentation] AFM observation of membrane proteins suspended over CNT network2008

    • Author(s)
      住友弘二, 篠崎陽一, D.Takagi, H.Nakashima, 小林慶裕, 鳥光慶一
    • Organizer
      16th International Colloquium on Scanning Probe Microscopy, ICSPM-16
    • Place of Presentation
      Atagawa, Japan
    • Related Report
      2010 Final Research Report 2008 Annual Research Report
  • [Presentation] Protein-based nanobio research for medical bionics2008

    • Author(s)
      K.Torimtisu
    • Organizer
      Symposium on Advanced Fluid Information and Transdisciplinary Fluid Integration
    • Place of Presentation
      Sendai, Japan(invited)
    • Related Report
      2010 Final Research Report
  • [Presentation] Protein-based nanobio research for medical bionics2008

    • Author(s)
      K. Torimtisu
    • Organizer
      Symposium on Advanced Fluid Information and Transdisciplinary Fluid Integration
    • Place of Presentation
      Sendai, Japan
    • Related Report
      2008 Annual Research Report
  • [Presentation] Receptor protein functions and its application for biomimetic device2008

    • Author(s)
      K. Torimitsu
    • Organizer
      The 5th Sweden-Japan Workshop on Bio-Nanotechnology
    • Place of Presentation
      Stockholm, Sweden
    • Related Report
      2008 Annual Research Report
  • [Presentation] Nanobio-application in medical bionics2008

    • Author(s)
      K. Torimitsu
    • Organizer
      The Sir Mark Oliphant International Frontier of Science and Technology Conference Series-Medical bionics-
    • Place of Presentation
      Lorne, Australia
    • Related Report
      2008 Annual Research Report
  • [Presentation] Structural change of an ionotropic glutamate receptor reconstituted into lipid bilayer2008

    • Author(s)
      N. Kasai, C. S. Ramanujan, J. Baranovic, Y. Shinozaki, A, Shimada, K. Sumitomo. I. F. Ryan, K. Torimitsu
    • Organizer
      38th annual meeting of the Society for Neuroscience, Neuroscience 2008
    • Place of Presentation
      Washington, DC
    • Related Report
      2008 Annual Research Report
  • [Presentation] AFM Observation of membrane proteins suspended over nanowells : structure and functional analysis2008

    • Author(s)
      K. Sumitomo, Y. Shinozaki, N. Kasai, H. Nakashima, A. M. Siitonen, K. Torimitsu. C. S. Ramanujan. J. F. Ryan
    • Organizer
      Workshop of the UK-Japan Bionanotechnology Collaboration
    • Place of Presentation
      Kobe, Japan
    • Related Report
      2008 Annual Research Report
  • [Book] 分子エレクトロニクスの基盤技術と将来展望(第4章バイオ評価技術)2009

    • Author(s)
      鳥光慶一、島田明佳、古川由里子
    • Total Pages
      14
    • Publisher
      シーエムシー出版
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 脂質二分子膜基板2010

    • Inventor(s)
      住友弘二、篠崎陽一、中島寛、島田明佳、河西奈保子、鳥光慶一
    • Industrial Property Rights Holder
      日本電信電話株式会社
    • Industrial Property Number
      2010-026703
    • Filing Date
      2010-02-09
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 膜タンパク質機能測定システムおよび膜タンパク質機能測定方法2009

    • Inventor(s)
      篠崎陽一、住友弘二、河西奈保子、中島寛、鳥光慶一
    • Industrial Property Rights Holder
      日本電信電話株式会社
    • Industrial Property Number
      2009-169079
    • Filing Date
      2009-07-17
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 膜タンパク質機能測定基板および 膜タンパク質機能測定方法2008

    • Inventor(s)
      篠崎陽一、住友弘二、中島寛、河西奈保子、鳥光慶一
    • Industrial Property Rights Holder
      日本電信電話株式会社
    • Industrial Property Number
      2008-296830
    • Filing Date
      2008-11-20
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 膜タンパク質の脂質膜内配向評価方法2008

    • Inventor(s)
      河西奈保子、篠崎陽一、住友弘二、鳥光慶一
    • Industrial Property Rights Holder
      日本電信電話株式会社
    • Industrial Property Number
      2008-031994
    • Filing Date
      2008-12-16
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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