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Elucidation of protein dynamics as the control of protein function

Research Project

Project/Area Number 20370062
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biophysics
Research InstitutionNara Institute of Science and Technology

Principal Investigator

KATAOKA Mikio  Nara Institute of Science and Technology, 物質創成科学研究科, 教授 (30150254)

Co-Investigator(Kenkyū-buntansha) KAMIBKUBO Hironari  奈良先端科学技術大学院大学, 物質創成科学研究科, 准教授 (20311128)
YAMAZAKI Yoichi  奈良先端科学技術大学院大学, 物質創成科学研究科, 助教 (40332770)
Co-Investigator(Renkei-kenkyūsha) NAKAGAWA Hiroshi  日本原子力研究開発機構, 量子ビーム応用研究部門, 研究員 (20379598)
Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥20,540,000 (Direct Cost: ¥15,800,000、Indirect Cost: ¥4,740,000)
Fiscal Year 2010: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2009: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2008: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Keywords中性子散乱 / 蛋白質動力学 / 誘導折り畳み / 水和 / 動力学転移 / 動力学的転移 / 非天然構造 / 核酸分解酵素 / 中性子非干渉性散乱 / 平均二乗変位 / 水和水 / 動力学の階層性 / タンパク質動力学 / ボソンピーク / 中性子非弾性散乱 / 中性子準弾性散乱 / 振動スペクトル
Research Abstract

We succeeded to create an functionally active mutant without native structure under physiological condition. Using the mutant and wild type, neutron incoherent scattering experiments were performed under various hydration levels to reveal the protein dynamics required for function. Protein dynamics relevant for function is controlled by hydration water, and the hierarchical structures of protein dynamics are dependent on the conformational states. The essential property of hydration water is revealed to be the formation of hydrogen bond network between hydration water molecules.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (118 results)

All 2011 2010 2009 2008

All Journal Article (29 results) (of which Peer Reviewed: 29 results) Presentation (79 results) Book (10 results)

  • [Journal Article] Systematic alanine insertion reveals the essential regions that encode structure formation and activity of dihydrofolate reductase2011

    • Author(s)
      Rumi Shiba
    • Journal Title

      BIOPHYSICS

      Volume: 7 Pages: 1-10

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Percolation of hydration water as a control of protein dynamics2010

    • Author(s)
      Hiroshi Nakagawa, Mikio Kataoka
    • Journal Title

      Journal of Physical Society of Japan 79巻

      Pages: 83801-83801

    • NAID

      40017245105

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Non-local interaction responsible for the tertiarystructural formation of Staphylococcal nuclease.2010

    • Author(s)
      Shingo Kato, Hironari Kamikubo, Satoshi Hirano, Yoichi Yamazaki, Mikio Kataoka
    • Journal Title

      Biophysical Journal 98巻

      Pages: 678-786

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of conformational stateson protein dynamical transition2010

    • Author(s)
      Hiroshi, Hironari Kamikubo, Mikio Kataoka
    • Journal Title

      Biochimca et Biophysica Acta 1804巻

      Pages: 27-33

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of conformational states on protein dynamical transition2010

    • Author(s)
      Hiroshi Nakagawa
    • Journal Title

      Biochim.Biophys.Acta

      Volume: 1804 Pages: 27-33

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease2010

    • Author(s)
      Shingo Kato
    • Journal Title

      Biophys.J.

      Volume: 98 Pages: 678-786

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-Assembly and Enhanced Magnetic Properties of Three-dimensional Superlattice Structures Composed of Cube and Sphere-Shaped EuS Nanocrsytals2010

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Chem.Mat.

      Volume: 22 Pages: 1776-1781

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      Shun Hirota
    • Journal Title

      Proc.Natl.Acad.Sci.USA

      Volume: 107 Pages: 12854-12859

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Percolation of hydration water as a control of protein dynamics2010

    • Author(s)
      Hiroshi Nakagawa
    • Journal Title

      J.Phys.Soc.Jpn

      Volume: 79 Pages: 83801-83801

    • NAID

      40017245105

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Size-controlled aggregation of cube-shaped EuS nanocrystals with magneto-optic properties in solution2010

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Langmuir

      Volume: 27 Pages: 104-108

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] フォトアクティブイェロープロテインの中性子結晶構造解析2010

    • Author(s)
      上久保裕生
    • Journal Title

      RADIOISOTOPES

      Volume: 59 Pages: 289-297

    • NAID

      10026244827

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of conformational states on protein dynamical transition2010

    • Author(s)
      H.Nakagawa
    • Journal Title

      Biochim.Biophys.Acta 1804

      Pages: 27-33

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-local interaction responsible for the tertiary structural formation of Staphylococcal nuclease2010

    • Author(s)
      Shingo Kato
    • Journal Title

      Biophys.J 98

      Pages: 678-686

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-assembling Formation and Enhanced Magnetic Properties of Three-dimensional Super-lattics Structures Composed of Cube- and Sphere-shaped EuS nanocrsytals2010

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Chemistry of Materials 22(印刷中)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low barrier hydrogen bond inphotoactive yellow protein2009

    • Author(s)
      Shigeo Yamaguchi, Hironari Kamikubo, Kazuo Kurihara, Ryota Kuroki, Nobuo Niimura, Nobutaka Shimizu, Yoichi Yamazaki, MikioKataoka
    • Journal Title

      Proceedings of theNational Academy of Science of USA 106巻

      Pages: 440-444

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structural effects on the ultrafast photoisomerization of photoactive yellow protein : Transient absorption spectroscopy of two point mutants2009

    • Author(s)
      Pascale Changenet-Barret
    • Journal Title

      J.Phys.Chem.C. 113

      Pages: 11605-11613

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Self-aggregation of magnetic semiconductor EuS nanocrystals2009

    • Author(s)
      Atsushi Tanaka
    • Journal Title

      Thin Solid Films 518

      Pages: 870-872

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low barrier hydrogen bond in photoactive yellow protein2009

    • Author(s)
      Shigeo Yamaguchi
    • Journal Title

      Proceed ings of the National Academy of Science of USA 106

      Pages: 440-444

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hydration affects bothharmonic and enharmonic nature of proteindynamics2008

    • Author(s)
      Hiroshi Nakagawa, Yasumasa Joti, AkioKitao, Mikio Kataoka
    • Journal Title

      Biophysical Journal 95巻

      Pages: 2916-2923

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hydration effects onlow-frequency protein dynamics observed insimulated neutron scattering spectra2008

    • Author(s)
      asumasa Joti, Hiroshi Nakagawa, MikioKataoka, Akio Kitao
    • Journal Title

      BiophysicalJoumal 94巻

      Pages: 4435-4443

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Diverse Roles of Glycine Residues Conserved in Photoactive Yellow Proteins.2008

    • Author(s)
      Yasushi Imamoto
    • Journal Title

      Biophysical Journal 94

      Pages: 3620-3628

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of the N-terminal region in the function of the photosynthetic bacterium transcription regulator PpsR2008

    • Author(s)
      Yoichi Yamazaki
    • Journal Title

      Photochemistry and Photobiology 84

      Pages: 839-844

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mechanism of induced folding : Both folding before binding and binding before folding can be realized in staphylococcal nuclease mutants2008

    • Author(s)
      Masayoshi Onitsuka
    • Journal Title

      Proteins : Struetures, Functions and Bioinformatics 72

      Pages: 837-847

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hydration effects on low-frequency protein dynamics observed insimulated neutron scattering spectra2008

    • Author(s)
      Yasumasa Joti
    • Journal Title

      Biophysical Journal 94

      Pages: 4435-4443

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The photoreaction of the photoactive yellow protein domain in thelight sensor histidine kinase Ppr is influenced by the C-terminal domains2008

    • Author(s)
      Hironari Kamikubo
    • Journal Title

      Photochemistry and Photobiology 84

      Pages: 895-902

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Low-temperature spectroscopy of Metl00Ala mutant of photoactiveyellow protein2008

    • Author(s)
      Yasushi Imamoto
    • Journal Title

      Photochemistry and Photobiology 84

      Pages: 970-976

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Interaction between N-terminal loop and β-scaffold of photoactiveyellow protein2008

    • Author(s)
      Miki Harigai
    • Journal Title

      Photochemistry and Photobiology 84

      Pages: 1031-1037

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hydration affects both harmonic and anharmonic nature of proteindynamics2008

    • Author(s)
      Hiroshi Nakagawa
    • Journal Title

      Biophysical Journal 95

      Pages: 2916-2923

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nucleotide-dependent conformational changes and assembly of the AAA ATPase SKD1/VPS4B2008

    • Author(s)
      Michio Inoue
    • Journal Title

      Traffic 9

      Pages: 2180-2189

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] High resolution neutron crystallography of photoactive yellow protein-Discovery of low barrier hydrogen bond2011

    • Author(s)
      Mikio Kataoka
    • Organizer
      第3回韓日生体分子科学セミナー
    • Place of Presentation
      Cheju-do, Korea(招待)
    • Year and Date
      2011-02-27
    • Related Report
      2010 Annual Research Report
  • [Presentation] High resolution neutron crystal structure of photoactive yellow protein : Discovery of low barrier hydrogen bond2011

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 7th Asian Biophysics Association (ABA) Symposium
    • Place of Presentation
      New Delhi, India(招待)
    • Year and Date
      2011-02-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in ohotoreaction2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      International Chemical Congress of Pacific Basin Societies (PACIFICHEM 2010)
    • Place of Presentation
      Honolulu, U.S.A.(招待)
    • Year and Date
      2010-12-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Fluctuation controls enzymatic activity of Staphylococcal nuclease2010

    • Author(s)
      Hironari Kamikubo
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of the functional element of dihydrofolate reductase by the systematic alanine insertion2010

    • Author(s)
      Rumi Shiba
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] FRET analysis of structural changes in staphylococcal nuclease2010

    • Author(s)
      Yusuke Kishi
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      Zhonghua Wang
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-12-01
    • Related Report
      2010 Annual Research Report
  • [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in stanhvlococcal nuclease2010

    • Author(s)
      Hiroki Sawada
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-11-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] Measurements of loop formation in the denatured state of staphylococcal nuclease2010

    • Author(s)
      Mariko Yamaguchi
    • Organizer
      The 4th International Symposium "Molecular Science of Fluctuations toward Biological Functions"
    • Place of Presentation
      大津
    • Year and Date
      2010-11-30
    • Related Report
      2010 Annual Research Report
  • [Presentation] 中性子非弾性散乱と分子動力学によるタンパク質の揺らぎと水和水ダイナミクスの研究2010

    • Author(s)
      中川洋
    • Organizer
      日本物理学会 2010年秋季大会
    • Place of Presentation
      堺市
    • Year and Date
      2010-09-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛋白質機能の発現に構造は必須か?2010

    • Author(s)
      片岡幹雄
    • Organizer
      日本物理学会2010年秋季大会
    • Place of Presentation
      堺市
    • Year and Date
      2010-09-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Cytochrome c polymerization by successive domain swapping at the C-terminal helix2010

    • Author(s)
      Shun Hirota
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] A case of EspB from enterohaemorrhagic Escherichia coli2010

    • Author(s)
      Daizo Hamada
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] Property of a structural element of SNase-like domain inhuman p1002010

    • Author(s)
      Yoko Ogawa
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] The investigation of the relationship between non-local interaction and the effect of single alanine insertion in staphylococcal nuclease2010

    • Author(s)
      Hiroki Sawada
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] FRET analysis of structural changes in Staphylococcal nuclease2010

    • Author(s)
      Yusuke Kishi
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-22
    • Related Report
      2010 Annual Research Report
  • [Presentation] The mechanism of induced folding of Staphylococcal nuclease : Folding before binding or binding before folding?2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台(招待)
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effects of trehalose on the structures and dynamics of lipid membrane2010

    • Author(s)
      Tomomi Masui
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Solution structure of the light sensor histidine kinase of Ppr comprised of the PYP and Bph domains2010

    • Author(s)
      Junko Miura
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Solution structural analysis of Drosophila GGA2010

    • Author(s)
      Maiko Naruse
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Analysis of solution state of the interaction protein of Rc-PYP2010

    • Author(s)
      Miki Hayashi
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] The role of each residue in the flexible Ω loop of Staphylococcal nuclease on the catalytic activity2010

    • Author(s)
      Changjun Ahn
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Classification of the functional element of dihydrofolate reductase (DHFR) by the systemic alanine insertion2010

    • Author(s)
      Rumi Shiba
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Synthesis of an artificial enzyme by implanting the functional elements of SNase2010

    • Author(s)
      Hironari Kamikubo
    • Organizer
      第48回日本生物物群会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] Urea denaturation of staphylococcal nuclease monitored by tryptophan-cysteine distance2010

    • Author(s)
      Mariko Yamaguchi
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Substitution effects of basic residues in the photoactive yellow protein of Rhodobacter caplsulatus2010

    • Author(s)
      Yoichi Yamazaki
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      仙台
    • Year and Date
      2010-09-20
    • Related Report
      2010 Annual Research Report
  • [Presentation] Photoactive Yellow Proteinにおける発色団の機能変調2010

    • Author(s)
      山崎洋一
    • Organizer
      第16回日本光生物学協会年会
    • Place of Presentation
      吹田市
    • Year and Date
      2010-08-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of hydration water on protein dynamics2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 4th Shangai International Conference on Biophysics and Molecular Biology
    • Place of Presentation
      Shanghai-Jiashan, China
    • Year and Date
      2010-08-10
    • Related Report
      2010 Final Research Report
  • [Presentation] Effect of hydration water on protein dynamics2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 4th Shanghai International Conference on Biophysics and Molecular Biology
    • Place of Presentation
      Shanghai-Jiashan, China(招待)
    • Year and Date
      2010-08-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] The effect of alanine insertion mutation for folding process.2010

    • Author(s)
      Hiroki Sawada
    • Organizer
      The 4th Shanghai International Conference on Biophysics and Molecular Biology
    • Place of Presentation
      Shanghai-Jiashan, China
    • Year and Date
      2010-08-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] Extraction of the regions encoded foldability and/or functionability from dihvdrofolate reductase by the systematic alanine insertion2010

    • Author(s)
      Rumi Shiba
    • Organizer
      The 4th Shanghai International Conference on Biophysics and Molecular Biology
    • Place of Presentation
      Shanghai-Jiashan, China
    • Year and Date
      2010-08-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] 精子由来蛋白質IZUMO,その構造と受精膜融合での役割2010

    • Author(s)
      萩原義久
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析法を用いたジヒドロ葉酸還元酵素の機能発現及び構造形成領域の抽出2010

    • Author(s)
      芝るみ
    • Organizer
      第10回日本蛋白質科学会年会
    • Place of Presentation
      札幌
    • Year and Date
      2010-06-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] Effect of hydration on protein dynamics, Leopoldina-Symposium on the2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      Complexity Connecting Biomolecular Structure and Solvation Dynamics
    • Place of Presentation
      Bochum, Germany
    • Year and Date
      2010-05-26
    • Related Report
      2010 Final Research Report
  • [Presentation] Effect of hydration on protein dynamics2010

    • Author(s)
      Mikio Kataoka
    • Organizer
      Leopoldina-Symposium on the Complexity Connecting Biomolecular Structure and Solvation Dynamics
    • Place of Presentation
      Bochum, Germany(招待)
    • Year and Date
      2010-05-26
    • Related Report
      2010 Annual Research Report
  • [Presentation] structure and photoreaction of photoact ive yellow protein : Direct observation of low barrier hydrogen bond and its roles2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      ATI International Forum 2009, "Protein Structure Determination and Applications"
    • Place of Presentation
      茨城県東海村
    • Year and Date
      2009-03-09
    • Related Report
      2008 Annual Research Report
  • [Presentation] Mechanism of lnduced Folding of Staphylococcal Nuclease : Implication to Natively Unfolding Protein2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 6th Asian Biophysics Association (ABA) Symposium
    • Place of Presentation
      Hong Kong, China
    • Year and Date
      2009-01-12
    • Related Report
      2010 Final Research Report
  • [Presentation] Mechanism of Induced Folding of Staphylococcal Nuclease : Implication to Natively Unfolding Protein2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 6th Asian Biophysics Association (ABA)Symposium
    • Place of Presentation
      香港(中国)
    • Year and Date
      2009-01-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] タンパク質動力学に対する水和の効果2009

    • Author(s)
      片岡幹雄
    • Organizer
      第9回日本蛋白質科学会年会
    • Place of Presentation
      熊本
    • Related Report
      2009 Annual Research Report
  • [Presentation] イェロープロテインの低障壁水素結合の形成とその役割2009

    • Author(s)
      片岡幹雄
    • Organizer
      第36回生体分子化学討論会
    • Place of Presentation
      札幌
    • Related Report
      2009 Annual Research Report
  • [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      Telluride Science Research Center (TSRC) Work shop on Protein Dynamics 2009
    • Place of Presentation
      テルライド(アメリカ)
    • Related Report
      2009 Annual Research Report
  • [Presentation] Effect of Hydration Water on Protein Dynamics2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 3rd UT Horiba Interantional Symposium on Hydrogen and Water in Condensed Matter Physics
    • Place of Presentation
      千葉
    • Related Report
      2009 Annual Research Report
  • [Presentation] Photoactive Yellow Proteinの低障壁水素結合2009

    • Author(s)
      山口繁生
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 中性子非弾性散乱で蛋白質の熱揺らぎを測る2009

    • Author(s)
      片岡幹雄
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rc-PYPと相互作用タンパク質を用いた酵素活性の光制御系の作製2009

    • Author(s)
      久保晴政
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rhodobacter capsulatus由来PYPの相互作用様式の解析2009

    • Author(s)
      山崎洋一
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Rc-PYPの低温分光2009

    • Author(s)
      濱口祐也
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] キメラを用いたPhotoactive Yellow Proteinの研究2009

    • Author(s)
      松本啓佑
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Staphylococcal nucleaseアラニン挿入変異体の結晶学的研究2009

    • Author(s)
      吉岡紘志
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] エレメント置換による蛋白質の機能獲得の試み2009

    • Author(s)
      小賀坂彰浩
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] アゾベンゼンを用いた構造エレメントのモジュレーション2009

    • Author(s)
      齊藤謙介
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 誘導折り畳み反応のΦ値解析:スタフィロコッカルヌクレアーゼ変異体の誘導折り畳み反応におけるリガンド結合の役割2009

    • Author(s)
      鬼塚正義
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 電子常磁性共鳴分光法による天然変性Staphylococcal nuclease変異体の構造解析2009

    • Author(s)
      澤田宏起
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析法を用いたジヒドロ葉酸還元酵素の機能発現および構造形成領域の抽出2009

    • Author(s)
      芝るみ
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析によるHuman p100 SNase様ドメインの構造形成に関わる領域の抽出2009

    • Author(s)
      小川洋子
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] 蛋白質の調和運動と非調和運動に対する水和効果2009

    • Author(s)
      中川洋
    • Organizer
      第47回日本生物物理学会年会
    • Place of Presentation
      徳島
    • Related Report
      2009 Annual Research Report
  • [Presentation] Low barrier hydrogen bond in photoactive yellow protein and its role in photoreaction2009

    • Author(s)
      Mikio Kataoka
    • Organizer
      The 1st NCTU-NAIST workshop on "Molecular/Nano Science"
    • Place of Presentation
      新竹(台湾)
    • Related Report
      2009 Annual Research Report
  • [Presentation] 中性子結晶構造解析による蛋白質中の「低障壁」水素結合の発見2009

    • Author(s)
      上久保裕生
    • Organizer
      第9回日本中性子科学会年会
    • Place of Presentation
      茨城
    • Related Report
      2009 Annual Research Report
  • [Presentation] 蛋白質動力学転移における水和水の構造とダイナミクス2008

    • Author(s)
      中川洋
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] 光受容タンパク質AppAの分子内相互作用機構2008

    • Author(s)
      中西勇人
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] Human p100のSNase様ドメインの折れ畳み能2008

    • Author(s)
      米田知可子
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 網羅的アラニン挿入変異解析法によるジヒドロ葉酸還元酵素の機能発現及び構造形成領域の抽出2008

    • Author(s)
      芝るみ
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 拡散係数変化によるPYPの光反応における構造変化の起源の検討2008

    • Author(s)
      Javaid Shahbaz Khan
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] Photoactive yellow proteinの構造および機能エレメントの同定2008

    • Author(s)
      山田好輝
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-04
    • Related Report
      2008 Annual Research Report
  • [Presentation] 核酸分解酵素におけるループの揺らぎと機能の関係2008

    • Author(s)
      田所成文
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] L108が担うStaphylococcal Nucleaseの折り畳みにおける役割の解明2008

    • Author(s)
      中垣礼寧
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] アラニン挿入変異がキネティクスに与える影響2008

    • Author(s)
      渾田宏起
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Rhodobacter capsulatus由来PYPの複合体状態における分光学的特長2008

    • Author(s)
      山崎洋一
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] 光センサー型ヒスチジンキナーゼPYPドメインの光反応に対するC末端ドメインの影響2008

    • Author(s)
      上久保裕生
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Rc-PYPにおけるN末端部位の役割2008

    • Author(s)
      太田成人
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Photoactive Yellow Protein中の2種のshort hydrogen bondの直接観察2008

    • Author(s)
      山口繁生
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Year and Date
      2008-12-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of hydration water on protein dynamics2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      150th Anniversary of Japan-France Relation-ship Workshop on Water & Cell Physiology
    • Place of Presentation
      京都
    • Year and Date
      2008-11-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of hydration on the glass-liketransition of protein2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      JSPS Japan-France Bilateral Joint Seminar 2008"Frontiers of Glassy Physics"
    • Place of Presentation
      京都
    • Year and Date
      2008-11-19
    • Related Report
      2010 Final Research Report
  • [Presentation] Effect of hydration on the glass-1ike transition of protein2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      Japan-France Bilateral Joint Seminar 2008“Frontiers of Glassy Physics"
    • Place of Presentation
      京都
    • Year and Date
      2008-11-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] Protein Dynamics and Structure Studied by Neutron Scattering2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      Asia Science Seminar on"Frontier Science at High-lntensity Proton Accelerators"
    • Place of Presentation
      Beijing, China
    • Year and Date
      2008-10-21
    • Related Report
      2010 Final Research Report
  • [Presentation] Protein Dynamics and structure studied by Neutron Scattering2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      Asia Science Seminar on “Frontier Scienceat High-Intensity Proton Accelerators"
    • Place of Presentation
      北京(中国)
    • Year and Date
      2008-10-21
    • Related Report
      2008 Annual Research Report
  • [Presentation] Effect of hydration and conformational state on protein dynamics2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      Workshop on Biomolecular Dynamics and Protein-Water Interactions
    • Place of Presentation
      Munich, German
    • Year and Date
      2008-09-25
    • Related Report
      2010 Final Research Report
  • [Presentation] Effect of hydration and conformational state on proteindynamics2008

    • Author(s)
      Mikio Kataoka
    • Organizer
      Workshop Biomolecular Dynamics and Protein-Water Interactions
    • Place of Presentation
      ミュンヘン(ドイツ)
    • Year and Date
      2008-09-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] Staphylococcal nucleaseの誘導折り畳み機構2008

    • Author(s)
      片岡幹雄
    • Organizer
      第8回日本蛋白質科学会年会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-10
    • Related Report
      2008 Annual Research Report
  • [Book] in"Neutrons in Soft Matter"(eds.by T.Imae, T.Kanaya, M.Furusaka, N.Torikai)John Wiley2011

    • Author(s)
      Mikio Kataoka, Hiroshi Nakagawa
    • Publisher
      Protein dynamics studied by neutron incoherent scattering
    • Related Report
      2010 Final Research Report
  • [Book] Water, The Forgotten Biological Molecule(eds.by Denis Le Bihan and Hidenao Fukuyama), Pan Stanfbrd Publishing(Singapore)2011

    • Author(s)
      Mikio Kataoka, H.iroshi Nakagawa
    • Publisher
      Effect of hydration on protein dynamics in
    • Related Report
      2010 Final Research Report
  • [Book] Water, The Forgotten Biological Molecule2011

    • Author(s)
      Mikio Kataoka
    • Publisher
      Pan Stanford Publishing
    • Related Report
      2010 Annual Research Report
  • [Book] Neutrons in Soft Matter2011

    • Author(s)
      Mikio Kataoka
    • Publisher
      John Wiley(in press)
    • Related Report
      2010 Annual Research Report
  • [Book] 揺らぎと生体機能(MedicalBio 10月別冊)2011

    • Author(s)
      片岡幹雄
    • Publisher
      オーム社
    • Related Report
      2010 Annual Research Report
  • [Book] 光ナノ科学への招待2011

    • Author(s)
      片岡幹雄
    • Publisher
      化学同人
    • Related Report
      2010 Annual Research Report
  • [Book] 鍵と鍵穴か、誘導適合か-天然変性蛋白質における認識・結合分子機構の検討,in揺らぎと生体機能(MedicalBio 10月別冊,寺嶋正秀監修)2010

    • Author(s)
      片岡幹雄
    • Publisher
      オーム社
    • Related Report
      2010 Final Research Report
  • [Book] Protein dynamics studied by neutron incoherent scattering2010

    • Author(s)
      Mikio Kataoka
    • Publisher
      John Wiley(印刷中)
    • Related Report
      2009 Annual Research Report
  • [Book] Structure of the photointermediate of photoactive yellow protein and the propagataion mechanism of structural change, in"Water and Biomolecules (eds.by K.Kuwaj ima, Y.Goto, F.Hirata, M.Kataoka, M.Terazima)2009

    • Author(s)
      M.Kataoka, H.Kamikubo
    • Publisher
      Springer-Verleg (Berlin)
    • Related Report
      2010 Final Research Report
  • [Book] イェロープロテインと関連蛋白質,in光科学研究の最前線2(編集委員会編),光科学研究の最前線22009

    • Author(s)
      片岡幹雄
    • Total Pages
      208
    • Publisher
      強光子場科学研究懇談会
    • Related Report
      2010 Final Research Report

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Published: 2008-04-01   Modified: 2016-04-21  

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