Development of transgenic avian platform for the production of biologics
| Project/Area Number |
20360376
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Kyushu University |
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Principal Investigator |
KAMIHIRA Masamichi Kyushu University, 工学研究院, 教授 (40202022)
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| Co-Investigator(Kenkyū-buntansha) |
KAWABE Yoshinori 九州大学, 工学研究院, 助教 (30448401)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥18,460,000 (Direct Cost: ¥14,200,000、Indirect Cost: ¥4,260,000)
Fiscal Year 2010: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2009: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2008: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000)
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| Keywords | 生物・生体工学 / バイオテクノロジー / トランスジェニック鳥類 / バイオロジクス / ウイルスベクター |
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| Research Abstract |
Transgenic chicken bioreactor systems were developed for the production of pharmaceutical proteins using the avian transgenic technology. In the present study, development of oviduct-specific gene expression systems, control strategy for sugar chain modification of glycoprotein products, and biologics production suitable for transgenic chicken bioreactors were examined to establish the procedure as a biologics production system.
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Report
(4 results)
Research Products
(36 results)
