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Neurophysiological and neuroanatomical analyses of brain mechanisms subserving spontaneous initiation of behavior in invertebrates

Research Project

Project/Area Number 20370028
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Animal physiology/Animal behavior
Research InstitutionHokkaido University

Principal Investigator

TAKAHATA Masakazu  Hokkaido University, 大学院・理学研究院, 教授 (10111147)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2010: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2009: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2008: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Keywords行動生理 / 神経行動 / 神経生物 / 甲殻類 / ザリガニ / 自発行動 / 脳 / シナプス統合 / 神経回路網
Research Abstract

Extracellular recordings from the brain of crayfish, Procambarus clarkii, fixed on a sphere-type treadmill have revealed for the first time in invertebrates that a specific set of descending interneurons show a noticeable increase in their spike activity, i.e., the readiness activity, before the animal spontaneously initiates locomotor behavior. Using intracellular recording and staining techniques, we could identify those readiness discharge neurons by characterizing their physiological and morphological features in the brain. Furthermore, we showed that the readiness activity is shaped by sequential synaptic excitation and inhibition.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (41 results)

All 2011 2010 2009 2008 Other

All Journal Article (15 results) (of which Peer Reviewed: 15 results) Presentation (20 results) Book (5 results) Remarks (1 results)

  • [Journal Article] Sequential synaptic excitation and inhibition shapes readiness discharge for voluntary behavior2011

    • Author(s)
      Kagaya K., Takahata M.
    • Journal Title

      Science 332

      Pages: 365-368

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sequential synaptic excitation and inhibition shapes readiness discharge for voluntary behavior2011

    • Author(s)
      K.Kagaya
    • Journal Title

      Science

      Volume: (in press)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A behavioral analysis of force-controlled operant tasks in American lobster2010

    • Author(s)
      Tomina Y., Takahata M.
    • Journal Title

      Physiol.&Behav. 101

      Pages: 108-116

    • NAID

      120002277522

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Readiness discharge for spontaneous initiation of walking in crayfish2010

    • Author(s)
      Kagaya K., Takahata M.
    • Journal Title

      J.Neurosci. 30

      Pages: 1348-1362

    • NAID

      120002261715

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 脳と神経系:ザリガニの脳と神経における構造と機能の連関をめぐって2010

    • Author(s)
      高畑雅一
    • Journal Title

      ザリガニの生物学(川井唯史・高畑雅一編著) (北海道大学出版会)

      Pages: 155-191

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Readiness discharge for spontaneous initiation of walking in crayfish2010

    • Author(s)
      K.Kagaya
    • Journal Title

      J. Neurosci.

      Volume: 30 Pages: 1348-1362

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A behavioral analysis of force-controlled operant tasks in American lobster2010

    • Author(s)
      Y.Tomina
    • Journal Title

      Physiol. & Behav.

      Volume: 101 Pages: 108-116

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Readiness discharge for spontaneous initiation of walking in crayfish2010

    • Author(s)
      Kagaya, K.
    • Journal Title

      J.Neurosci. 30

      Pages: 1348-1362

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ザリガニの学習と記憶2009

    • Author(s)
      高畑雅一
    • Journal Title

      動物は何を考えているのか?(日本比較生理生化学会編)(共立出版)

      Pages: 47-64

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Static electric field detection and behavioural avoidance in cockroaches2008

    • Author(s)
      Newland P.L., Hunt E., Sharkh S.M., Hama N., Takahata M., Jackson C.W.
    • Journal Title

      J.Exp.Biol. 211

      Pages: 3682-3690

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of intertebrate brain platform : Management of research resources for invertebrate neuro- science and neuroethology2008

    • Author(s)
      Ikeno H., Kanzaki R., Aonuma H., Takahata M., Mizunami M., Yasuyama K., Matsui N., Yokohari F., Usui S.
    • Journal Title

      ICONIP(Springer- Verlag, Berlin) Part II

      Pages: 905-914

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 甲殻類の姿勢制御とその神経機構2008

    • Author(s)
      高畑雅一
    • Journal Title

      昆虫ミメティクス~昆虫の設計に学ぶ~(下澤楯夫・針山孝彦篇)(NTS)

      Pages: 522-532

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of active conductance distribution over dendrites on the synaptic integration in an identified nonspildng interneuron2008

    • Author(s)
      Takashima, A.
    • Journal Title

      PLoS ONE 3

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Electromyographic characterization of walking behavior initiated spontaneously in crayfish2008

    • Author(s)
      Chikamoto, K.
    • Journal Title

      Zool. Sci. 25

      Pages: 783-792

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Static electric field detection and behavioural avoidance in cockroaches2008

    • Author(s)
      Newland, P. L.
    • Journal Title

      J. Exp. Biol. 211

      Pages: 3682-3690

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] アメリカザリガニの自発性歩行開始・制御における脳内神経細胞の機能的役割2011

    • Author(s)
      加賀谷勝史
    • Organizer
      第23回自律分散システム・シンポジウム
    • Place of Presentation
      北海道大学・札幌
    • Year and Date
      2011-01-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Characterization of brain neurons involved in spontaneously initiated walking in crayfish2011

    • Author(s)
      K.Kagaya
    • Organizer
      The Society for Integrative and Comparative Biology Annual Meeting 2011
    • Place of Presentation
      Salt Lake City, Utah, USA
    • Year and Date
      2011-01-06
    • Related Report
      2010 Annual Research Report
  • [Presentation] Characterization of brain neurons involved in spontaneously initiated walking in crayfish2011

    • Author(s)
      加賀谷勝史, 高畑雅一
    • Organizer
      Society for Integrative and Comparative Biology Annual Meeting 2011
    • Place of Presentation
      Salt Lake City Convention Center, Salt Lake City, Utah, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] ザリガニ自発性歩行開始・継続の移行にかかわる下行性・上行性神経活動2010

    • Author(s)
      加賀谷勝史
    • Organizer
      日本動物学会第81会大会
    • Place of Presentation
      東京大学・東京
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] アメリカウミザリガニのグリッピングによるオペラント学習能の検証2010

    • Author(s)
      冨菜雄介
    • Organizer
      日本比較生理生化学会第32回大会
    • Place of Presentation
      九州産業大学・福岡
    • Year and Date
      2010-07-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] アメリカザリガニにおける歩行運動の集団符号化による神経制御機構2010

    • Author(s)
      加賀谷勝史
    • Organizer
      日本比較生理生化学会第32回大会
    • Place of Presentation
      九州産業大学・福岡
    • Year and Date
      2010-07-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 拘束条件下のアメリカウミザリガニにおける光刺激に対するオペラント弁別学習能の検証2010

    • Author(s)
      冨菜雄介・高畑雅一
    • Organizer
      日本動物行動学会第29回大会
    • Place of Presentation
      沖縄県男女共同参画センター 那覇市
    • Related Report
      2010 Final Research Report
  • [Presentation] ザリガニ自発性歩行開始・継続の移行にかかわる下行性・上行性神経活動2010

    • Author(s)
      加賀谷勝史・高畑雅一
    • Organizer
      日本動物学会第81回大会
    • Place of Presentation
      東京大学 東京都目黒区
    • Related Report
      2010 Final Research Report
  • [Presentation] ザリガニの行動とその神経機構2010

    • Author(s)
      高畑雅一
    • Organizer
      日本比較生理生化学会第32回大会
    • Place of Presentation
      九州産業大学 福岡市
    • Related Report
      2010 Final Research Report
  • [Presentation] アメリカザリガニにおける歩行方向の集団符号化による神経制御機構2010

    • Author(s)
      加賀谷勝史・高畑雅一
    • Organizer
      日本比較生理生化学会第32回大会
    • Place of Presentation
      九州産業大学福岡市
    • Related Report
      2010 Final Research Report
  • [Presentation] アメリカウミザリガニのグリッピングによるオペラント学習能の検証2010

    • Author(s)
      冨菜雄介・高畑雅一
    • Organizer
      日本比較生理生化学会第32回大会
    • Place of Presentation
      九州産業大学 福岡市
    • Related Report
      2010 Final Research Report
  • [Presentation] 自発性行動開始の神経制御機構:ザリガニ下行性神経活動の歩行運動開始における役割2009

    • Author(s)
      加賀谷勝史
    • Organizer
      日本動物学会第80回大会
    • Place of Presentation
      静岡市
    • Year and Date
      2009-09-17
    • Related Report
      2009 Annual Research Report
  • [Presentation] アメリカウミザリガニはオペラント学習が可能か?:マニピュレーションタスクによる行動分析学的検証2009

    • Author(s)
      冨菜雄介・高畑雅一
    • Organizer
      日本動物行動学会第28回大会
    • Place of Presentation
      筑波大学 つくば市
    • Related Report
      2010 Final Research Report
  • [Presentation] 自発性行動開始の制御機構:ザリガニ下行性神経活動の歩行運動開始における役割2009

    • Author(s)
      加賀谷勝史・高畑雅一
    • Organizer
      日本動物学会第80回大会
    • Place of Presentation
      静岡県コンベンションアーツセンター 静岡市
    • Related Report
      2010 Final Research Report
  • [Presentation] アメリカウミザリガニはオペラント学習が可能か?マニピュレーションタスクによる行動分析学的検証2009

    • Author(s)
      冨菜雄介
    • Organizer
      日本動物行動学会第28回大会
    • Place of Presentation
      つくば市
    • Related Report
      2009 Annual Research Report
  • [Presentation] ザリガニの自発性歩行運動開始にかかわる局所性脳内シナプス表現2008

    • Author(s)
      加賀谷勝史
    • Organizer
      日本動物学会第79回大会
    • Place of Presentation
      福岡大学
    • Year and Date
      2008-09-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] ザリガニ前運動性及び機械感覚性ノンスパイキング介在神経樹状突起における機能的差異2008

    • Author(s)
      高島總・高畑雅一
    • Organizer
      日本動物学会第79回大会
    • Place of Presentation
      福岡大学福岡市
    • Related Report
      2010 Final Research Report
  • [Presentation] ザリガニの自発性歩行運動開始にかかわる局所性脳内シナプス表現2008

    • Author(s)
      加賀谷勝史・高畑雅一
    • Organizer
      日本動物学会第79回大会
    • Place of Presentation
      福岡大学 福岡市
    • Related Report
      2010 Final Research Report
  • [Presentation] ザリガニの自発性歩行の開始・維持・停止における並列下行性制御機構2008

    • Author(s)
      加賀谷勝史・高畑雅一
    • Organizer
      日本比較生理生化学会第30回大会
    • Place of Presentation
      北海道大学 札幌市
    • Related Report
      2010 Final Research Report
  • [Presentation] 行動遂行時及び感覚刺激に対するザリガニ脳内各微小構造の神経応答2008

    • Author(s)
      濱徳行・土田義和・高畑雅一
    • Organizer
      日本比較生理生化学会第30回大会
    • Place of Presentation
      北海道大学 札幌市
    • Related Report
      2010 Final Research Report
  • [Book] ザリガニの生物学(川井唯史・高畑雅一(編著))2010

    • Author(s)
      川井唯史・高畑雅一
    • Total Pages
      556
    • Publisher
      北海道大学出版会
    • Related Report
      2010 Final Research Report
  • [Book] ザリガニの生物学2010

    • Author(s)
      高畑雅一
    • Total Pages
      558
    • Publisher
      北海道大学出版会
    • Related Report
      2010 Annual Research Report
  • [Book] ザリガニの生物学(川井唯史・高畑雅一編著)2010

    • Author(s)
      高畑雅一
    • Total Pages
      558
    • Publisher
      北海道大学出版会
    • Related Report
      2009 Annual Research Report
  • [Book] 動物は何を考えているのか?(曽我部正博編)2009

    • Author(s)
      高畑雅一
    • Total Pages
      262
    • Publisher
      共立出版
    • Related Report
      2009 Annual Research Report
  • [Book] 昆虫ミメテイクス〜昆虫の設計に学ぶ〜(下澤楯夫・針山孝彦篇)2008

    • Author(s)
      高畑雅一
    • Total Pages
      1074
    • Publisher
      株式会社エヌ・ティー・エス
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://crayfish3.sci.hokudai.ac.jp/

    • Related Report
      2010 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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