• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The second ATP-binding site of the chaperonin GroEL and its functional role

Research Project

Project/Area Number 20370066
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biophysics
Research InstitutionNational Institutes of Natural Sciences Okazaki Research Facilities

Principal Investigator

KUWAJIMA Kunihiro  National Institutes of Natural Sciences Okazaki Research Facilities, 岡崎統合バイオサイエンスセンター, 教授 (70091444)

Project Period (FY) 2008 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥20,670,000 (Direct Cost: ¥15,900,000、Indirect Cost: ¥4,770,000)
Fiscal Year 2010: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2009: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2008: ¥10,010,000 (Direct Cost: ¥7,700,000、Indirect Cost: ¥2,310,000)
Keywords分子シャペロン / シャペロニン / ATP結合 / アロステリック転移 / 生物物理 / 分子機械 / 分子認識 / 生体分子 / 蛋白質
Research Abstract

The Escherichia coli chaperonin GroEL, a molecular chaperone that mediates protein folding in the biological cell, expresses its chaperone function through ATP binding. In the present study, we investigated the ATP binding to GroEL by photo-affinity labeling, amino acid sequence analysis, stopped-flow fluorescence spectroscopy, and isothermal titration calorimetry. We found (1) that the second ATP-binding site is present and located near Tyr360, and (2) that in the absence of potassium ion, only the ATP binding to the primary site was observed, and its binding constant is an order of 10^4M^<-1>.

Report

(4 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • 2008 Annual Research Report
  • Research Products

    (69 results)

All 2011 2010 2009 2008 Other

All Journal Article (19 results) (of which Peer Reviewed: 16 results) Presentation (44 results) Book (2 results) Remarks (4 results)

  • [Journal Article] Dissecting a bimolecular process of MgATP2. binding to the chaperonin GroEL.2011

    • Author(s)
      Chen, J., Makabe K., Nakamura T., Inobe, T. Kuwajima K.
    • Journal Title

      J.Mol.Biol., in the press.

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Dissecting a bimolecular process of MgATP^<2-> binding to the chaperonin GroEL2011

    • Author(s)
      Jin Chen
    • Journal Title

      J.Mol.Biol.

      Volume: 印刷中

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 何が蛋白質のフォールディング経路を決めるのか?2010

    • Author(s)
      中村敬, 真壁幸樹, 桑島邦博
    • Journal Title

      Medical Bio 9月号別冊「揺らぎと生体機能」オーム社東京

      Pages: 52-57

    • Related Report
      2010 Final Research Report
  • [Journal Article] Adaptation of a hyperthermophilic group II chaperonin to relatively moderate temperatures.2010

    • Author(s)
      Kanzaki, T., Ushioku, S., Nakagawa, A., Oka, T., Takahashi, K., Nakamura T., Kuwajima K. Yamagishi, A. Yohda, M.
    • Journal Title

      Protein Eng.Des.Sel. 23

      Pages: 393-402

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Different folding pathways taken by highly homologous proteins, goat α-lactalbumin and canine milk lysozyme.2010

    • Author(s)
      Nakamura T., Makabe K., Tomoyori, K., Maki, K., Mukaiyama, A. Kuwajima, K.
    • Journal Title

      J.Mol.Biol. 396

      Pages: 1361-1378

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Flexible recognition of the tRNA G18 methylation target site by TrmH methyltransferase through first binding and induced fit processes.2010

    • Author(s)
      Ochi, A., Makabe K., Kuwajima K., Hori, H.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 9018-9029

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 何がタンパク質のフォールディング経路を決めるのか?2010

    • Author(s)
      中村敬
    • Journal Title

      MedicalBio(オーム社)

      Volume: 10月号別冊 Pages: 49-54

    • Related Report
      2010 Annual Research Report
  • [Journal Article] Flexible recognition of the tRNA G18 methylation target site by Trm Hmethyltransferase through first binding and induced fit processes2010

    • Author(s)
      A.Ochi
    • Journal Title

      J.Biol.Chem. 285

      Pages: 9018-9029

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Adaptation of a hyperthermophilic group II chaperonin to relatively moderate temperatures2010

    • Author(s)
      T.Kanzaki
    • Journal Title

      Protein.Eng.Des.Sel. 23

      Pages: 393-402

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Different folding pathways taken by highly homologous proteins, goat α-lactalbumin and canine milk lysozyme2010

    • Author(s)
      T.Nakamura
    • Journal Title

      J.Mol.Biol. 396

      Pages: 1361-1378

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-native-helix formation is not necessary for folding of lipocalin : Comparison of burst-phase folding between tear lipocalin and β-lactoglobulin.2009

    • Author(s)
      Tsukamoto, S., Yamashita, T., Yamada, Y., Fujiwara, K., Maki, K., Kuwajima K., Matsumura, Y., Kihara, H., Tsuge, H. Ikeguchi, M.
    • Journal Title

      Proteins 76

      Pages: 226-236

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Non-native α-helix formation is not necessary for folding of lipocalin : comparison of burst-phase folding between tear lipocalin and B-lactoglobulin2009

    • Author(s)
      S.Tsukamoto
    • Journal Title

      Proteins 76

      Pages: 226-236

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Non-native α-helix formation is not necessary for folding of lipocalin : Comparison of burst-phase folding between tear lipocalin and β-lactoglobulin2009

    • Author(s)
      S. TSUKAMOTO
    • Journal Title

      Proteins (掲載確定印刷中)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Asymmetry of the GroEL-GroES complex under physiological conditions as revealed by small-angle X-ray scattering.2008

    • Author(s)
      Inobe, T., Takahashi, K., Maki, K., Enoki, S., Kamagata, K., Kadooka, A., Arai, M. Kuwajima K.
    • Journal Title

      Biophys.J. 94

      Pages: 1392-1402

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Probing force- induced unfolding intermediates of a single staphylococcal nuclease molecule and the effect of ligand binding.2008

    • Author(s)
      Ishii, T., Murayama, Y., Katano, A., Maki, K., Kuwajima K. Sano, M.
    • Journal Title

      Biochem. Biophys. Res.Commun. 375

      Pages: 586-591

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sequential action of ATP-dependent subunit conformational change and interaction between helical protrusions in the closure of the built-in lid of group II chaperonins.2008

    • Author(s)
      Kanzaki, T., Iizuka, R., Takahashi, K., Maki, K., Masuda, R., Sahlan, M., Yebenes, H., Valpuesta, J.M., Oka, T., Furutani, M., Ishii, N., Kuwajima K., Yohda, M.
    • Journal Title

      J.Biol.Chem. 283

      Pages: 34773-34784

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 真性体および組換え体αラクトアルブミンの構造の安定性とダイナミクス2008

    • Author(s)
      桑島邦博
    • Journal Title

      Milk Science 56

      Pages: 119-122

    • Related Report
      2010 Final Research Report
  • [Journal Article] Sequential Action of ATP-dependent Subunit Conformational Change and Interaction between Helical Protrusions in the Closure of the Built-in Lid of Group II Chaperonins2008

    • Author(s)
      T. KANZAKI
    • Journal Title

      J. Biol. Chem. 283

      Pages: 34773-34784

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Probing force-induced unfolding intermediates of a single staphylococcal nuclease molecule and the effect of ligand binding2008

    • Author(s)
      T. ISHII
    • Journal Title

      Biochem. Biophys. Res. Commun. 375

      Pages: 586-591

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Presentation] Molecular mechanisms of the Escherichia coli chanperonin function2011

    • Author(s)
      邦博桑島
    • Organizer
      3rd APPA Conference
    • Place of Presentation
      Shanghai University, Shanghai, China
    • Year and Date
      2011-05-07
    • Related Report
      2010 Final Research Report
  • [Presentation] Solution-phase H/D exchange coupled with FT-ICR MS to probe conformational dynamics of the ATP-dependent chaperone, GroEL2011

    • Author(s)
      Q.Zhang, H.-M.Zhang, J.Chen, M.R.Emmett, C.L.Hendricksonl, K.Kuwajima A.G.Marshall
    • Organizer
      8th North America FT MS Conference
    • Place of Presentation
      Key West, Florida, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Folding mechanism of β_2-microglobulin and its relationship to dialysis-related amyloidosis2011

    • Author(s)
      A.Mukaiyama, T.Nakamura, K.Makabe, K.Maki, Y.Goto, K.Kuwajima
    • Organizer
      3rd Japan-Korea Seminar on Biomolecular Sciences-Experiments and simulations
    • Place of Presentation
      Lotte Hotel, Jeju, Korea
    • Related Report
      2010 Final Research Report
  • [Presentation] "Identification of fatty-acid binding site in the anti-tumor complex of of-lactalbuin by 920-MHz NMR spectroscopy," IPR Seminar "Cooperation in Protein Science between Asian and Pacific Countries"2010

    • Author(s)
      邦博桑島
    • Organizer
      the Institute for Protein Research
    • Place of Presentation
      Osaka University
    • Year and Date
      2010-06-14
    • Related Report
      2010 Final Research Report
  • [Presentation] Identification of fatty-acid binding site in the anti-tumor complex of of α-lactalbuin by 920-MHz NMR spectroscopy2010

    • Author(s)
      K.Kuwajima
    • Organizer
      IPR Seminar"Cooperation in Protein Science between Asian and Pacific Countries, "
    • Place of Presentation
      the Institute for Protein Research, Osaka University(大阪)
    • Year and Date
      2010-06-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 蛋白質フォールディング問題とバイオサイエンス2010

    • Author(s)
      桑島邦博
    • Organizer
      蛋白研-統合バイオ共同セミナー
    • Place of Presentation
      大阪大学蛋白質研究所
    • Year and Date
      2010-04-22
    • Related Report
      2010 Final Research Report
  • [Presentation] Molecular Mechanisms of Protein Folding2010

    • Author(s)
      邦博桑島
    • Organizer
      The Overseas Sokendai Lecture in Bangkok FY2010&The Inaugural CU-IMS Joint Symposium
    • Place of Presentation
      Chulalongkorn University, Bangkok, Thailand
    • Related Report
      2010 Final Research Report
  • [Presentation] Identification of fatty-acid binding site in the anti-tumor complex of of α-lactalbuin by 920-MHz NMR spectroscopy2010

    • Author(s)
      邦博桑島
    • Organizer
      The 10th KIAS Conference on Protein Structure and Function, Korea Institute for Advanced Study (KIAS), Seoul, Korea
    • Place of Presentation
      Seoul, Korea
    • Related Report
      2010 Final Research Report
  • [Presentation] 蛋白質フォールディング経路の速度論的理解2010

    • Author(s)
      桑島邦博
    • Organizer
      2010年日本物理学会秋季大会シンポジウム「揺らぎが決める生体分子の構造形成と機能発現」
    • Place of Presentation
      大阪府立大学・中百舌鳥キャンパス
    • Related Report
      2010 Final Research Report
  • [Presentation] "Is the Folding Pathway Conserved in Homologous Proteins?," Bit Life Science's 3rd Annual Protein and Peptide Conference "After a Solution of the Machines of Life,"2010

    • Author(s)
      邦博桑島
    • Organizer
      Beijing International Convention Center
    • Place of Presentation
      Beijing, China
    • Related Report
      2010 Final Research Report
  • [Presentation] Molecular mechanisms of protein folding," 2010 Annual Meeting of Asian CORE Program "Frontiers of Materials, Photo-, and Theoretical Molecular Sciences2010

    • Author(s)
      邦博桑島
    • Organizer
      Insitute of Atomic and Molecular Sciences, Academia Sinica
    • Place of Presentation
      Taipei, Taiwan
    • Related Report
      2010 Final Research Report
  • [Presentation] Dissecting a bimolecular mechanism of ATP binding to the chaperonin GroEL," 4^th International Symposium of "Molecular Science of Fluctuations toward Biological Functions2010

    • Author(s)
      J.Chen, K.Makabe, K.Kuwajima
    • Organizer
      Piaza Omi, Ohtsu
    • Place of Presentation
      Piaza Omi, Ohtsu
    • Related Report
      2010 Final Research Report
  • [Presentation] The molten globule state and its biological function in α-lactalbumin", 4^th International Symposium of "Molecular Science of Fluctuations toward Biological Functions"2010

    • Author(s)
      T.Nakamura, K.Makabe, T.Aizawa, K.Kawano, M.Demura K.Kuwajima
    • Organizer
      Piaza Omi, Ohtsu
    • Related Report
      2010 Final Research Report
  • [Presentation] Folding study of outer surface protein A The 4^th International Symposium of Molecular science of fluctuations toward biological functions2010

    • Author(s)
      K.Makabe, T.Nakamura, K.Kuwajima
    • Organizer
      Piaza Omi, Ohtsu
    • Related Report
      2010 Final Research Report
  • [Presentation] Dissect a bimolecular mechanism of ATP binding to the chaperonin GroEL2010

    • Author(s)
      J.Chen, K.Makabe, K.Kuwajima
    • Organizer
      YSF forum, OzBio2010 conference, 12^th IUBMB conference, 21^st FAOBMB conference
    • Place of Presentation
      Melbourne, Australia
    • Related Report
      2010 Final Research Report
  • [Presentation] Folding study of outer surface protein A2010

    • Author(s)
      K.Makabe, T.Nakamura, K.Kuwajima
    • Organizer
      24^th annual symposium of the protein society
    • Place of Presentation
      San Diego, USA
    • Related Report
      2010 Final Research Report
  • [Presentation] Dissect a bimolecular mechanism of ATP binding to the chaperonin GroEL2010

    • Author(s)
      J.Chen, K.Makabe, K.Kuwajima
    • Organizer
      35^th FEBS Congress
    • Place of Presentation
      Gothenburg, Sweden
    • Related Report
      2010 Final Research Report
  • [Presentation] Identification of fatty-acid binding site in the anti-tumor complex of of α-lactalbuin by 920-MHz NMR spectroscopy2010

    • Author(s)
      K.Kuwajima
    • Organizer
      The 10th KIAS Conference on Protein Structure and Function
    • Place of Presentation
      Korea Institute for Advanced Study, Seoul(Korea)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular Mechanisms of Protein Folding2010

    • Author(s)
      K.Kuwajima
    • Organizer
      The Overseas Sokendai Lecture in Bangkok FY2010 & The Inaugural CU-IMS Joint Symposium
    • Place of Presentation
      Chulalongkorn University, Bangkok(Thailand)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular Mechanisms of Protein Folding2010

    • Author(s)
      K.Kuwajima
    • Organizer
      2010 Annual Meeting of Asian CORE Program "Frontiers of Materials, Photo-, and Theoretical Molecular Sciences"
    • Place of Presentation
      Institute of Atomic and Molecular Sciences, Academia Sinica, Taiwan
    • Related Report
      2009 Annual Research Report
  • [Presentation] Is the folding pathway conserved in homologous proteins?2010

    • Author(s)
      K.Kuwajima
    • Organizer
      PepCon-2010
    • Place of Presentation
      Beijing International Convention Center, China
    • Related Report
      2009 Annual Research Report
  • [Presentation] A Potassium Switch of ATP-Induced GroEL Conformational Changes2009

    • Author(s)
      J.Chen, K.Makabe, K.Kuwajima
    • Organizer
      2nd Japan-Korea Seminar on Biomolecular Sciences .Experiments and Simulations (Asian Core Program by JSPS), Symposion Hall
    • Place of Presentation
      Nagoya University
    • Related Report
      2010 Final Research Report
  • [Presentation] The molten globule state and its biological function in-lactalbumin2009

    • Author(s)
      T.Nakamura, K.Makabe, T.Aizawa, K.Kawano, M.Demura, K.Kuwajima
    • Organizer
      2nd Japan-Korea Seminar on Biomolecular Sciences-Experiments and Simulations (Asian Core Program by JSPS), Symposion Hall
    • Place of Presentation
      Nagoya University
    • Related Report
      2010 Final Research Report
  • [Presentation] Role of the Main-Chain Hydrogen Bonding in-Sheet Register2009

    • Author(s)
      K.Makabe, S.Koide, K.Kuwajima
    • Organizer
      2nd Japan-Korea Seminar on Biomolecular Sciences.Experiments and Simulations (Asian Core Program by JSPS)
    • Place of Presentation
      Symposion Hall Nagoya University
    • Related Report
      2010 Final Research Report
  • [Presentation] Hydrogen-exchange kinetics of the Escherichia coli chaperonin complex2009

    • Author(s)
      A.Mukaiyama, T.Takahashi, K.Makabe, K.Kuwajima
    • Organizer
      2nd Japan-Korea Seminar on Biomolecular Science-Experiments and Simulations (Asian Core Program by JSPS)
    • Place of Presentation
      Symposion Hall, Nagoya University
    • Related Report
      2010 Final Research Report
  • [Presentation] A minor component of native β2-microglobulin and its relationship to dialysis-related amyloidosis2009

    • Author(s)
      邦博桑島
    • Organizer
      The 9th KIAS.SNU Conference on Protein Structure and Function
    • Place of Presentation
      Seoul National University, Seoul, Korea
    • Related Report
      2010 Final Research Report
  • [Presentation] 大腸菌シャペロニンの構造ダイナミクスと機能発現2009

    • Author(s)
      桑島邦博
    • Organizer
      第58高分子討論会シンポジウム「生体に学ぶセンシング,物質輸送,分離」
    • Place of Presentation
      熊本大学工学部
    • Related Report
      2010 Final Research Report
  • [Presentation] Hydrogen-exchange kinetics of the Escherichia coli chaperonin complex," Japan-Korea Symposium on Molecular Science 2009 "Chemical Dynamics in Materials and Biological Molecular Sciences2009

    • Author(s)
      邦博桑島
    • Organizer
      Asian Core Program by JSPS
    • Place of Presentation
      Awaji Yumebutai International Conference Center
    • Related Report
      2010 Final Research Report
  • [Presentation] 大腸菌シャペロニンの構造ダイナミクスと機能発現2009

    • Author(s)
      桑島邦博
    • Organizer
      第9回日本蛋白質科学会年会ワークショップ「生体分子の揺らぎと機能
    • Place of Presentation
      熊本全日空ホテル
    • Related Report
      2010 Final Research Report
  • [Presentation] 相同蛋白質のフォールディング機構:αラクトアルブミンとリゾチームの比較研究2009

    • Author(s)
      桑島邦博
    • Organizer
      次世代スパコンプロジェクト・ナノ分野グランドチャレンジ研究開発・ナノ統合拠点分子科学WG連続研究会「タンパク質制御(フォールディング)
    • Place of Presentation
      東京医科歯科大学
    • Related Report
      2010 Final Research Report
  • [Presentation] Folding mechanism of homologous proteins : A comparative study betweenα-lactalbumin and lysozyme2009

    • Author(s)
      邦博桑島
    • Organizer
      科研費特定領域研究「水と生体分子」成果取りまとめ公開シンポジウム
    • Place of Presentation
      岡崎コンファレンスセンター
    • Related Report
      2010 Final Research Report
  • [Presentation] Pathway vs.funnel perspectives of protein folding2009

    • Author(s)
      邦博桑島
    • Organizer
      Korea-Japan Seminars on Biomolecular Sciences.Experiments and Simulations (Asian Core Program by JSPS)Korea Institute for Advanced Study (KIAS)
    • Place of Presentation
      Korea
    • Related Report
      2010 Final Research Report
  • [Presentation] シャペロニンの構造揺らぎとフォールディング介助機能2009

    • Author(s)
      桑島邦博
    • Organizer
      科研費新学術領域研究「揺らぎと生体機能」第1回公開シンポジウム
    • Place of Presentation
      京都テレサ
    • Related Report
      2010 Final Research Report
  • [Presentation] Hydrogen-exchange kinetics of the Escherichia coli chaperonin complex2009

    • Author(s)
      K.Kuwajima
    • Organizer
      Japan-Korea Symposium on Molecular Science 2009 "Chemical Dynamics in Materials and Biological Molecular Sciences"
    • Place of Presentation
      Awaji Yumebutai International Conference Center, Awajishima, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] A minor component of native β2-microglobulin and its relationship to dialysis-related amyloidosis2009

    • Author(s)
      K.Kuwajima
    • Organizer
      The 9th KIAS-SNU Conference on Protein Structure and Function, Seoul National University
    • Place of Presentation
      Seoul National University, Seoul, Korea
    • Related Report
      2009 Annual Research Report
  • [Presentation] Hydrogen-exchange kinetics of the Escherichia coli chaperonin complex2009

    • Author(s)
      K.Kuwajima
    • Organizer
      2nd Japan-Korea Seminar on Biomolecular Sciences -Experiments and Simulations
    • Place of Presentation
      Nagoya University, Nagoya, Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] Molecular Mechanisms of the Chaperone Function of GroEL2008

    • Author(s)
      桑島邦博
    • Organizer
      8th KIAS-Yonsei Conference on Protein Structure and Function
    • Place of Presentation
      Seoul, Korea.
    • Year and Date
      2008-10-11
    • Related Report
      2008 Annual Research Report
  • [Presentation] Folding Mechanisms of Homologous Proteins : A Comparative Study between Lysozyme and α-Lactalbumin2008

    • Author(s)
      桑島邦博
    • Organizer
      ACS 236^<th> National Meeting Symposium
    • Place of Presentation
      Philadelphia, U. S. A.
    • Year and Date
      2008-08-21
    • Related Report
      2008 Annual Research Report
  • [Presentation] αラクトアルブミンとリゾチームのフォールディング経路はなぜ違うのか?2008

    • Author(s)
      桑島邦博
    • Organizer
      札幌生体高分子シンポジウム
    • Place of Presentation
      北海道大学・学術交流会館
    • Related Report
      2010 Final Research Report
  • [Presentation] Molecular Mechanisms of the Chaperone Function of GroEL2008

    • Author(s)
      邦博桑島
    • Organizer
      the 8th KIAS-Yonsei Conference on Protein Structure and Function
    • Place of Presentation
      Seoul (Korea)
    • Related Report
      2010 Final Research Report
  • [Presentation] Folding Mechanisms of Homologous Proteins : A Comparative Study between Lysozyme and alph-Lactalbumin2008

    • Author(s)
      邦博桑島
    • Organizer
      ACS 236^th National Meeting Symposium Protein Folding Dynamics: Experiment and Theory
    • Place of Presentation
      Philadelphia (U.S.A.)
    • Related Report
      2010 Final Research Report
  • [Presentation] Folding Mechanism of Homologous Proteins : A Comparative Study ofα-Lactalbumin and Lysozyme2008

    • Author(s)
      邦博桑島
    • Organizer
      膜蛋白質研究国際フロンティア国際シンポジウム
    • Place of Presentation
      千里ライフサイエンスセンター(吹田市)
    • Related Report
      2010 Final Research Report
  • [Presentation] 相同蛋白質のフォールディング機構イヌ乳リゾチームとヤギαラクトアルブミンの比較研究2008

    • Author(s)
      桑島邦博
    • Organizer
      次世代スーパーコンピュータプロジェクト「ナノ分野グランドチャレンジ研究開発」第2回公開シンポジウム
    • Place of Presentation
      岡崎コンファレンスセンター
    • Related Report
      2010 Final Research Report
  • [Presentation] Folding Mechanisms of Homologous Proteins : A Comparative Study between Lysozyme and α-Lactalbumin2008

    • Author(s)
      邦博桑島
    • Organizer
      2nd Pacific Rim International Conference of Protein Science
    • Place of Presentation
      Cairns (Australia)
    • Related Report
      2010 Final Research Report
  • [Book] A.Experimental and Simulation Studies of the Folding/Unfolding of Goat α-Lactalbumin In : Water and Biomolecules-Physical Chemistry of Life Phenomena. (Kuwajima.K, Goto.Y, Hirata.F, Kataoka.M.& Terazima. M, Eds.)2009

    • Author(s)
      Kuwajima, K., Oroguchi, T., Nakamura, T., Ikeguchi, M. Kidera
    • Publisher
      Springer-Verlag.
    • Related Report
      2010 Final Research Report
  • [Book] Water and Biomolecules-Physical Chemistry of Life Phenomena2009

    • Author(s)
      K. Kuwajima
    • Total Pages
      307
    • Publisher
      Springer-Verlag, Berlin & Heidelberg
    • Related Report
      2008 Annual Research Report
  • [Remarks] ホームページ

    • URL

      http://gagliano.ims.ac.jp/

    • Related Report
      2010 Final Research Report
  • [Remarks]

    • URL

      http://gagliano.ims.ac.jp/Welcome.html

    • Related Report
      2010 Annual Research Report
  • [Remarks]

    • URL

      http://gagliano.ims.ac.jp/Welcome.html

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://gagliano.ims.ac.jp/Welcome.html

    • Related Report
      2008 Annual Research Report

URL: 

Published: 2008-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi