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Structure and Function of MBP-ligand oligosaccharides isolated from SW1116 cells

Research Project

Project/Area Number 20370052
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Functional biochemistry
Research InstitutionRitsumeikan University

Principal Investigator

KAWASAKI Toshisuke  Ritsumeikan University, 総合理工学研究機構, 教授 (50025706)

Co-Investigator(Kenkyū-buntansha) MA BRUCE  立命館大学, 立命館グローバル・イノベーション研究機構, 准教授 (00378788)
KAWASAKI Nobuko  立命館大学, 総合理工学研究機構, 教授 (70077676)
Co-Investigator(Renkei-kenkyūsha) ISHIGURO Masaji  新潟薬科大学, 応用生物科学部, 教授 (10280687)
ISHIDA Hideharu  岐阜大学, 応用生物科学部, 教授 (20203002)
KATO Koichi  名古屋市立大学, 薬学研究科, 教授 (20211849)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥20,930,000 (Direct Cost: ¥16,100,000、Indirect Cost: ¥4,830,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2009: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2008: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Keywords癌 / 糖鎖 / 先天性免疫 / 動物レクチン / 臨床試料 / がん / 腫瘍マーカー / マンナン結合タンパク質 / ルイスaエピトープ / ルイスxエピトープ / コンピュータモデリング / 糖鎖パターン認識 / 免疫学 / 生体分子 / 生理活性
Research Abstract

Based on the biochemical data obtained, we proposed a computer modeling of the molecular complex of the serum mannan-binding protein and its high affinity ligand oligosaccharides on SW1116 cells. Immunohistochemical analysis indicated that the MBP-ligand oligosaccharides are novel tumor marker candidates.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (81 results)

All 2011 2010 2009 2008 Other

All Journal Article (19 results) (of which Peer Reviewed: 19 results) Presentation (53 results) Book (8 results) Remarks (1 results)

  • [Journal Article] Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) recognizes a novel ligand, Mac-2-binding protein, characteristically expressed on human colorectal carcinomas2011

    • Author(s)
      Nonaka M, Ma BY, Imaeda H, Kawabe K, Kawasaki N, Hodohara K, Kawasaki N, Andoh A, Fujiyama Y, Kawasaki T
    • Journal Title

      J.Biol.Chem. (印刷中(掲載確定))

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) recognizes a novel ligand, Mac-2-binding protein, characteristically expressed on human colorectal carcinomas2011

    • Author(s)
      Motohiro Nonaka
    • Journal Title

      J.Biol.Chem.

      Volume: (印刷中 掲載確定)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recognition of Endogenous Ligands by C-Type Lectins: Interaction of Serum Mannan-binding Protein with Tumor-associated Oligosaccharide Epitopes2010

    • Author(s)
      Kawasaki N, Kawasaki T
    • Journal Title

      Trends Glycosci. Glycotechnol. 22

      Pages: 141-151

    • NAID

      10027508427

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recognition of Endogenous Ligands by C-Type Lectins : Interaction of Serum Mannan-binding Protein with Tumor-associated Oligosaccharide Epitopes2010

    • Author(s)
      Nobuko Kawasaki
    • Journal Title

      Trends Glycosci.Glycotechnol.

      Volume: 22(125) Pages: 141-151

    • NAID

      10027508427

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] HNK-1 glyco-epitope is essential for normal spine morphogenesis in developing hippocampal neurons2009

    • Author(s)
      Morita I, Kakuda S, Takeuchi Y,Kawasaki T, Oka S
    • Journal Title

      Neuroscience 164

      Pages: 1685-1694

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] HNK-1 glyco-epitope regulates the stability of the glutamate receptor subunit GluR2 on the neuronal cell surface2009

    • Author(s)
      Morita I, Kakuda S, Takeuchi Y, Itoh S, Kawasaki N, Kizuka Y, Kawasaki T, Oka S
    • Journal Title

      J Biol.Chem. 284

      Pages: 30209-30217

    • Related Report
      2010 Final Research Report 2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulated expression of HNK-1 carbohydrate is essential for medaka (Oryzias latipes) embryogenesis2009

    • Author(s)
      Anzai D, Tonoyama Y, Ikeda A, Kawasaki T, Oka S
    • Journal Title

      Glycobiology 19

      Pages: 868-878

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of the interaction between serum mannan-binding protein and nucleic acid ligands2009

    • Author(s)
      Nakamura N, Nonaka M, Ma BY, Matsumoto S, Kawasaki N, Asano S, Kawasaki T
    • Journal Title

      J.Leukoc.Biol. 86

      Pages: 737-748

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Essential role of beta1,4-galactosyltransferase 2 during medaka (Oryzias latipes) gastrulation2009

    • Author(s)
      Tonoyama Y, Anzai D, Ikeda A, Kakuda S, Kinoshita M, Kawasaki T, Oka S
    • Journal Title

      Mech.Dev. 126

      Pages: 580-594

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Highly Fucosylated N-Glycan Ligands for Mannan-binding Protein Expressed Specifically on CD26 (DPPVI) Isolated from a Human Colorectal Carcinoma Cell Line, SW11162009

    • Author(s)
      Kawasaki N, Lin CW, Inoue R, Khoo KH, Kawasaki N, Ma BY, Oka S, Ishiguro M, Sawada T, Ishida H, Hashimoto T, Kawasaki T
    • Journal Title

      Glycobiology 19

      Pages: 437-450

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] HNK-1 glyco-epitope is essential for normal spine morphogenesis in developing hippocampal neurons2009

    • Author(s)
      Morita I, Kakuda S, Takeuchi Y, Kawasaki T, Oka S
    • Journal Title

      Neuroscience 164

      Pages: 1685-1694

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulated expression of HNK-1 carbohydrate is essential for medaka(Oryzias latipes)embryogenesis2009

    • Author(s)
      Anzai D, Tonoyama Y, Ikeda A, Kawasaki T, Oka S
    • Journal Title

      Glycobiology 19

      Pages: 868-878

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of the interaction between serum mannan-binding protein and nucleic acid ligands2009

    • Author(s)
      Nakamura N, Nonaka M, MaBY, Matsumoto S, Kawasaki N, Asano S, Kawasaki T.
    • Journal Title

      Journal of Leukocyte Biology 86

      Pages: 737-748

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Essential role of betal, 4-galactosyltransferase 2 during medaka (Oryzias latipes) gastrulation2009

    • Author(s)
      Tonoyama Y, Anzai D, Ikeda A, Kakuda S, Kinoshita M, Kawasaki T, Oka S
    • Journal Title

      Mechanisms of Development (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Highly Fucosylated N-Glycan Ligands for Mannan-binding Protein Expressed Specifically on CD26 (DPPVI) Isolated from a Human Colorectal Carcinoma Cell Line, SW11162009

    • Author(s)
      Kawasaki N, Lin CW, Inoue R, Khoo KH, Kawasaki N, Ma BY, Oka S, Ishiguro M, Sawada T, Ishida H, Hashimoto T, Kawasaki T.
    • Journal Title

      Glycobiology 19

      Pages: 437-450

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The lectin Jacalin induces human B lymphocyte apoptosis through glycosylation-dependent interaction with CD452009

    • Author(s)
      Ma BY, Yoshida K, Baba M, Nonaka M, Matsumoto S, Kawasaki N, Asano S, Kawasaki T.
    • Journal Title

      Immunology (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The lectin Jacalin induces human B lymphocyte apoptosis through glycosylation-dependent interaction with CD452008

    • Author(s)
      Ma BY, Yoshida K, Baba M, Nonaka M, Matsumoto S, Kawasaki N, Asano S, Kawasaki T
    • Journal Title

      Immunology 127

      Pages: 477-488

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development and application of high performance liquid chromatography map of glucuronyl N-glycans2008

    • Author(s)
      Yagi H, Yamada K, Ohno E, Utsumi M, Yamaguchi Y, Kurimoto E, Takahashi N, Oka S, Kawasaki T, Kato K
    • Journal Title

      Open Glycoscience 1

      Pages: 8-11

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development and application of high performance liquid chroma tography map of glucuronyl N-glycans2008

    • Author(s)
      Yagi H, Yamada K, Ohno E, Utsumi M, Yamaguchi Y, Kurimoto E, Takahashi N, Oka S, Kawasaki T, Kato K
    • Journal Title

      Open Glycoscience 1

      Pages: 8-11

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] C-Type Lectin DC-SIGN interacts with Mac-2BP Expressed on Human Colon Tumors2010

    • Author(s)
      Nonaka M, Ma BY, Yamaguchi K, Kawasaki N, Kawasaki T
    • Organizer
      第33回日本分子生物学会年会 第83回日本生物学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Year and Date
      2010-12-10
    • Related Report
      2010 Final Research Report
  • [Presentation] C-type Lectin DC-SIGN interacts with Mac-2BP Expressed on Human Colon Tumors2010

    • Author(s)
      野中元裕
    • Organizer
      第33回日本分子生物学会年会第83回日本生物学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Year and Date
      2010-12-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] ユニークなJCGGDBの開発2010

    • Author(s)
      川嵜敏祐、鹿内俊秀
    • Organizer
      第8回日本糖鎖科学コンソーシアムシンポジウム
    • Place of Presentation
      東京コンファレンスセンター品川(東京)
    • Year and Date
      2010-11-30
    • Related Report
      2010 Final Research Report
  • [Presentation] ユニークなJCGGDBの開発2010

    • Author(s)
      川嵜敏祐
    • Organizer
      第8回日本糖鎖科学コンソーシアムシンポジウム
    • Place of Presentation
      東京コンファレンスセンター・品川(東京)
    • Year and Date
      2010-11-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Mac-2BP Expressed on Human Colon Carcinomas is a novel ligand for DC-SIGN2010

    • Author(s)
      Nonaka M, Ma BY, Matsumoto S, Yamaguchi K, Kawasaki N, Kawasaki T
    • Organizer
      2010 Annual Conference of the Society for GLycobiology
    • Place of Presentation
      Florida (USA)
    • Year and Date
      2010-11-10
    • Related Report
      2010 Final Research Report
  • [Presentation] Mac-2BP Expressed on Human Colon Carcinomas is a novel ligand for DC-SIGN2010

    • Author(s)
      Motohiro Nonaka
    • Organizer
      2010 Annual Conference of the Society for Glyco-biology
    • Place of Presentation
      Florida, USA
    • Year and Date
      2010-11-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] Recognition of Tumor-associated Oligosaccharides by Serum Mannan-binding Protein2010

    • Author(s)
      Kawasaki T, Nonaka M, Ma BY
    • Organizer
      2010 Annual Conference of the Society for GLycobiology
    • Place of Presentation
      Florida (USA)
    • Year and Date
      2010-11-07
    • Related Report
      2010 Final Research Report
  • [Presentation] Recognition of Tumor-associated Oligosaccharides by Serum Mannan-binding Protein2010

    • Author(s)
      Toshisuke Kawasaki
    • Organizer
      2010 Annual Conference of the Society for Glyco-biology
    • Place of Presentation
      Florida, USA
    • Year and Date
      2010-11-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] C-Type Lectin DC-SIGN Recognizes Glycans of Mac-2BP Expressed on Colorectal Cancer2010

    • Author(s)
      Nonaka M, Ma BY, Matsumoto S, Yamaguchi K, Kawasaki N, Kawasaki T
    • Organizer
      25th International Carbohydrate Symposium, 2010
    • Place of Presentation
      幕張メッセ(千葉県)
    • Year and Date
      2010-08-02
    • Related Report
      2010 Final Research Report
  • [Presentation] C-type Lectin DC-SIGN Recognizes Glycans of Mac-2BP Expressed on Colorectal Cancer2010

    • Author(s)
      Motohiro Nonaka
    • Organizer
      25^<th> International Carbohydrate Symposium, 2010
    • Place of Presentation
      幕張メッセ(千葉)
    • Year and Date
      2010-08-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Interaction of serum mannan-binding protein with tumor-associated oligosaccharides2010

    • Author(s)
      川嵜敏祐
    • Organizer
      Glyco T 2010
    • Place of Presentation
      KFCホール(東京都)
    • Year and Date
      2010-07-31
    • Related Report
      2010 Final Research Report
  • [Presentation] Interaction of Serum Mannan-binding Protein with Tumor-associated Oligosaccharides2010

    • Author(s)
      川嵜敏祐
    • Organizer
      Glyco T 2010
    • Place of Presentation
      KFCホール(東京)
    • Year and Date
      2010-07-31
    • Related Report
      2010 Annual Research Report
  • [Presentation] Japan Consortium for Glycobiology and Glycotechnology DataBase2009

    • Author(s)
      Shikanai T, Kawasaki T, Narimatsu H, 他
    • Organizer
      20th International Symposium on Glycoconjugate (GLYCO XX)
    • Place of Presentation
      Puerto Rico (USA)
    • Year and Date
      2009-11-29
    • Related Report
      2010 Final Research Report
  • [Presentation] Characteristic interaction of serum mannan-binding protein with nucleic acids2009

    • Author(s)
      Nonaka M, Ma BY, Matsumoto S, Kawasaki N, Kawasaki T
    • Organizer
      2009 Annual Meeting of the Society for Glycobiology
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2009-11-13
    • Related Report
      2010 Final Research Report
  • [Presentation] Characteristic interaction of serum mannan-binding protein with nucleicacids2009

    • Author(s)
      Nonaka M, MaBY, Matsumoto S, Kawasaki N, Kawasaki T
    • Organizer
      2009 Annual Meeting of the Society for Glycobiology
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2009-11-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] A mode of glycan recognition by the serum mannan-binding protein2009

    • Author(s)
      川嵜敏祐
    • Organizer
      3rd Core to Core Satellite Meeting of the Japanese and German Glycobiology Study Groups
    • Place of Presentation
      Keln (Germany)
    • Year and Date
      2009-11-10
    • Related Report
      2010 Final Research Report
  • [Presentation] A mode of glycan recognition by the serum mannan-binding protein2009

    • Author(s)
      Kawasaki T
    • Organizer
      3rd Core to Core Satellite Meeting of the Japanese and German Glycobiology Study Groups
    • Place of Presentation
      Keln, Germany
    • Year and Date
      2009-11-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] 血清型マンナン結合タンパク質と核酸の相互作用の解析とその生物学的意義2009

    • Author(s)
      野中元裕、Ma Bruce Yong、松本尚吾、川嵜伸子、川嵜敏祐
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2009-10-21
    • Related Report
      2010 Final Research Report
  • [Presentation] CD26/DPPIVの糖鎖構造と酵素活性に関する研究2009

    • Author(s)
      山口圭子、大坪和明、荒川健司、Khoo Kay-Hooi, 川崎ナナ、中尾広美、野中元裕、Ma Bruce Yong、川嵜伸子、川嵜敏祐
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2009-10-21
    • Related Report
      2010 Final Research Report
  • [Presentation] 血清型マンナン結合タンパク質による核酸の認識とその意義2009

    • Author(s)
      野中元裕、Ma Bruce Yong、中村奈都子、松本尚吾、川嵜伸子、川嵜敏祐
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      飛騨・世界生活文化センター(岐阜県)
    • Year and Date
      2009-09-11
    • Related Report
      2010 Final Research Report
  • [Presentation] 血清型マンナン結合タンパク質による核酸の認識とその意義2009

    • Author(s)
      野中元裕、Ma Bruce Yong、中村奈都子、松本尚吾、川嵜伸子、川嵜敏祐
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      飛騨・世界生活文化センター(岐阜)
    • Year and Date
      2009-09-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] 日本糖鎖科学コンソーシアムのデータベース2009

    • Author(s)
      鹿内俊秀、川嵜敏祐、成松久, 他
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      飛騨・世界生活文化センター(岐阜県)
    • Year and Date
      2009-09-09
    • Related Report
      2010 Final Research Report
  • [Presentation] ルイスAモノマーおよびオリゴマー糖鎖を用いた抗ルイス糖鎖抗体の反応特異性解析2009

    • Author(s)
      山口圭子、中尾広美、長尾和弥、石田秀治、木曽真、福井成行、野中元裕、Ma Bruce Yong、川嵜伸子、川嵜敏祐
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      飛騨・世界生活文化センター(岐阜県)
    • Year and Date
      2009-09-09
    • Related Report
      2010 Final Research Report
  • [Presentation] Characteristic recognition and biological significance of the interaction between serum mannan-binding protein and nucleic acids2009

    • Author(s)
      Nonaka M, Ma BY, Matsumoto S, Kawasaki N, Kawasaki T
    • Organizer
      21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai (China)
    • Year and Date
      2009-08-02
    • Related Report
      2010 Final Research Report
  • [Presentation] Jacalin induces B cell death through glycosylation-dependent interaction with CD452009

    • Author(s)
      Ma BY, Nonaka M, Kawasaki N, Kawasaki T
    • Organizer
      21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai (China)
    • Year and Date
      2009-08-02
    • Related Report
      2010 Final Research Report
  • [Presentation] Glyco-signal and animal lectin2009

    • Author(s)
      川嵜敏祐
    • Organizer
      Invited lecture at College of Pharmacy, Busan National University
    • Place of Presentation
      Busan (Korea)
    • Year and Date
      2009-07-31
    • Related Report
      2010 Final Research Report
  • [Presentation] Interaction of Mannan-binding Protein and its High Affinity Ligands Expressed on CD26 (DPPVI) Isolated from a human Colorectal Carcinoma, SW11162009

    • Author(s)
      Kawasaki T, Kawasaki N, Khoo KH, Nonaka M, Ma BY
    • Organizer
      15th European Carbohydrate Symposium
    • Place of Presentation
      Vienna (Austria)
    • Year and Date
      2009-07-21
    • Related Report
      2010 Final Research Report
  • [Presentation] Japan Consortium for Glycobiology and Glycotechnology Database2009

    • Author(s)
      Shikanai T, Simma Y, Kawasaki T, Narimatsu H, et al.
    • Organizer
      20^<th> International Symposium on Glycoconjugate(GLYCO XX)
    • Place of Presentation
      Puerto Rico
    • Related Report
      2009 Annual Research Report
  • [Presentation] CD26/DPPIVの糖鎖構造と酵素活性に関する研究2009

    • Author(s)
      山口圭子、大坪和明、荒川健司、Khoo Kay-Hooi, 川崎ナナ、中尾広美、野中元裕、Ma Bruce Yong、川嵜伸子、川嵜敏祐
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 血清型マンナン結合タンパク質と核酸の相互作用の解析とその生物学的意義2009

    • Author(s)
      野中元裕、Ma Bruce Yong、松本尚吾、川嵜伸子、川嵜敏祐
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Related Report
      2009 Annual Research Report
  • [Presentation] ルイスAモノマーおよびオリゴマー糖鎖を用いた抗ルイス糖鎖抗体の反応特異性解析2009

    • Author(s)
      山口圭子、中尾広美、長尾和弥、石田秀治、木曽真、福井成行、野中元裕、Ma Bruce Yong、川嵜伸子、川嵜敏祐
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      飛騨・世界生活文化センター(岐阜)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 日本糖鎖科学コンソーシアムのデータベース2009

    • Author(s)
      鹿内俊秀、新間陽一、鈴木芳典、奥田修二郎、川嵜敏祐、成松久, 他
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      飛騨・世界生活文化センター(岐阜)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Jacalin induces B cell death through glycosylation-dependent interaction with CD452009

    • Author(s)
      Ma BY, Nonaka M, Kawasaki N, Kawasaki T
    • Organizer
      21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai International Conference Center, China
    • Related Report
      2009 Annual Research Report
  • [Presentation] Characteristic recognition and biological significance of the interaction between serum mannan-binding protein and nucleic acids2009

    • Author(s)
      Nonaka M, Ma BY, Matsumoto S, Kawasaki N, Kawasaki T
    • Organizer
      21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology
    • Place of Presentation
      Shanghai International Conference Center, China
    • Related Report
      2009 Annual Research Report
  • [Presentation] Interaction of mannan-binding protein and its high affinity ligands expressed on CD26(DPPIV)isolated from a human colorectal carcinoma, SW11162009

    • Author(s)
      Kawasaki T, Kawasaki N, Khoo KH, Yamaguchi K, Nonaka M, Ma BY
    • Organizer
      15th European carbohydrate symposium
    • Place of Presentation
      Vienna, Austria
    • Related Report
      2009 Annual Research Report
  • [Presentation] マンナン結合タンパク質に対して高親和性結合を示すリガンド糖鎖の構造的特徴2008

    • Author(s)
      山口圭子、川嵜伸子、Kay-Hooi Khoo、石黒正路、澤田敏彦、川崎ナナ、中尾広美、Bruce Yong Ma、川嵜敏祐
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2008-12-12
    • Related Report
      2010 Final Research Report
  • [Presentation] 樹状細胞C型レクチンDC-SIGN による結腸癌細胞表面糖鎖の認識と腫瘍免疫の調節機構2008

    • Author(s)
      野中元裕、Bruce YongMa、川嵜伸子、川嵜敏祐
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2008-12-12
    • Related Report
      2010 Final Research Report
  • [Presentation] マンナン結合タンパク質に対して高親和性結合を示すリガンド糖鎖の構造的特徴2008

    • Author(s)
      山口圭子, 川寄伸子, Kay-Hooi Khoo, 石黒正路, 澤田敏彦, 川崎ナナ, 中尾広美, Bruce Yong Ma, 川嵜敏祐
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 樹状細胞C型レクチンDC-SIGNによる結腸がん細胞表面糖鎖の認識と腫瘍免疫の調節機構2008

    • Author(s)
      野中元裕, Bruce Yong Ma川嵜伸子, 川嵜敏祐
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] Glycosylation-dependent interaction of the lectin Jacalin with CD45 induces B lymphocyte apoptosis2008

    • Author(s)
      Bruce Yong Ma、野中元裕、川嵜敏祐
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      国立京都国際会館(京都府)
    • Year and Date
      2008-12-03
    • Related Report
      2010 Final Research Report
  • [Presentation] Glycosylation-dependent interaction of the lectin Jacalin with CD45 induces B lymphocyte apoptosis2008

    • Author(s)
      Bruce Yong Ma, 野中元裕, 川嵜敏祐
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Functional Recognition of Colorectal Tumor-associated Lewis Glycans by C-type Lectin DC-SIGN2008

    • Author(s)
      Nonaka M, Ma BY, Kawasaki N, Kawasaki T
    • Organizer
      Annual Conference of the Society for Glycobiology
    • Place of Presentation
      Texas (USA)
    • Year and Date
      2008-11-14
    • Related Report
      2010 Final Research Report
  • [Presentation] Functional Recognition of Colorectal Tumor-associated Lewis Glycans by C-type Lectin DC-SIGN2008

    • Author(s)
      Nonaka M, Ma BY, Kawasaki N, Kawasaki T
    • Organizer
      Annual Conference of the Society for Glycobiology
    • Place of Presentation
      Texaas, USA
    • Year and Date
      2008-11-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] Jacalin-induced diverse immune responses through glycosylation-dependent interaction with CD45 on lymphocytes2008

    • Author(s)
      Nonaka M, Ma BY, Kawasaki N, Kawasaki T
    • Organizer
      8th Human Disease Glycomics/Proteome Initiative (HGPI) meeting
    • Place of Presentation
      Texas (USA)
    • Year and Date
      2008-11-13
    • Related Report
      2010 Final Research Report
  • [Presentation] Jacalin-induced diverse immune responses through glycosylation-dependent interaction with CD45 on lymphocytes2008

    • Author(s)
      Nonaka M, Ma BY, Kawasaki N, Kawasaki T
    • Organizer
      8th Human Diseas Glycomics/Proteome Initiative (HGPI)meeting
    • Place of Presentation
      Texa, USA
    • Year and Date
      2008-11-13
    • Related Report
      2008 Annual Research Report
  • [Presentation] 今なぜ糖鎖研究か2008

    • Author(s)
      川嵜敏祐
    • Organizer
      第4回産業医科大学大学院シンポジウム「細胞機能と病態における糖鎖の役割」
    • Place of Presentation
      産業医科大学(福岡県)
    • Year and Date
      2008-10-16
    • Related Report
      2010 Final Research Report
  • [Presentation] 今なぜ糖鎖研究か2008

    • Author(s)
      川嵜敏祐
    • Organizer
      第4回産業医科大学大学院シンポジウム「細胞機能と病態における糖鎖の役割」
    • Place of Presentation
      福岡県北九州市産業医科大学
    • Year and Date
      2008-10-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] CD45を標的とするJacalinによるBリンパ球のアポトーシスの誘導2008

    • Author(s)
      松本尚悟、Bruce Yong Ma、野中元裕、吉田香織、馬場亮人、川嵜伸子、浅野真司、川嵜敏祐
    • Organizer
      第28 回日本糖質学会年会
    • Place of Presentation
      つくば国際会議場(茨城県)
    • Year and Date
      2008-08-19
    • Related Report
      2010 Final Research Report
  • [Presentation] CD45を標的とするJacalinによるBリンパ球のアポトーシスの誘導2008

    • Author(s)
      松本尚悟 Bruce Yong Ma, 野中元裕, 吉田香織, 馬場亮人, 川嵜伸子, 浅野真司, 川寄敏祐
    • Organizer
      第28回日本糖質学会年会
    • Place of Presentation
      茨城県つくば市
    • Year and Date
      2008-08-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] Functional Implications for C-type Lectin DC-SIGN Recognizing Colorectal Tumor-Associated Lewis Glycans2008

    • Author(s)
      Nonaka M, Ma BY, Kawasaki N, Kawasaki T
    • Organizer
      23rd International Lectin Meeting
    • Place of Presentation
      Edinburgh (Scotland)
    • Year and Date
      2008-07-14
    • Related Report
      2010 Final Research Report
  • [Presentation] Functional Implications for C-type Lectin DC-SIGN Recognizing Colorectal Tumor-Associated Lewis Glycans2008

    • Author(s)
      Nonaka M, Ma BY, Kawasaki N, Kawasaki T
    • Organizer
      23^<rd> International Lectin Meeting
    • Place of Presentation
      Edinburgh, Scotland
    • Year and Date
      2008-07-14
    • Related Report
      2008 Annual Research Report
  • [Presentation] Specific Interaction of Mannan-Binding Protein with Highly Fucosylated Polylactosamine-type N-Glycans Isolated from Human Colorectal Carcinoma2008

    • Author(s)
      Kawasaki N, Khoo KH, Inoue R, Ma BY, Kawasaki T
    • Organizer
      23rd International Lectin Meeting
    • Place of Presentation
      Edinburgh (Scotland)
    • Year and Date
      2008-07-12
    • Related Report
      2010 Final Research Report
  • [Presentation] Specific Interaction of Mannan-Binding Protein with Highly Fucosylated Polylactosamine-type N-Glycans Isolated from Human Colorectal Carcinoma2008

    • Author(s)
      Kawasaki N, Khoo KH, Inoue R, Ma BY, Kawasaki T
    • Organizer
      23^<rd> International Lectin Meeting
    • Place of Presentation
      Edinburgh, Scotland
    • Year and Date
      2008-07-12
    • Related Report
      2008 Annual Research Report
  • [Book] 生物機能モデルと新しいリソース・リサーチツール第3章第4節HNK-1糖鎖合成酵素(グルクロン酸転移酵素)2011

    • Author(s)
      岡昌吾、川嵜敏祐
    • Total Pages
      7
    • Publisher
      株式会社エル・アイ・シー
    • Related Report
      2010 Final Research Report
  • [Book] GlycoScience Protocol Online Database (GlycoPOD)2011

    • Author(s)
      川嵜敏祐、鹿内俊秀、成松久編集
    • Publisher
      立命館大学、日本糖鎖科学統合データベース、産業技術総合研究所
    • URL

      http://jcggdb.jp/GlycoPOD/protocolListShow.action

    • Related Report
      2010 Final Research Report
  • [Book] 生物機能モデルと新しいリソース・リサーチツール 第3章糖鎖関連遺伝子ノックアウトマウス 第4節HNK-1糖鎖合成酵素(グルクロン酸転移酵素)2011

    • Author(s)
      岡昌吾
    • Total Pages
      7
    • Publisher
      株式会社エル・アイ・シー
    • Related Report
      2010 Annual Research Report
  • [Book] GlycoScience Protocol Online Database (GlycoPOD)2010

    • Author(s)
      川嵜敏祐 編集
    • Publisher
      立命館大学,日本糖鎖科学統合データベース、産業技術総合研究所
    • Related Report
      2010 Annual Research Report
  • [Book] 第3の生命鎖:糖鎖の謎が今、解る「脳を守るときの糖鎖の役割」2009

    • Author(s)
      川嵜敏祐
    • Total Pages
      9
    • Publisher
      クバプロ
    • Related Report
      2010 Final Research Report
  • [Book] 第3の生命鎖 : 糖鎖の謎が今、解る「脳を守るときの糖鎖の役割」2009

    • Author(s)
      川嵜敏祐
    • Total Pages
      9
    • Publisher
      クバプロ
    • Related Report
      2008 Annual Research Report
  • [Book] 蛋白質核酸酵素 増刊『糖鎖情報の独自性と普遍性』「樹状細胞レクチンによる糖鎖認識と免疫調節」2008

    • Author(s)
      野中元裕, Ma Bruce Yong, 川嵜敏祐
    • Total Pages
      6
    • Publisher
      共立出版
    • Related Report
      2010 Final Research Report
  • [Book] 蛋白質核酸酵素増刊『糖鎖情報の独自性と普遍性』「樹状細胞レクチンによる糖鎖認識と免疫調節」2008

    • Author(s)
      野中元裕, Ma Bruce Yong, 川嵜敏祐
    • Total Pages
      6
    • Publisher
      共立出版
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.glyco.is.ritsumei.ac.jp/RCG/

    • Related Report
      2010 Final Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

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