| Budget Amount *help |
¥20,280,000 (Direct Cost: ¥15,600,000、Indirect Cost: ¥4,680,000)
Fiscal Year 2010: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2009: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2008: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
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| Research Abstract |
Recent emerging evidence suggested that a functional linkage among transcription, pre-mRNA splicing and nuclear mRNA export, which had been analyzed independently, exists in a living cell. However, the molecular mechanism of the linkage still remains unclear. In this study, we analyzed the genes responsible for the fission yeast mutations that cause defective pre-mRNA splicing and nuclear mRNA export, and elucidated a part of the molecular mechanism of coordinated regulation of gene expression in eukaryotic cells.
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